Oxolin

2024 Author: Rachel Wainwright | [email protected]. Last modified: 2023-12-15 07:39

Oxolin: instructions for use and reviews

1. Release form and composition
2. Pharmacological properties
3. Indications for use
4. Contraindications
5. Method of application and dosage
6. Side effects
7. Overdose
8. Special instructions
9. Application during pregnancy and lactation
10. Drug interactions
11. Analogs
12. Terms and conditions of storage
13. Terms of dispensing from pharmacies
14. Reviews
15. Price in pharmacies

Latin name: Oxolinum

ATX code: S01AD

Active ingredient: dioxotetrahydroxytetrahydronaphthalene (dioxotetrahydrooxytetrahydronaphthaline)

Producer: Sintez OJSC, Tula Pharmaceutical Factory LLC, Promomed Rus LLC, Altayvitamins CJSC, Nizhpharm JSC, Murom Instrument-Making Plant OJSC, Zelenaya Dubrava CJSC, Biosintez OJSC, Ozone (Russia)

Description and photo update: 2019-16-08

Prices in pharmacies: from 30 rubles.

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Oxolin is a local antiviral drug.

Release form and composition

Dosage forms of Oxolinum release:

Ointment for topical application 0.25%: from light yellow to white, during storage, the appearance of a pink tint is permissible (in aluminum or laminate tubes of 5, 10 or 30 g, 1 tube in a cardboard box);
Nasal ointment 0.25%: from light yellow to white, during storage, the appearance of a pink tint is permissible (in aluminum or laminate tubes of 10, 15, 25, 30 g, 1 tube each in a cardboard box; 5, 10, 15, 20, 25, 30 g in glass cans, 20, 30, 40 cans in a cardboard box);
Ointment for external use 3%: from light yellow to white, during storage, the appearance of a pink tint is permissible (in aluminum or plastic tubes or in cans of 10, 15, 20, 25, 30, 40 or 50 g, 1 tube each or a jar in a cardboard box).

The composition of 100 mg of Oksolin ointment for topical use includes:

Active substance: dioxotetrahydroxytetrahydronaphthalene (oxoline) - 0.25 mg;
Auxiliary components: liquid paraffin (liquid paraffin), citric acid, vaseline - up to 100 mg.

The composition of 100 mg of Oksolin nasal ointment includes:

Active substance: dioxotetrahydroxytetrahydronaphthalene (oxoline) - 0.25 mg;
Auxiliary components: liquid paraffin (liquid paraffin) - 0.5 mg, petroleum jelly - up to 100 mg.

The composition of 100 mg of Oksolin external ointment includes:

Active ingredient: dioxotetrahydroxytetrahydronaphthalene (oxoline) - 3 mg;
Auxiliary component: petroleum jelly - up to 100 mg.

Pharmacological properties

Pharmacodynamics

The drug is characterized by a virucidal effect on the influenza virus, which manifests itself in direct contact with the virus-containing material. Dioxotetrahydroxytetrahydronaphthalene prevents the reproduction of the virus after it enters cells and blocks the binding sites of the influenza virus (mainly type A2) with the surface of cell membranes.

Pharmacokinetics

When applied to the nasal mucosa, up to 20% of dioxotetrahydroxytetrahydronaphthalene is absorbed. In the body, the substance does not accumulate and is excreted in the urine for 24 hours.

Indications for use

Topical ointment, nasal ointment

Eye diseases, rhinitis with viral etiology (treatment);
Influenza (prevention).

Ointment for external use

Oxolinum is used to treat warts, flat and common, and genital warts.

Contraindications

An absolute contraindication is hypersensitivity to the components of the ointment.

With caution, Oxolin should be prescribed during pregnancy, during breastfeeding, as well as for the treatment of children under 2 years of age.

Instructions for the use of Oxolin: method and dosage

Nasal ointment, topical ointment

Topical ointment and nasal ointment Oxolin are applied topically.

The dosage regimen is determined by the indications (for children and adults):

Viral rhinitis (treatment): application area - nasal mucosa, strip length - 3-5 mm, frequency of application - 2-3 times a day, course duration - 3-4 days;
Viral diseases of the eyes: method of application - lay behind the lower eyelid, strip length - 2-3 mm, frequency of application - 3-4 times a day; as part of combined treatment with other antiviral drugs - frequency of use - 1 time per day at night;
Influenza (prevention): area of application - nasal mucosa, strip length - 3-5 mm, frequency of application - 2-3 times a day. The drug is recommended for use in contact with patients with influenza and / or during the rise and maximum development of an epidemic outbreak of influenza (course duration - 25 days).

Ointment for external use

Oxolin is used externally, lubricating the surface of warts (including genital warts).

The frequency of application is 2-3 times a day, the duration of the treatment course is from 14 days to 2 months.

After applying the ointment, occlusive dressings with wax paper can be applied to enhance the effect.

Side effects

Possible side effects:

Nasal ointment, topical ointment: burning sensation of the eyes or nasal mucosa, rhinorrhea;
Ointment for external use: dermatitis, burning sensation, skin staining blue (easy to wash off).

Overdose

Overdose cases of Oxolinum have not been registered at the moment.

special instructions

Do not exceed the dosage regimen recommended in the instructions.

Influence on the ability to drive vehicles and complex mechanisms

According to the instructions, Oxolin does not affect the performance of potentially hazardous work requiring increased concentration and immediate psychomotor reactions (driving vehicles, activities related to moving mechanisms, the work of a dispatcher).

Application during pregnancy and lactation

The use of Oxolin during pregnancy and during breastfeeding is possible if the expected benefit outweighs the potential risks.

Drug interactions

No significant drug interactions between Oxolin and other drugs / substances have been identified.

Analogs

Oxolin analogs are: Alpizarin, Acyclovir, Aldara, Acigerpin, Acyclostad, Vartek, Bonafton, Vivorax, Gervirax, Gerpferon, Devirs, Imiquimod, Herperaks, Zovirax, Fenistil Penzivir.

Terms and conditions of storage

Keep out of the reach of children.

Shelf life:

Topical ointment - 3 years at temperatures up to 10 ° C;
Nasal ointment, ointment for external use - 2 years at a temperature of 5-15 ° C.

Terms of dispensing from pharmacies

Available without a prescription.

Reviews about Oxolin

Reviews about Oxolin are quite numerous, but contradictory. Some patients consider it to be a rather effective drug, use it successfully and recommend it to friends, including pregnant and lactating women, as well as infants. Other patients claim that Oxolin is an absolutely useless drug, referring to their own negative experience with its use.

It should be noted that side effects during the application of Oxolin, excluding a temporary burning sensation, practically do not occur. Therefore, even if the drug does not work, the harm from its use will be minimal.

The price of Oxolin in pharmacies

The approximate price for Oxolin in the form of nasal ointment 0.25% is 35-60 rubles. (per tube 10 g), and in the form of an ointment for topical use 0.25% - 43-65 rubles. (per tube 10 g). The cost of an ointment for external use of 3% is approximately 295-329 rubles. (per tube 10 g).