Laferobion
Instructions for use:
- 1. Pharmacological action
- 2. Release form
- 3. Indications for use
- 4. Contraindications
- 5. Instructions for use and doses
- 6. Side effects
- 7. Storage conditions
Laferobion is an immunomodulatory drug with high antiviral activity, used in the treatment of various diseases.
pharmachologic effect
The active ingredient Laferobion has antiviral, antitumor and immunomodulatory effects, while being a recombinant human interferon does not have a toxic effect.
The maximum concentration of Laferobion is reached with subcutaneous or intramuscular injection after 4-10 hours.
Laferobion increases immunomodulatory activity, inhibits proliferation and growth of viruses in infected cells. According to reviews, Laferobion is effective and safe in the treatment of infants from various infectious diseases.
Release form
Laferobion is produced in the form:
- Rectal suppository (Laferobion suppositories) containing 1,000,000-500,000 IU of active ingredient. Excipients - ascorbic acid, tocopherol acetate, solid fat. 3 and 5 candles per pack;
- Powder for preparation of nasal solution in ampoules containing 100,000-18,000,000 IU of active ingredient.
Indications for the use of Laferobion
According to the instructions, Laferobion is used as part of the complex therapy of infections caused by:
- Hepatitis B virus, in severe and moderate forms;
- Mixed infections, viral or bacterial, including in infants up to 1 month;
- Herpes virus, including herpetic eye lesions, herpetic skin rashes, genital herpes, herpes zoster;
- Human papillomavirus.
Also Laferobion is used in the complex therapy of multiple sclerosis and oncological diseases:
- Tumors of various localization, including cancer of the bladder, ovary, kidney, breast;
- Melanomas of the skin and eyes;
- Kaposi sarcomas;
- Multiple myeloma;
- Other malignant tumors of various localization.
Contraindications
According to the instructions, Laferobion is contraindicated for:
- Intolerance to the active substance - interferon, as well as other components of the drug,
- Severe kidney and liver diseases;
- Severe cardiovascular disease;
- Suppression of the myeloid germ of hematopoiesis;
- Diseases of the thyroid gland;
- Epilepsy and other diseases of the central nervous system;
Laferobion is contraindicated for use during pregnancy and lactation due to the lack of necessary research.
Instructions for the use of Laferobion and doses
Suppositories Laferobion are used rectally. Usually the course of treatment is 10 days. With human papillomavirus infection, precancerous diseases of the cervix, bacterial, viral and mixed infections and urogenital mix infections, sexually transmitted infections, one suppository Laferobion 1.5 million IU is usually prescribed every 12 hours.
For children, Laferobion is prescribed as part of complex therapy, one candle Laferobion 150 thousand IU every 12 hours. The average course duration is 5 days. In the treatment of acute respiratory viral infections, pneumonia of various etiologies and meningitis, one course is usually sufficient. For the treatment of infections caused by the Epstein-Barr virus, an increase in the dosage and duration of the course is required.
A solution of Laferobion in ampoules is used intramuscularly, intravenously, intradermally, subcutaneously, intravesically, intraperitoneally, rectally and intranasally, subconjunctivally.
In the treatment of acute respiratory viral infections in children, Laferobion 100,000 IU / ml is used intranasally, 4-6 drops in each nasal passage up to 6 times a day for 3-5 days, for newborns Laferobion is used at 20,000-50,000 IU / ml. You can also use cotton wool soaked in a solution of Laferobion in ampoules up to 8 times a day.
In the treatment of acute intestinal infections in children, Laferobion is used rectally at a dose of 10,000 IU / kg. In the treatment of peritonitis, purulent-septic diseases, multiple abdominal abscesses, Laferobion is used in ampoules intravenously, 2-4 million IU once a day, but no more than 12-16 million IU per course.
Treatment of children with Laferobion for other diseases is determined individually by the doctor, depending on the age and course of the disease.
Side effects
When using Laferobion, the resulting side effects usually disappear after the end of treatment. According to reviews, Laferobion can cause:
- Chills;
- Sleep disturbance;
- Fatigue;
- Sweating;
- Increased body temperature;
- Myalgia;
- Headache;
- Arthralgia;
- Lethargy.
To reduce these symptoms when using Laferobion, the use of paracetamol is recommended.
With prolonged therapy with Laferobion, according to the instructions, there may be:
- Arthralgia;
- Dizziness;
- Increased anxiety or drowsiness;
- Alopecia;
- Parasthesia;
- Tachycardia;
- Ataxia;
- Hot flashes;
- Cough;
- Leuko- and thrombocytopenia;
- Vomiting;
- Skin rash or itching;
- Herpetic lesions.
Much less often, according to reviews of Laferobion, anxiety and depressive conditions, nosebleeds and confusion occur.
Storage conditions
Laferobion is available without a prescription. Shelf life is 2 years. The diluted solution can be stored in the refrigerator for no more than a day.
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
