Ismigen - Instructions For The Use Of Tablets, Reviews, Price, Analogues

2024 Author: Rachel Wainwright | [email protected]. Last modified: 2023-12-15 07:39

Ismigen

Ismigen: instructions for use and reviews

1. 1. Release form and composition
2. 2. Pharmacological properties
3. 3. Indications for use
4. 4. Contraindications
5. 5. Method of application and dosage
6. 6. Side effects
7. 7. Overdose
8. 8. Special instructions
9. 9. Application during pregnancy and lactation
10. 10. Use in childhood
11. 11. Drug interactions
12. 12. Analogs
13. 13. Terms and conditions of storage
14. 14. Terms of dispensing from pharmacies
15. 15. Reviews
16. 16. Price in pharmacies

Latin name: Ismigen

ATX code: L03AX

Active ingredient: Bacterial lysates [Staphylococcus aureus, Streptococcus pyogenes, Streptococcus viridans, Streptococcus pneumoniae, Klebsiella pneumoniae, Klebsiella ozaenae, Haemophilus influenzae b, Neisseria catarrhalis pneumoniae] (Bacterial lysates, Streptoccus pneumoniae, Klebsiella pneumoniae, Neisseria catarrhalis Klebsiella ozaenae, Haemophilus influenzae b, Neisseria catarrhalis])

Manufacturer: NIZHFARM AO (Russia)

Description and photo update: 19.10.2018

Prices in pharmacies: from 352 rubles.

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Ismigen is a combined immunostimulating drug of bacterial origin.

Release form and composition

Ismigen's dosage form - sublingual tablets: light cream with brown blotches, flat-cylindrical, with a risk, with a weak specific mint aroma (10 pcs. In blisters, in a cardboard box 1 or 3 packs).

Composition of 1 tablet:

• active substance: lysates of bacteria, including Streptococcus viridans, Staphylococcus aureus, Streptococcus pyogenes, Streptococcus pneumoniae (types - TY3 / EQ14, TY1 / EQ11, TY2 / EQ22, TY8 / EQ23, TY5 / EQ15, TY47 / EQ24ella), KY5 / EQ15, TY47 / EQ24ella pneumoniae, Neisseria catarrhalis, Haemophilus influenzae b - 7 mg;
• auxiliary components: mint flavor - 0.8 mg; glycine - 43 mg (as part of the bacterial lysate); calcium hydrogen phosphate dihydrate - 35 mg; microcrystalline cellulose - 150 mg; magnesium stearate - 3 mg; colloidal silicon dioxide - 10 mg; ammonium glycyrrhizinate - 1.2 mg.

Pharmacological properties

Pharmacodynamics

Ismigen is a combined immunostimulating drug of bacterial origin for sublingual (sublingual) administration, which is a multivalent antigenic complex, which includes lysates of bacteria - the most common causative agents of respiratory infections. It has a specific vaccination and non-specific immunostimulating effect.

The drug acts on various links of the immune system. Stimulates systemic immune, humoral immune and local cellular responses. Activates phagocytosis, increases the number of immunocompetent cells and increases the content of lysozyme in saliva.

Increases the metabolic and functional activity of macrophages (including alveolar) and polymorphonuclear leukocytes; stimulates the secretion of prostaglandin E2 by macrophage-monocytic cells; reduces the concentration of serum IgE; activates natural killers; inhibits the synthesis of IL-4, IL-12; stimulates the release of anti-inflammatory cytokines; increases the concentration of secretory immunoglobulin IgA in saliva, serum immunoglobulins IgA, IgG, IgM.

As a result of the application of Ismigen, the severity, frequency and duration of acute infections of the respiratory tract are reduced; relief and leveling of concomitant symptoms (cough, fever, shortness of breath) occurs; the need for antibacterial and anti-inflammatory treatment is reduced. In the presence of chronic diseases of the respiratory tract, the drug prevents the appearance of an exacerbation.

The lysates included in the Ismigen tablets are obtained by mechanical action.

Indications for use

• infections of the upper and lower respiratory tract in acute and subacute course: otitis media, bronchitis, pharyngitis, tonsillitis, rhinitis, laryngitis, sinusitis, including complications after influenza (along with other drugs);
• chronic bronchitis, recurrent upper / lower respiratory tract infections (prevention of exacerbations).

Contraindications

• age up to 3 years;
• pregnancy and lactation;
• individual intolerance to the components of the drug.

Instructions for the use of Ismigen: method and dosage

The tablets should be taken sublingually on an empty stomach (until completely dissolved under the tongue; do not swallow, chew, or dissolve).

The daily dose is 1 tablet.

Recommended application scheme:

• subacute / acute infections of the upper and lower respiratory tract - at least 10 days (until the symptoms of the disease disappear);
• recurrent infectious processes of the upper and lower respiratory tract, exacerbation of chronic respiratory diseases (prevention) - 3 cycles of 30 days, including 10 days of taking Ismigen and a break of 20 days; preventive courses can be carried out no more than 1–2 times a year.

If you accidentally skip the next dose, you should not double the next one.

Side effects

Adverse reactions develop in very rare cases (<0.01%):

• skin: folliculitis, impetiginous dermatitis, urticaria;
• others: inflammation of the salivary gland, acute laryngitis, rhinitis.

Overdose

There is no information on overdose cases.

special instructions

For children 3–6 years old, for complete dissolution of the tablet in the oral cavity, control must be established daily.

Application during pregnancy and lactation

The drug is contraindicated for use during pregnancy and lactation.

Pediatric use

Ismigen is not assigned to children under 3 years old.

Drug interactions

There is no information on possible drug interactions with other substances / drugs.

According to the instructions, Ismigen can be used in combination with other drugs prescribed for the treatment of respiratory diseases in acute and chronic course.

Analogs

Ismigen's analogues are: Relief, Broncho-munal, Irs-19.

Terms and conditions of storage

Store at temperatures up to 25 ° C. Keep out of the reach of children.

The shelf life is 3 years.

Terms of dispensing from pharmacies

Dispensed by prescription.

Reviews about Ismigen

Reviews about Ismigen are mostly positive. Its high efficiency is noted both in the treatment of throat diseases and for the purpose of prevention, especially during epidemics.

Ismigen price in pharmacies

The price for Ismigen is approximately 450–550 or 1100–1360 rubles (for 10 or 30 tablets per pack, respectively).

Ismigen: prices in online pharmacies

Drug name Price Pharmacy

Ismigen 7 mg tablets sublingual 10 pcs. 352 r Buy

Ismigen tablets sublingual. 7mg 10 pcs. 506 RUB Buy

Ismigen 7 mg tablets sublingual 30 pcs. 1019 RUB Buy

Ismigen tablets sublingual. 7mg 30 pcs. 1218 RUB Buy

Maria Kulkes Medical journalist About the author

Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".

Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!