Gonadotropin

2024 Author: Rachel Wainwright | [email protected]. Last modified: 2023-12-15 07:39

Instructions for use:

1. Pharmacological action
2. Release form
3. Indications for use
4. Contraindications to use
5. Instructions for use
6. Side effects
7. Storage conditions

Prices in online pharmacies:

from 342 rub.

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Chorionic gonadotropin is a hormonal drug that is secreted from the urine of pregnant women. It is widely used for the prevention and treatment of infertility, stimulates ovulation in women and spermatogenesis in men.

pharmachologic effect

Chorionic gonadotropin is a hormone secreted by the placenta of a woman during pregnancy. Refers to gonadotropic hormones, has differences in amino acid sequence.

The hormone gonadotropin is released from the first weeks of pregnancy, which is used in early pregnancy tests. The amount of the hormone increases sharply in a woman's body in the first 11 weeks of pregnancy, and then gradually decreases. A decrease in the hormone in the first trimester of pregnancy may indicate a possible spontaneous miscarriage or ectopic pregnancy.

The presence of human gonadotropin in men and non-pregnant women indicates hormonal disorders or malignant tumors.

The drug Chorionic Gonadotropin has a follicle-stimulating and gonadotropic (mainly luteinizing) effect, stimulating ovulation, spermatogenesis, the development of genitals and the synthesis of sex hormones in the ovaries.

Release form

Gonadotropin is available as a sterile white powder for intramuscular injection.

The set includes 3 or 5 vials, as well as ampoules for preparing injections with sodium chloride solution. Each 5 ml bottle contains 500 U, 1000 U, 1500 U or 2000 U of the hormone.

Indications for the use of Gonadotropin

Human gonadotropin is widely used to treat sexual dysfunctions in men and women, which are associated with pituitary insufficiency and hypofunction of the gonads. Also, the indication is a decrease in the function of the gonads, which is caused by a violation of the activity of the hypothalamus and pituitary gland, Simmonds disease, hypogonadotropic hypogonadism with signs of eunuchoidism, panhypopituitarism of any etiology, Sheehan's syndrome and others.

Indications for treatment with Gonadotropin in women are:

Menstrual irregularities;
Infertility, which is associated with a lack of ovulation, hormonal disorders or deficiency of the corpus luteum;
Ovarian dysfunction;
Dysmenoria;
Miscarriage and the threat of miscarriage;
Dysfunctional uterine bleeding that occurs in women of childbearing age.

Human gonadotropin is also widely used to treat boys and men in cases of:

Genetic disorders associated with underdevelopment of the external genital organs;
Sexual infantilism or underdevelopment;
With cryptorchidism (the absence of one or two testicles in the scrotum);
With obesity caused by dysfunction of the sex glands;
With growth and development delay caused by dysfunction of the pituitary gland.

Contraindications for use

Hypersensitivity to drug components;
Various types of tumors, including the pituitary and gonads;
Congenital or postoperative absence of the sex glands;
Ovarian cancer;
Early onset of menopause;
Lactation period;
Obstruction of the fallopian tubes.

According to reviews of Gonadotropin, the drug should be used with caution in adolescence, with chronic renal failure, thrombophlebitis and ischemic heart disease.

Instructions for use

The hormone Gonadotropin is prescribed only intramuscularly, diluting it immediately before injection.

For women:

For the induction of ovulation, superovulation (when carrying out assisted reproductive measures) is usually prescribed a single injection of the drug, 5000-10000 U;
With the habitual miscarriage or the threat of spontaneous miscarriage, 10,000 units are administered on the first day of treatment, then 5,000 units are administered 2 times a week. Course - up to 14 weeks of pregnancy from the moment of diagnosis;
To stimulate the function of the corpus luteum, treatment is carried out on the 3.6 and 9 days after ovulation (1500-5000 IU once).

For men and boys:

With delayed sexual development in boys, treatment takes place within 3 months, once a week (3000-5000 ME);
In the treatment of sexual dysfunctions in men - 1 time a day 2-3 times a week (500-2000 units). The course is calculated individually from 1.5 to 3 months;
With hypogonadotropic hypogonadism - once a week in combination with menotropins (1500-6000 U);
For the diagnosis of cryptorchidism and anorchism - 5000 U once.

Side effects

In men, when using Gonadotropin, edema may occur, the sensitivity of the nipples of the mammary glands will increase, the number of sperm in the ejaculate will decrease and the testicles in the inguinal canal may increase.

Ovarian hyperstimulation syndrome may develop in women during fertility treatment with the hormone Gonadotropin.

According to reviews of Gonadotropin, during the treatment period, allergic reactions may occur, fatigue may increase, irritability, anxiety and depression may appear.

It should be noted that long-term use of the drug for cryptorchidism can lead to degeneration of the gonads, and in adolescent boys, premature puberty is possible. Also, with prolonged use of the drug, the development of antibodies and multiple pregnancy is possible.

In women, after discontinuation of the Gonadotropin drug within the first seven days, erroneous results of pregnancy tests are possible.

Storage conditions

Gonadotropin is classified as a List B drug and is dispensed in pharmacies only with a doctor's prescription. Storage - at a temperature not exceeding 20 ° С.

Gonadotropin: prices in online pharmacies

Drug name

Price

Pharmacy

Chorionic gonadotropin 500 IU lyophilisate for preparation of a solution for intramuscular administration complete with a solvent 1 ml 5 pcs.

342 r

Buy

Chorionic gonadotropin lyoph. for prigot. solution for intramuscular injection. 500ME 5ml 5 pcs.

421 r

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Chorionic gonadotropin 1000 IU lyophilisate for preparation of a solution for intramuscular administration complete with a solvent 1 ml 5 pcs.

659 r

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Reviews Chorionic gonadotropin

659 r

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Chorionic gonadotropin lyoph. for prigot. solution for i / m. 1000ME 5ml 5 pcs.

674 r

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Chorionic gonadotropin 1500 IU lyophilisate for preparation of a solution for intramuscular administration complete with a solvent 5 ml 5 pcs.

1039 RUB

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Chorionic gonadotropin 5000 IU lyophilisate for preparation of a solution for intramuscular administration 5 ml 5 pcs.

2607 RUB

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Chorionic gonadotropin lyoph. prigot. solution of intramuscular injection 5000 IU fl. 5ml No. 5 (with sodium solution chl-d 9 mg / ml amp. 1 ml No. 5)

RUB 2724

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Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!