Vicks Active Sinex
Vicks Active Sinex: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. In case of impaired renal function
- 12. Drug interactions
- 13. Analogs
- 14. Terms and conditions of storage
- 15. Terms of dispensing from pharmacies
- 16. Reviews
- 17. Price in pharmacies
Latin name: Vicks Active Sinex
ATX code: R01AA05
Active ingredient: oxymetazoline (Oxymetazoline)
Producer: Procter & Gamble Manufacturing, GmbH (Germany)
Description and photo update: 2019-11-07
Prices in pharmacies: from 209 rubles.
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Vicks Active Sinex is a vasoconstrictor, decongestant agent for local use in ENT practice; α-adrenergic agonist.
Release form and composition
The drug is produced in the form of a nasal spray 0.05%: a transparent, without visible inclusions, colorless or with a yellow tint solution with a characteristic odor (15 ml each in a dark glass bottle, 1 bottle in a cardboard box and instructions for use of Vicks Active Sinex).
100 ml of solution contains:
- active substance: oxymetazoline hydrochloride - 50 mg;
- additional components: potassium acesulfame, sorbitol 70%, chlorhexidine bigluconate 20% solution, benzalkonium chloride 50% solution, disodium edetate, sodium citrate dihydrate, cineole, L-carvone, sodium hydroxide solution 0.1 M, citric acid anhydrous, tyloxapol, leaf juice aloe tree, levomenthol, distilled water.
Pharmacological properties
Pharmacodynamics
Oxymetazoline belongs to the group of topical α-adrenostimulants. The drug has a vasoconstrictor effect. When administered intranasally, the active substance helps to reduce the swelling of the mucous membrane of the upper respiratory tract, providing relief of nasal breathing, opening the mouths of the paranasal sinuses and the auditory tube. The effect of the drug is observed 5 minutes after administration and lasts for 8-12 hours.
Pharmacokinetics
Oxymetazoline, when applied topically, is practically not absorbed into the systemic circulation.
Indications for use
Vicks Active Sinex is recommended for use to facilitate nasal breathing against the background of the following lesions:
- colds or viral infections of the upper respiratory tract;
- sinusitis and rhinitis of any genesis.
Contraindications
Absolute:
- condition after transsphenoidal hypophysectomy;
- atrophic (dry) rhinitis;
- angle-closure glaucoma;
- a history of instructions on surgical interventions on the dura mater;
- age up to 6 years;
- pregnancy and the period of breastfeeding;
- combined use with monoamine oxidase (MAO) inhibitors, as well as a period of two weeks before the start of their intake and after their withdrawal;
- hypersensitivity to the components of the product.
Relative (using Vicks Active Sinex nasal spray is recommended with caution):
- diseases of the cardiovascular system: chronic heart failure (CHF), ischemic heart disease (IHD), arrhythmias, tachycardia, arterial hypertension;
- dysfunction of the thyroid gland: hyperthyroidism;
- disorders of carbohydrate metabolism: diabetes mellitus;
- chronic renal failure;
- pheochromocytoma;
- porphyria;
- hyperplasia of the prostate: urinary retention;
- concomitant treatment with tricyclic antidepressants and bromocriptine.
Vicks Active Sinex, instructions for use: method and dosage
Vicks Active Sinex is used intranasally.
The spray is recommended to be administered 2-3 times a day: children 6-10 years old - 1 injection, adults, adolescents and children over 10 years old - 1-2 injections into each nasal passage. The maximum frequency of administration is 3 times a day.
It is not recommended to carry out drug therapy for more than 7 days. In the case of prolonged and frequent use of Vicks Active Sinex spray, the feeling of difficulty in nasal breathing may reappear or worsen. If such symptoms develop, you should stop using the product and consult a doctor for advice.
When injecting, do not throw your head back, and it is also not recommended to spray the spray while lying down.
Side effects
- local reactions: sometimes - dryness or burning of the nasal mucosa, sneezing, dryness in the mouth and throat, an increase in the amount of secretion released from the nose; in rare cases - a strong feeling of nasal congestion (reactive hyperemia) after the end of the effect of using Vicks Active Sinex;
- systemic reactions: dizziness, headache, palpitations, increased blood pressure (BP), tachycardia, sedation, irritability, increased anxiety, sleep disturbances (in children), insomnia, nausea, visual impairment (when sprayed in the eyes), exanthema …
The preservative benzalkonium chloride included in the product can cause swelling of the nasal mucosa. If you suspect the development of this phenomenon, it is necessary to cancel Vicks Active Sinex and start using the drug that does not contain preservatives.
Overdose
Oxymetazoline overdose symptoms: sweating, pallor, lethargy, cyanosis, decreased body temperature, nausea, vomiting, drowsiness, anxiety, anxiety, pupillary constriction / dilation, fever, convulsions, hallucinations, palpitations, increased / decreased blood pressure, arrhythmia, depression breathing (up to its stop), coma, cardiac arrest.
The appearance of these reactions requires symptomatic therapy. In case of accidental oral administration of the spray, gastric lavage is performed and activated charcoal is taken.
special instructions
Do not use Vicks Active Sinex spray in recommended doses without a doctor's prescription for more than 7 days.
If there is an increase in the symptoms of the disease or it is not possible to achieve an improvement in the condition within 3 days of treatment with the drug, you should consult your doctor.
It is required to beware of contact with the spray in the eyes.
To prevent the spread of infection, the drug must be used individually.
Influence on the ability to drive vehicles and complex mechanisms
After prolonged use of drugs containing oxymetazoline for the common cold in doses exceeding the recommended doses, there is a possibility of systemic effects on the cardiovascular and nervous system. In such cases, it is recommended to drive vehicles and other complex moving machinery with extreme caution.
Application during pregnancy and lactation
In preclinical studies on animals, the direct / indirect effect of the drug on the course of pregnancy, childbirth, development of the embryo / fetus has not been established. There are no clinical data on exposure to oxymetazoline during pregnancy, therefore the use of Vicks Active Sinex in pregnant women is contraindicated.
Whether oxymetazoline hydrochloride is excreted in breast milk is unknown. The use of Vicks Active Sinex during breastfeeding is contraindicated.
Pediatric use
It is contraindicated to use Vicks Active Sinex for children under 6 years old.
With impaired renal function
In the presence of chronic renal failure, drug therapy should be carried out with caution.
Drug interactions
- MAO inhibitors (including the period within 14 days after the end of their use), tricyclic antidepressants: the risk of increased blood pressure is aggravated;
- other vasoconstrictor drugs: the threat of the development of undesirable effects increases;
- local anesthetic drugs: their absorption is slowed down and the effect is prolonged.
Analogs
Analogs of Vicks Active Sinex are Oxymetazoline, Otrivin Oxy, Nazivin, Afrin Extro, Nazivin Sensitiv, Afrin, Oxymetazoline-Akrihin, Nazo-spray, Rinostop Extra, Oxyphrin, etc.
Terms and conditions of storage
Store out of the reach of children, at a temperature not exceeding 25 ° C.
The shelf life is 3 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Vicks Active Sinex
Reviews about Vicks Active Sinex found on medical websites are quite diverse. Most patients consider the drug to be an effective, easy-to-use remedy for the common cold. It is noted that the spray quickly relieves swelling of the mucous membrane and nasal congestion, restores or facilitates nasal breathing within 10 minutes after administration, and retains its effect for 8-12 hours. Almost everyone likes the pleasant, refreshing scent of a spray.
At the same time, many patients indicate that with frequent and prolonged use, such drugs can lead to atrophy and drying of the nasal mucosa, as well as cause addiction and dependence. As a result, it is recommended to use Vicks Active Sinex only in the first 2-3 days of the disease, and in the following days, in case of insufficient decrease in the severity of symptoms, be sure to contact an ENT doctor.
There are reviews in which they complain about the complete lack of effect from the drug treatment or the short-term effect of Vicks Active Sinex, as well as the development against the background of its use of adverse reactions in the form of burning of the nasal mucosa after injection, headache, dizziness, allergic reactions. Many patients find the drug overpriced.
The price of Vicks Active Sinex in pharmacies
The price of Vicks Active Sinex, nasal spray 0.05%, can be 230-280 rubles. per bottle, 15 ml.
Vicks Active Sinex: prices in online pharmacies
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Drug name Price Pharmacy |
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Vicks Active Sinex 0.05% nasal spray 15 ml 1 pc. 209 RUB Buy |
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
