Took
Instructions for use:
- 1. Release form and composition
- 2. Indications for use
- 3. Contraindications
- 4. Method of application and dosage
- 5. Side effects
- 6. Special instructions
- 7. Drug interactions
- 8. Terms and conditions of storage
Prices in online pharmacies:
from 32 rubles.
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I took - a combined preparation containing a non-narcotic analgesic, a myotropic antispasmodic and M-anticholinergic drugs as active substances. It has analgesic, antipyretic and mild anti-inflammatory effects.
Release form and composition
- solution for intravenous and intramuscular administration: transparent, yellowish (5 ml in dark glass ampoules, 5 ampoules in a pallet, 1 pallet in a cardboard box);
- tablets: round, flat, with beveled edges, pale yellow, with a line on one side and MICRO engraving on the other (10 pcs. in blisters or strips, in a cardboard box 1, 2 or 10 blisters / strips).
Active ingredients in 1 ml of solution:
- metamizole sodium (analgin) - 500 mg;
- pitofenone hydrochloride - 2 mg;
- fenpiverinium bromide - 0.02 mg.
Auxiliary components: hydrochloric acid, water for injection.
Active ingredients in 1 tablet:
- metamizole sodium - 500 mg;
- pitofenone hydrochloride - 5 mg;
- fenpiverinium bromide - 0.1 mg.
Auxiliary components: methylhydroxybenzoate, povidone, purified talc, corn starch (anhydrous), magnesium stearate, lactose.
Indications for use
- relief of mild and moderate pain syndrome with spasms of smooth muscles of internal organs: intestinal colic, renal colic, biliary colic, spasm of the ureter and bladder, postcholecystectomy syndrome, biliary dyskinesia, algomenorrhea;
- relief of pain syndrome after diagnostic procedures and surgical interventions (as an aid);
- short-term symptomatic therapy: neuralgia, sciatica, arthralgia, myalgia.
Contraindications
- chronic heart failure in the stage of decompensation;
- tachyarrhythmias;
- stable and unstable angina pectoris;
- megacolon;
- intestinal obstruction;
- oppression of bone marrow hematopoiesis;
- acute intermittent porphyria;
- angle-closure glaucoma;
- severe liver and / or kidney dysfunction;
- hyperplasia of the prostate gland, accompanied by clinical manifestations;
- deficiency of glucose-6-phosphate dehydrogenase;
- collaptoid states;
- children under 3 months (or body weight less than 5 kg) - for injection solution, up to 5 years - for tablets;
- first trimester and last 6 weeks of pregnancy;
- lactation (or feeding should be stopped);
- simultaneous use of X-ray contrast agents and colloidal blood substitutes;
- hypersensitivity to pyrazolone derivatives (butadione) and other components of the drug.
Carefully:
- tendency to arterial hypotension;
- impaired liver or kidney function;
- bronchial asthma;
- tendency to bronchospasm;
- age up to 18 years;
- a history of hypersensitivity to non-steroidal anti-inflammatory drugs or non-narcotic analgesics (including the aspirin triad).
Method of administration and dosage
Solution for intravenous and intramuscular administration
In this dosage form, Bral is intended for intramuscular (i / m) and intravenous (i / v) injections.
For adults and adolescents over 15 years of age with acute severe colic, the drug is administered slowly (within 2 minutes) intravenously in a dose of 2 ml, if necessary, a repeated dose is administered after 6–8 hours.
Intramuscularly appoint 2 ml 2 times a day.
Recommended single doses for children, depending on their age and body weight:
- 12-15 years (or 46-53 kg): IV or IM - 0.8-1 ml;
- 8–12 years old (or 31–45 kg): IV - 0.5–0.6 ml, IM - 0.6–0.7 ml;
- 5-7 years (or 24-30 kg): i / v - 0.3-0.4 ml, i / m - 0.4-0.5 ml;
- 3-4 years (or 16-23 kg): i / v - 0.2-0.3 ml, i / m - 0.3-0.4 ml;
- 1-2 years (or 9-15 kg): i / v - 0.1-0.2 ml, i / m - 0.2-0.3 ml;
- 3-11 months (or 5-8 kg): only i / m - 0.1-0.2 ml.
If necessary, repeated administration of the drug in the same doses may be prescribed.
The solution should be warmed in the hand before injection.
Took incompatible in the same syringe with other drugs.
The duration of parenteral therapy is no more than 5 days.
Pills
In this dosage form, the drug should be taken orally, preferably after meals.
Recommended single doses:
- adults and adolescents over 15 years of age: 1-2 tablets;
- adolescents 13–15 years old: 1 tablet;
- children 8–12 years old: ¾ tablets;
- children 5–7 years old: ½ tablet.
The frequency of admission is 2-3 times a day.
The duration of treatment is no more than 5 days.
An increase in the dose or duration of therapy is possible only on the recommendation of a doctor and under his supervision.
Side effects
When taking Bral in therapeutic doses, the drug is usually well tolerated.
In rare cases, the following side effects are noted:
- allergic and dermatological reactions: skin rash, itching, urticaria, angioedema, anaphylactic shock, malignant exudative erythema, toxic epidermal necrolysis;
- from the digestive system: dry mouth, burning sensation in the epigastric region;
- from the nervous system: headache;
- on the part of the cardiovascular system: dizziness, tachycardia, decreased blood pressure, cyanosis;
- from the respiratory system: with a tendency to bronchospasm - an attack of bronchospasm;
- from the hematopoietic system: leukopenia, thrombocytopenia, agranulocytosis (unmotivated fever, difficulty swallowing, sore throat, stomatitis, chills, symptoms of proctitis or vaginitis);
- on the part of the urinary system: usually when taking high doses or for a long time - anuria, oliguria, proteinuria, urine staining red, interstitial nephritis, difficulty urinating;
- local reactions: with intramuscular injection - infiltrates at the injection site;
- others: paresis of accommodation, decreased sweating.
special instructions
Took should not be used to relieve acute abdominal pain until the cause of their occurrence is established.
During treatment, you should not drink alcoholic beverages, it is recommended to refrain from performing potentially hazardous activities, including driving a car.
In the form of a solution, Bral is prescribed in emergency situations and in cases where ingestion is impossible (for example, in case of impaired absorption from the gastrointestinal tract).
Intravenous administration should be done slowly, with the patient lying down, under the control of blood pressure, respiratory rate and heart rate.
Particular care must be taken if it is necessary to administer a solution in a dose of 2 ml or more, since a sharp decrease in blood pressure is possible.
With long-term treatment (more than 5 days), it is necessary to monitor the functional state of the liver and the picture of peripheral blood.
Drug interactions
- other non-narcotic analgesics: toxic effects are mutually reinforced;
- tricyclic antidepressants, oral contraceptives, allopurinol: the metabolism of metamizole sodium in the liver is disrupted, its toxicity increases;
- butyrophenones, H 1 -histamine blockers, phenothiazines, amantadine, quinidine: the M-cholinolytic effect of fenpiverinium bromide is enhanced;
- ethanol: the effects are mutually reinforcing;
- tranquilizers, sedatives: the analgesic effect of metamizole sodium is enhanced;
- indirect anticoagulants, hypoglycemic drugs, glucocorticosteroids, indomethacin: the severity of their action increases;
- H 2 -histamine blockers, codeine, propranolol: the effect of Bral is enhanced;
- cyclosporine: its concentration in the blood decreases;
- chlorpromazine or other phenothiazine derivatives: severe hyperthermia may develop;
- barbiturates, inducers of liver microsomal enzymes (including phenylbutazone): the effect of metamizole sodium is weakened;
- cytostatics, thiamazole: the risk of developing leukopenia increases.
In the form of a solution for injection, Took is pharmaceutically incompatible with other drugs.
If necessary, the simultaneous use of any other drug, you should consult your doctor.
Terms and conditions of storage
Keep out of reach of children, protected from light at temperatures up to 25 ° C.
The shelf life of the solution is 3 years, of the tablets - 5 years.
Took: prices in online pharmacies
|
Drug name Price Pharmacy |
|
I took 10 tablets. 32 RUB Buy |
|
I took 20 tablets. RUB 80 Buy |
|
I took 20 tablets. 83 rbl. Buy |
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I took 100 tablets. 288 r Buy |
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I took 100 tablets. 310 RUB Buy |
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
