Benzydamine-Akrikhin - Instructions For Using The Spray, Reviews, Price

2024 Author: Rachel Wainwright | [email protected]. Last modified: 2023-12-15 07:39

Benzydamine-Akrikhin

Benzydamine-Akrikhin: instructions for use and reviews

1. 1. Release form and composition
2. 2. Pharmacological properties
3. 3. Indications for use
4. 4. Contraindications
5. 5. Method of application and dosage
6. 6. Side effects
7. 7. Overdose
8. 8. Special instructions
9. 9. Application during pregnancy and lactation
10. 10. Use in childhood
11. 11. Use in the elderly
12. 12. Drug interactions
13. 13. Analogs
14. 14. Terms and conditions of storage
15. 15. Terms of dispensing from pharmacies
16. 16. Reviews
17. 17. Price in pharmacies

Latin name: Benzydamine-Akrihin

ATX code: A01AD02

Active ingredient: benzydamine (Benzydamine)

Producer: Flumed-Farm KP, LLC (Republic of Moldova)

Description and photo update: 2020-11-06

Prices in pharmacies: from 207 rubles.

Buy

Benzydamine-Akrikhin is a drug for local use in dentistry and ENT practice; has anti-inflammatory and analgesic effects.

Release form and composition

The preparation is produced in the form of a spray for topical application metered (0.255 mg / dose): a colorless transparent solution with a characteristic mint odor [30 ml (176 doses) in a dark glass bottle equipped with a dispensing device with a spray nozzle and a transparent cap; in a cardboard box 1 bottle and instructions for use of Benzidamine-Akrikhin].

100 ml of spray contains:

• active substance: benzydamine hydrochloride - 150 mg;
• additional components: sodium bicarbonate, glycerol, methyl parahydroxybenzoate, saccharin, polysorbate-20, peppermint leaf oil, ethanol 96%, purified water.

Pharmacological properties

Pharmacodynamics

Benzydamine is a non-steroidal anti-inflammatory drug (NSAID) that belongs to the indazole group. The drug demonstrates anti-inflammatory and local analgesic effects, exhibits antiseptic activity against a wide range of pathogenic microorganisms. The mechanism of action of the drug is based on the stabilization of cell membranes and inhibition of prostaglandin production.

The antibacterial and specific antimicrobial action of the drug is carried out through its rapid passage through the membranes of microorganisms and further damage to cellular structures, disruption of metabolic processes in the cell and its lysis.

The active substance demonstrates antimicrobial action against Candida albicans, provides structural modifications to metabolic chains and the walls of fungal cells, thereby preventing the reproduction of the latter. This property of Benzydamine-Akrikhin allows it to be used for the treatment of inflammatory processes in the oral cavity, including lesions of infectious etiology.

Pharmacokinetics

When used topically, benzydamine is actively absorbed through the mucous membranes and quickly penetrates into tissues prone to inflammation. In the blood plasma, the active substance is detected in an amount insufficient for the manifestation of systemic effects.

The agent is excreted in the form of conjugation products or inactive metabolites, mainly through the kidneys.

Indications for use

Benzydamine-Akrikhin is recommended for the symptomatic treatment of pain syndrome of inflammatory lesions of the ENT organs and oral cavity (of various etiologies):

• tonsillitis, laryngitis, pharyngitis;
• glossitis, gingivitis, stomatitis (including after radiation and chemotherapy);
• calculous inflammation of the salivary glands;
• candidiasis of the oral mucosa (as part of complex therapy);
• periodontal disease;
• conditions after treatment / tooth extraction;
• conditions after surgery and trauma, such as a fractured jaw, tonsillectomy.

In the presence of inflammatory / infectious diseases that require systemic therapy, Benzydamine-Akrikhin is used in combination with other drugs.

Contraindications

Absolute:

• age up to 3 years;
• pregnancy;
• period of breastfeeding;
• hypersensitivity to any component of the product.

Relative (requires treatment with the drug with extreme caution):

• bronchial asthma, including indications in the history (due to the increased risk of developing bronchospasm);
• hypersensitivity to other NSAIDs or acetylsalicylic acid.

Benzydamine-Akrikhin, instructions for use: method and dosage

Spray Benzydamine-Akrikhin should be applied topically after meals.

One dose of the drug (1 injection) contains benzydamine hydrochloride in an amount of 0.255 mg.

Recommended single doses of Benzydamine-Akrikhin, depending on the age of the patients, with the frequency of injections 2-6 times a day:

• children from 3 to 6 years: 1 injection for every 4 kg of body weight, the maximum single dose is 4 injections;
• children from 6 to 12 years old: 4 shots;
• adolescents over 12 years old and adults (including elderly patients): 4–8 injections.

The recommended dose cannot be exceeded, the course of therapy should not be more than 7 days. If, after the full course of treatment, there is no improvement or new symptoms develop, you should consult a specialist.

Side effects

• allergic reactions: infrequently (more than 1/1000, but less than 1/100) - photosensitization; rarely (more than 1/10 000, but less than 1/1000) - itching, skin rash, hypersensitivity reactions (it is required to cancel the spray treatment and carry out the appropriate therapy prescribed by the doctor); extremely rare (less than 1/10 000) - laryngospasm, angioedema; with an unknown frequency (the available data do not allow us to establish the incidence of adverse events) - anaphylactic reactions;
• local reactions: rarely - dryness, burning sensation in the mouth; with an unknown frequency - a feeling of numbness localized in the oral cavity.

In case of an increase in the severity of any of the above adverse events or the occurrence of other adverse reactions, you should consult a doctor.

Overdose

There are currently no reports of drug overdose cases. If the spray is used as directed, overdose is unlikely. In case of accidental oral administration of the drug, the following symptoms may develop: anxiety, abdominal cramps, vomiting, fever, fear, hallucinations, tachycardia, convulsions, ataxia, respiratory depression.

The antidote has not been established; in this condition, symptomatic treatment should be carried out. It is required to induce vomiting or, under the supervision of a specialist, rinse the stomach using a gastric tube, provide medical supervision, carry out adequate hydration and supportive therapy.

special instructions

If in patients with ulcers of the mucous membrane of the oropharynx symptoms do not relieve after treatment with the drug for more than 3 days, it is necessary to consult a doctor, since sometimes the presence of ulcers of this localization may indicate a serious pathology.

Spray Benzydamine-Akrikhin includes parahydroxybenzoates, which can lead to the development of allergic reactions.

Influence on the ability to drive vehicles and complex mechanisms

Benzydamine-Akrikhin does not adversely affect the ability to carry out potentially hazardous activities, including driving vehicles.

Application during pregnancy and lactation

The drug is not prescribed to pregnant and lactating women.

Pediatric use

In children under 3 years of age, the use of the spray is contraindicated, in children 3 years of age and older, it is possible according to the dosage regimen.

Use in the elderly

Elderly patients do not need a dose adjustment of Benzydamine-Akrikhin.

Drug interactions

There are no studies of the interaction of benzydamine with other medicinal substances / drugs.

Analogs

Analogs of Benzydamine-Akrikhin are Bronflex, Anidak, Anidak forte, Tantum Verde, Anidak sept, Benzidamine, Vertum ENT, Zvezdochka ENT, Tantum Verde forte, Oralsept, etc.

Terms and conditions of storage

Store in its original packaging out of the reach of children at a temperature not exceeding 25 ° C.

The shelf life is 3 years.

Terms of dispensing from pharmacies

Available without a prescription.

Reviews about Benzidamine-Akrikhin

There are no reviews about Benzydamine-Akrikhin on specialized sites, as a result of this, it is impossible to really assess its effectiveness and disadvantages.

The price of Benzydamine-Akrikhin in pharmacies

The price of Benzydamine-Akrikhin in the form of a dosed topical spray (0.255 mg / dose) can be 210–230 rubles. per bottle of 30 ml.

Benzydamine-Akrikhin: prices in online pharmacies

Drug name Price Pharmacy

Benzydamine-Akrihin spray for local. approx. dosage. 0.255mg / dose vial 30ml (176 doses) 207 r Buy

Anna Kozlova Medical journalist About the author

Education: Rostov State Medical University, specialty "General Medicine".

Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!