Clindamycin - Instructions For Use, Indications, Doses, Reviews

2024 Author: Rachel Wainwright | [email protected]. Last modified: 2023-12-15 07:39

Clindamycin

Instructions for use:

1. 1. Pharmacological action
2. 2. Release form
3. 3. Indications for use
4. 4. Contraindications
5. 5. Instructions for use and doses
6. 6. Side effects
7. 7. Storage conditions

Prices in online pharmacies:

from 130 rubles.

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Clindamycin is a broad-spectrum antibiotic produced in various dosage forms for the treatment of infectious diseases. It is widely used in pediatrics.

pharmachologic effect

Clindamycin is a lincosamide antibiotic.

The active substance has a bacteriostatic effect when used in therapeutic doses, and in high doses it has a bactericidal effect on strains sensitive to Clindamycin. Clindamycin is widely used, including in pediatrics, for various diseases of the respiratory tract, soft tissues, joints and bones caused by:

• Propionibacterium;
• Eubacterium;
• Corynebacterium diphtheriae;
• Peptococcus;
• Clostrtidium tetani;
• Clostrtidium perfringens;
• Veillonella;
• Staphylococcus spp.;
• Fusobacterium spp. (with the exception of F.varium, which is resistant);
• Streptococcus spp.;
• Bacteroides spp;
• Bacillus anthracis;
• Peptostreptococcus spp..

According to the instructions for Clindamycin, most gram-negative aerobic bacteria, resistant strains of Staphylococcus aureus, Neisseria gonorrhoeae, Haemophilus influenzae and Neisseria meningitidis, as well as viruses and fungi (including yeast) are resistant.

Release form

Clindamycin is available as:

• Gelatin capsules with a purple body, containing white powder of 0.075 g (for children), 0.3 g and 0.15 g of clindamycin hydrochloride. 8 pieces in a blister;
• Transparent colorless 15% solution for intravenous injection, 150 mg of active ingredient in 1 ml. In ampoules of 2 ml, 4 ml and 6 ml;
• Flavored granules for the preparation of Clindamycin syrup for children, containing 75 mg of active ingredient in 5 ml. In bottles of 80 ml;
• 2% Clindamycin vaginal cream, in tubes of 40 g with 7 single applicators;
• White, cylindro-conical form of Clindamycin vaginal suppositories, 3 suppositories per pack;
• Homogeneous white gel Clindamycin for external use, in aluminum tubes of 15 g.

Indications for use

According to the instructions, Clindamycin is used for:

• Peritonitis;
• Osteomyelitis;
• Empyema of the pleura;
• Endometritis;
• Adnexitis;
• Purulent infections of the skin and soft tissues;
• Lung abscess;
• Pneumonia;
• Purulent wounds.

Clindamycin is also used in combination therapy for the prevention of peritonitis and intra-abdominal abscesses.

Clindamycin gel is used externally to treat acne.

Suppositories Clindamycin is used topically for vaginosis caused by microorganisms sensitive to the drug.

Contraindications

According to the instructions, Clindamycin is contraindicated in:

• Hypersensitivity to lincomycin or clindamycin;
• Severe violations of liver or kidney function;
• Myasthenia gravis;
• Bronchial asthma;
• Ulcerative colitis.

Clindamycin is not prescribed under the age of one month and for the elderly, it is prescribed with caution in case of a history of gastrointestinal tract diseases.

Clindamycin is contraindicated for use during pregnancy and lactation for oral and parenteral administration.

Intravaginal use of Clindamycin is possible only for strict indications.

Instructions for the use of Clindamycin and doses

The dose of Clindamycin and the choice of its dosage form depend on the disease, the course of the disease and age.

For severe infections and diseases of the abdominal cavity, Clindamycin is administered by injection according to the instructions. In mild forms, 1.2-1.8 g are usually administered per day, and in severe forms - 2.4-2.7 g, divided into 2-4 doses. Do not administer more than 600 mg of Clindamycin at a time.

Clindamycin is intravenously used for inflammation of the appendages of the uterus and peritoneum, which is localized in the pelvic region, every 8 hours for 0.9 g. Clindamycin is administered intravenously for at least four days, and then at least two days after the onset of improvement.

Clindamycin tablets are used after a clinical effect is achieved, every 6 hours, 450 mg until the completion of a two-week course of therapy.

Clindamycin tablets are also used for the treatment of mild to moderate infectious and inflammatory diseases. Adults are prescribed 150-450 mg every 6 hours for a period of at least 10 days.

For the treatment of cervical infections that cause chlamydia, Clindamycin tablets are used 4 times a day, 450 mg for 10-14 days.

In pediatrics, Clindamycin is most often used in the form of a syrup, for which 60 ml of water is added to the bottle with granules. The dose of the drug is calculated based on the body weight and age of the child. The daily dose for children from a month is 8-25 mg per 1 kg of body weight, divided into 3-4 doses. Children weighing up to 10 kg or less are prescribed half a teaspoon three times a day. Clindamycin tablets can be used from 8 years old with a weight of at least 25 kg.

For vaginal inflammation caused by bacteria sensitive to the drug, Clindamycin vaginal cream is prescribed. One full applicator is a single dose inserted into the vagina at bedtime. The course of treatment is at least a week.

Clindamycin gel is used externally for acne, applying to the affected area several times a day. The course of treatment is from two weeks to a month.

Suppositories Clindacin are intended for the treatment of urinary tract infections and the prevention of vaginal inflammation, and it is also used during preparation for various gynecological operations. Usually, the course of treatment with Clindamycin suppositories is three days, one suppository per day.

Clindamycin suppositories should not be used simultaneously with other vaginal medications, as well as with calcium gluconate, ampicillin, barbiturates and erythromycin. Clindamycin, when used simultaneously with drugs that block neuromuscular transmission, enhances their effect.

Side effects

Clindamycin has a variety of side effects.

After intravenous administration, a metallic taste, phlebitis, abscess may appear. After taking Clindamycin tablets - the phenomenon of esophagitis, abdominal pain, diarrhea, liver disease and jaundice.

Rarely enough, urticaria, reversible leukopenia, fever, Quincke's edema, neutropenia, thrombocytopenia, agranulocytosis, lowering blood pressure, weakness can occur.

When using Clindamycin suppositories - vaginitis, cervicitis or vulvovaginal irritation, and when using Clindamycin cream - minor skin allergic reactions.

Storage conditions

Clindamycin is classified as a Group B drug and is available on prescription.

Clindamycin: prices in online pharmacies

Drug name Price Pharmacy

Clindamycin 150 mg capsule 16 pcs. 130 RUB Buy

Clindamycin capsules 150mg 16 pcs. RUB 165 Buy

Clindamycin 2% vaginal cream 20 g 1 pc. 424 r Buy

Clindamycin 150 mg / ml solution for intravenous and intramuscular administration 2 ml 10 pcs. 549 r Buy

Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!