Asvitol
Instructions for use:
- 1. Release form and composition
- 2. Indications for use
- 3. Contraindications
- 4. Method of application and dosage
- 5. Side effects
- 6. Special instructions
- 7. Drug interactions
- 8. Terms and conditions of storage
Prices in online pharmacies:
from 20 rubles.
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Asvitol is a vitamin preparation that participates in the synthesis of steroid hormones, tissue regeneration, regulation of carbohydrate metabolism and oxidation-reduction processes, reduces vascular permeability, increases body resistance, reduces the need for pantothenic and folic acids, vitamins A, B1, B2 and E, replenishing increased the body's need for vitamin C in diseases accompanied by fever.
Release form and composition
Dosage form - chewable tablets: flat-cylindrical, from pinkish-orange to orange, interspersed, with a chamfer and risk, with a weak fruity odor (10 and 20 pcs. In blisters, in a cardboard box 1, 2 or 3 packages; 20, 30 and 50 pcs. in polymer cans, in a pack of cardboard 1 can).
Active ingredient: ascorbic acid, 1 tablet - 200 mg.
Auxiliary components: ethyl cellulose, magnesium stearate, sucrose (sugar), stearic acid, aspartame, low molecular weight povidone (low molecular weight medical polyvinylpyrrolidone), talc, orange flavor, sunset yellow dye.
Indications for use
Asvitol is a drug for the treatment and prevention of vitamin C hypo- and avitaminosis.
As part of complex therapy, a vitamin agent is used in the following cases:
- hemorrhagic diathesis, pulmonary, uterine, nose and other bleeding, including those caused by radiation sickness;
- increased mental and physical stress;
- dystrophy;
- bone fractures and sluggish healing wounds;
- overdose of anticoagulants;
- recovery period after long and / or severe illness.
Contraindications
Absolute:
- kidney stone disease;
- tendency to thrombosis;
- thrombophlebitis;
- diabetes;
- childhood;
- hypersensitivity to drug components.
Relative (diseases / conditions in which Asvitol should be used with extreme caution):
- sickle cell anemia;
- sideroblastic anemia;
- hemochromatosis;
- polycythemia;
- leukemia;
- thalassemia;
- progressive malignant diseases;
- renal failure;
- hyperoxalaturia;
- deficiency of glucose-6-phosphate dehydrogenase;
- pregnancy.
Method of administration and dosage
Asvitol should be taken orally after a meal, chewing a tablet and drinking it with a little water.
Recommended doses for adults:
- for medicinal purposes: 1-2 tablets 1-2 times a day, in some cases it is allowed to increase the daily dose up to 5 tablets;
- for preventive purposes: 1 tab. Once a day.
Side effects
- from the endocrine system: glucosuria, hyperglycemia;
- from the digestive system: nausea, stomach cramps, irritation of the gastrointestinal mucosa, diarrhea, vomiting;
- from the side of the cardiovascular system: thrombosis, when taking high doses of the drug - myocardial dystrophy, increased blood pressure, microangiopathy;
- from the urinary system: when using high doses - the formation of urinary stones from calcium oxalate, hyperoxalaturia;
- from the central nervous system: a feeling of fatigue, headache, with prolonged intake of high doses - sleep disturbances, increased excitability of the central nervous system;
- laboratory parameters: erythropenia, hypokalemia, hypoprothrombinemia, thrombocytosis, neutrophilic leukocytosis;
- allergic reactions: skin rashes; rarely - anaphylactic shock;
- others: a feeling of heat, hypervitaminosis, damage to the tooth enamel (especially with heavy consumption of chewable tablets); with long-term use of high doses - a violation of the exchange of zinc and copper, sodium and fluid retention.
special instructions
Ascorbic acid has a stimulating effect on the synthesis of corticosteroid hormones, therefore, during treatment, it is necessary to control blood pressure and adrenal function.
With prolonged use of Asvitol in high doses, it is possible to suppress the function of the insular apparatus of the pancreas, manifested by hyperglycemia and glucosuria. For this reason, patients with a high iron content in the body should be prescribed the drug in a minimum dose.
Ascorbic acid can aggravate the development of proliferating and intensely metastatic tumors.
Vitamin C can distort the results of various laboratory tests, including the level of bilirubin and glucose in the blood, the determination of the activity of transaminases and lactate dehydrogenase.
Pregnant and lactating women should take into account that in the II-III trimesters, the daily daily requirement for ascorbic acid is about 60 mg, during lactation - 80 mg. A woman's diet containing an adequate amount of vitamin C is sufficient to prevent deficiency in an infant (breastfeeding women are not advised to exceed the maximum need for ascorbic acid).
Drug interactions
With the simultaneous use of ascorbic acid:
- reduces the chronotropic effect of isoprenaline;
- reduces the therapeutic effect of antipsychotics that are derivatives of phenothiazine;
- reduces tubular reabsorption of amphetamine, tricyclic antidepressants;
- increases the total clearance of ethanol, which, in turn, decreases the concentration of ascorbic acid;
- increases the concentration in the blood of tetracyclines and benzylpenicillin;
- increases the excretion of iron when used concomitantly with deferoxamine;
- in a daily dose of 1 g increases the bioavailability of ethinyl estradiol;
- improves the absorption of iron preparations in the intestine (converts ferric iron to bivalent);
- with prolonged use or taken in high doses, it can disrupt the interaction of disulfiram with ethanol;
- in high doses enhances the excretion of mexiletine by the kidneys;
- slows down the excretion of acids by the kidneys;
- reduces the concentration of oral contraceptives in the blood;
- enhances the excretion of drugs with an alkaline reaction (including alkaloids);
- increases the risk of crystalluria with the use of short-acting salicylates and sulfonamides;
- reduces the effectiveness of indirect anticoagulants and heparin.
Primidone and barbiturates, in the case of simultaneous use, increase the excretion of ascorbic acid (AA) in the urine.
Alkaline drinks, fresh juices, oral contraceptives, and acetylsalicylic acid (ASA) reduce the absorption and assimilation of AA.
In addition, with the simultaneous use of ASA, its excretion decreases, and also increases the excretion of AA in the urine and decreases its absorption by about 30%.
With prolonged use, glucocorticosteroids, salicylates, quinoline drugs (including fluoroquinolones), calcium chloride deplete the reserves of ascorbic acid.
Terms and conditions of storage
Keep out of the reach of children at a temperature not exceeding 25 ° C.
The shelf life is 3 years.
Asvitol: prices in online pharmacies
|
Drug name Price Pharmacy |
|
Asvitol 200 mg chewable tablets orange 20 pcs. RUB 20 Buy |
|
Asvitol Solnyshko 25 mg chewable tablets 10 pcs. RUB 20 Buy |
|
Reviews Asvitol Solnyshko-0.025 RUB 20 Buy |
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
