Amoxil
Instructions for use:
- 1. Pharmacological action
- 2. Release form
- 3. Indications for use
- 4. Methods of administration and doses
- 5. Side effects
- 6. Contraindications
Amoxil is an antibiotic belonging to the aminopenicillin group with a broad spectrum of action.
pharmachologic effect
The active ingredient of Amoxil is amoxicillin trihydrate. Amoxicillin is an aminopenicillin of synthetic origin, which has bactericidal properties, but is not sensitive to microorganisms that produce penicillinase, and to some others.
Clavulanic acid is present in Amoxil, which makes it resistant to penicillinase, reduces cross-resistance to antimicrobial drugs.
Release form
Amoxil is produced in tablets of 625, 500, 250 mg, as well as in the form of a powder for infusion of 1.2 g.
Indications for the use of Amoxil
According to the instructions, Amoxil is prescribed for such diseases:
- infections of the gastrointestinal tract and hepatobiliary system;
- kidney and urinary tract infections;
- infections of bone tissue, joints;
- infections of soft tissues and skin.
The use of Amoxil is effective for infectious complications after surgery.
In combination with clarithromycin or metronidazole, Amoxil is used in the treatment of ulcers of the digestive tract, chronic gastritis.
Methods of administration and doses
Following the instructions, Amoxil is administered by infusion and orally.
Infusion (intravenous) administration is carried out in a stream or drip with an interval of 8-12 hours. Amoxil solution is injected immediately after the powder is diluted and is not stored after that.
The average therapeutic dose of Amoxil for adults is 1000/200 mg with an interval of 8 hours. The maximum allowable dose is 100/200 mg with an interval of 6 hours.
During surgical interventions, a single dose of Amoxil 1000 / 200mg is administered before anesthesia, after which in the same volume every six hours.
In the treatment of children, Amoxil is used in the following dosages: up to 3 months. (weighing up to 4 kg) is administered once 25/5 mg per kilogram of weight every 12 hours. From 3 months. up to 12 liters. (weighing more than 4 kg), 25/5 mg is administered per kilogram with an interval of 8 hours.
Taking Amoxil tablets is not associated with food intake, they should be swallowed whole. Amoxil tablets are taken with an interval of 8 hours.
According to the instructions, Amoxil is prescribed for children in the following order: 1-2 years - 30 mg per day per kilogram of weight. From 2 to 5 liters. - 125mg at a time. From 5-10 liters. - 250 mg at a time. From 10 yrs. (with a body weight of more than 40kg) - 250-500mg at a time. The maximum children's dose of Amoxil tablets is 60 mg per kilogram per day.
Adults Amoxil tablets are given 250-500 mg. In severe conditions - 1 g.
Side effects
Amoxil can cause allergic reactions: urticaria, Quincke's edema, erythema, conjunctivitis, rhinitis, less often in the form of eosinophilia, joint pain, fever, anaphylactic shock.
There may also be diarrhea, vomiting, the occurrence of superinfections, nausea while using Amoxil.
When using Amoxil at the same time as metronidazole, anorexia, nausea, constipation, vomiting, diarrhea, pseudomembranous colitis, stomatitis, glossitis, painful sensations in the epigastric region, rarely hepatitis, hematopoietic disorders, interstitial nephritis are possible.
With prolonged use of Amoxil, convulsions, dizziness, depression, loss of consciousness, ataxia, periodic neuropathy were observed.
Contraindications
Amoxil's instructions indicate that the drug cannot be taken if the patient has an increased sensitivity to penicillins, cephalosporins. Also, Amoxil is not used for infectious mononucleosis, during pregnancy, breastfeeding, hematopoietic disorders, lymphocytic leukemia, and diseases of the nervous system.
In addition, in the presence of sensitivity to nitroimidazole derivatives, Amoxil cannot be used simultaneously with metronidazole.
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
