Transulose
Transulose: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Drug interactions
- 11. Analogs
- 12. Terms and conditions of storage
- 13. Terms of dispensing from pharmacies
- 14. Reviews
- 15. Price in pharmacies
Latin name: Transulosa
ATX code: A06AD61
Active ingredient: Lactulose (Lactulosum)
Producer: Laboratoires Chemineau (France)
Description and photo update: 2018-04-07
Transulose is a laxative.
Release form and composition
Dosage form - gel for oral administration: opaque, shiny, dense, fine-grained, from yellow to yellow-orange in color, with a characteristic odor (150 g each in a polypropylene can, one can in a cardboard box complete with a measuring spoon).
Composition of 100 g gel:
- active substances: lactulose - 35 g, liquid paraffin - 42.91 g, soft white paraffin - 21.45 g;
- auxiliary components: aspartame, cholesterol, lactic acid, bixin oil, mandarin oil, lemon oil, orange oil.
Pharmacological properties
Pharmacodynamics
Transulose is a combined drug that has a laxative effect in two ways due to the components that make up it.
Lactulose exhibits an osmotic effect, increasing hydration and the volume of the contents of the colon.
Liquid paraffin and soft white have a mechanical effect, thinning and softening the contents of the colon.
The drug works for 6-8 hours.
Pharmacokinetics
The absorption of lactulose is insignificant and amounts to 0.4–2% in the small intestine. In the colon, it is activated by the saccharolytic flora and is transformed into lactic and acetic acids, which are excreted through the intestines.
Liquid and soft white paraffin is not absorbed.
Indications for use
According to the instructions, Transulose is indicated for the symptomatic treatment of constipation in adults.
Contraindications
Absolute:
- intestinal obstruction (including partial);
- painful abdominal syndrome of unknown origin;
- rectal bleeding (other than those caused by hemorrhoids);
- colostomy;
- ileostomy;
- galactosemia;
- phenylketonuria;
- suspicion of appendicitis;
- acute inflammatory diseases of the abdominal cavity;
- increased sensitivity to drug components;
- age up to 18 years.
Relative contraindications:
- diabetes;
- difficulties in swallowing, including in bedridden patients (risk of bronchial inhalation and fatty pneumopathy).
Instructions for the use of Transulose: method and dosage
The gel is taken orally.
Recommended dosage: at the beginning of therapy - 1 scoop 1-2 times a day. Depending on the result obtained, it is possible to increase the frequency of administration up to 3 times a day. Maintenance daily dose - 1-3 scoops. The maximum dose of Transulose is 3 scoops per day. The duration of therapy is no more than 8 days.
The duration of therapy and the possibility of repeated courses of taking the drug is determined by the attending physician.
Side effects
- digestive system: nausea, flatulence, diarrhea;
- nervous system: headache, dizziness, convulsions;
- other: myalgia, arrhythmia, weakness and increased fatigue.
With prolonged use of the drug, a violation of the water-electrolyte balance, irritation of the perianal region is possible.
Overdose
An overdose symptom is diarrhea, in this case it is recommended to cancel the drug.
special instructions
1 scoop equals 1 teaspoon.
Content of 1 scoop of Transulose: lactulose - 1.75 g, liquid and soft white paraffin - 3.2 g.
When taking the drug, a diet with the use of vegetables containing a large amount of fiber is recommended, as well as physical activity.
Transulose does not contain glucose and can be used in patients with diabetes mellitus.
Long-term use of the drug can reduce the absorption of fat-soluble vitamins (A, D, E, K).
Periodic monitoring of the concentration of electrolytes in serum is required for elderly and debilitated patients taking Transulose for more than 6 months.
Influence on the ability to drive vehicles and complex mechanisms
Due to the possible development of side effects, such as weakness, dizziness and headache, care should be taken when driving vehicles and working with complex mechanisms that require the speed of psychomotor reactions.
Application during pregnancy and lactation
It is not recommended to take the drug during pregnancy and lactation.
Drug interactions
- antibiotics (neomycin), antacids: the effect of Transulose decreases;
- enteric drugs: their pH-dependent release changes;
- diuretics, glucocorticosteroids, amphotericin B: increased potassium loss.
Analogs
There is no information about analogues of Transulose.
Terms and conditions of storage
Store at a temperature not exceeding 30 ° C. Keep out of the reach of children.
Shelf life is 3 years.
Terms of dispensing from pharmacies
Dispensed by prescription.
Reviews about Transulose
There are few reviews about Transulose, noting the effectiveness of the drug, its mild action, ease of use thanks to the supplied measuring spoon, and a pleasant orange scent.
Price for Transulose in pharmacies
The approximate price for Transulose in pharmacies is 380 rubles.
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
