Riabal
Instructions for use:
- 1. Release form and composition
- 2. Indications for use
- 3. Contraindications
- 4. Method of application and dosage
- 5. Side effects
- 6. Special instructions
- 7. Drug interactions
- 8. Analogs
- 9. Terms and conditions of storage
- 10. Terms of dispensing from pharmacies
Riabal is an M-cholinergic blocker, selectively blocking M-cholinergic receptors of the intestinal tract, stomach, urinary and biliary tract, effectively eliminating and preventing spasms of smooth muscles of the ureters, uterus, bile ducts and gallbladder, intestines and esophagus.
Release form and composition
- film-coated tablets: biconvex, rounded, sugar-coated, pink (20 pcs. in blisters, 1 blister in a cardboard box);
- solution for injection: colorless transparent liquid for parenteral administration (2 ml in dark glass ampoules, 6 ampoules in a cardboard box);
- syrup: liquid of sweet caramel taste, orange color (60 ml each in dark glass bottles, complete with a measuring pipette, 1 set in a cardboard box).
1 tablet contains:
- active substance: prifinium bromide - 30 mg;
- auxiliary components: starch, lactose, povidone, magnesium stearate, colloidal silicon dioxide, croscarmellose sodium, gelatin, talc, titanium dioxide, hard paraffin, carnauba wax, sucrose, FD&C red No. 3 dye.
1 ml of solution for injection contains:
- active substance: prifinium bromide - 7.5 mg;
- auxiliary components: sodium chloride, hydrochloric acid, water for injection.
1 ml of syrup contains:
- active substance: prifinium bromide - 1.5 mg;
- auxiliary components: glycerin, propylene glycol, sodium benzoate, sucrose, liquid sorbitol, sodium citrate, sodium saccharin, monoammonium glycyrrhizinate, liquid caramel flavoring, coloring agents: FD&C yellow No. 6 and FD&C red No. 40, purified water.
Indications for use
- pain syndrome associated with increased peristalsis and spasms of the gastrointestinal tract (GIT) caused by acute inflammation of the gastric mucosa, exacerbation of chronic gastritis, gastric and duodenal ulcers, enterocolitis, irritable bowel syndrome;
- pain syndrome associated with spasms of the smooth muscles of the gallbladder and biliary dyskinesia caused by calculous cholecystitis, inflammation of the pancreas, pancreatitis;
- pain syndrome associated with spasm of the urinary tract caused by algomenorrhea, urolithiasis, cystitis (inflammation of the bladder);
- pain syndrome in the epigastric region due to impaired function of the large intestine, accompanied by flatulence and symptoms of intestinal obstruction;
- vomiting, bloating, intestinal colic (spasms of smooth muscles of the gastrointestinal tract) in newborns and infants;
- organic gastrointestinal diseases, vomiting due to acute gastroenteritis, hyperthermia, intracranial hypertension, radiation therapy;
- instrumental and radiological examinations of the gastrointestinal tract (as a means of preliminary preparation before procedures).
Contraindications
- grade III prostatic hypertrophy;
- glaucoma;
- hypersensitivity to prithinium bromide or any component of Riabal.
Method of administration and dosage
Film - coated tablets Riabal tablets are taken orally.
Recommended dosage regimen depending on the patient's age:
- children 6-12 years old - 1 pc. (30 mg) 2-3 times a day;
- children over 12 years old and adults - 1-2 pcs. (30-60 mg) 3 times a day.
If necessary (to relieve sharp acute pain), adults are allowed to take 3 tablets (90 mg) at a time.
Solution for injection
Solution for injection Riabal is administered subcutaneously (s.c.), intravenously (i.v.) or intramuscularly (i.v.), depending on the indication.
Recommended average doses for adults:
- single - 15-30 mg (1-2 ampoules), maximum single - 90 mg (6 ampoules);
- daily - 45-90 mg (3-6 ampoules), maximum daily - 90 mg (6 ampoules);
- exchange rate - 450 mg (30 ampoules), maximum rate - 900 mg (60 ampoules).
For children, Riabal injection solution can be administered from birth at 1 mg / kg of body weight per day (s / c, i / v, i / m).
The duration of therapy is from 7 to 15 days.
The intravenous solution should be injected slowly, over 1 minute, because the rapid introduction of prifinium bromide can provoke a sharp drop in blood pressure and cause the development of a state of shock.
Riabal intravenously is allowed to be used in an isotonic aqueous solution of 0.9% sodium chloride.
Syrup
Riabal syrup is taken orally.
Children over 12 years old and adults are advised to take 20-40 ml of syrup 3 times a day.
Recommended average doses for children over 12 years old and adults:
- single - 15-30 mg, maximum single - 90 mg;
- daily - 45-90 mg, maximum daily - 90 mg;
- exchange rate - 450 mg, maximum exchange rate - 900 mg.
The recommended dosing regimen for children at a frequency of taking 1 time every 6-8 hours:
- up to 3 months - 1 ml each;
- 3-6 months - 1-2 ml each;
- 6-12 months - 2 ml each;
- 1-2 years - 5 ml each;
- 2-6 years old - 5-10 ml each;
- 6-12 years old - 10-20 ml.
The duration of therapy with Riabal syrup is from 7 to 15 days.
Side effects
Due to the use of prifinium bromide, such side effects are rarely noted: violation of accommodation, dry mouth, constipation. They go away on their own after lowering the dose or discontinuing the drug.
special instructions
Taking anticholinergic drugs can cause an increase in intraocular pressure.
In patients with prostatic hypertrophy, the frequency of urination decreases, while the maximum bladder volume increases, which leads to a worsening of dysuria.
There are no contraindications for taking prifinium bromide during pregnancy and lactation.
Drug interactions
Prifinium bromide enhances the effect of antidepressants, narcotic analgesics, antipsychotic and antihistamines (neuroleptics), M-anticholinergic and antiparkinsonian drugs, and therefore the risk of potentiation of their side effects increases.
Analogs
Riabal's analogs are: Bebinos, Bromocriptine, Ganaton, Bimaral, Gaviscon, Digestal, Galidor, Domperidon, Gastenorm forte, Itomed, Carbopect, Gestid, Markalact, Disflatil, Mezim forte, Iberogul, Magoksia, Mietovit, Yogumoni Metamol, No-shpa forte, Metoclopramide, Panzinorm Forte, Motilak, Penzital, Pancreatin, Rennie, Perinorm, Simikol, Sab simplex, Spazmonet, Smecta, Festal, Trimedat, Holenzym, Hilak forte, Zeolate, Hofziman, Espeniuenmi spasm.
Terms and conditions of storage
Store at 15-25 ° C, tablets - in a dry place, syrup - out of direct sunlight. Keep out of the reach of children.
Shelf life: solution and syrup - 3 years, tablets - 5 years.
Terms of dispensing from pharmacies
Dispensed by prescription.
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
