Nasobek
Instructions for use:
- 1. Release form and composition
- 2. Indications for use
- 3. Contraindications
- 4. Method of application and dosage
- 5. Side effects
- 6. Special instructions
- 7. Drug interactions
- 8. Analogs
- 9. Terms and conditions of storage
- 10. Terms of dispensing from pharmacies
Prices in online pharmacies:
from 159 rub.
Buy
Nasobek is a glucocorticosteroid (GCS) with anti-inflammatory, antiallergic and immunosuppressive effects for intranasal use.
Release form and composition
Dosage form - dosed nasal spray: an opaque suspension without visible foreign inclusions, white (200 doses in plastic bottles equipped with a mechanical dosing applicator, 1 bottle in cardboard boxes).
Active substance: beclomethasone dipropionate, in 1 spray dose - 50 mcg.
Additional components: microcrystalline cellulose + sodium carmellose (dispersive cellulose), phenylethanol, hydrochloric acid 35%, polysorbate 80, anhydrous dextrose, benzalkonium chloride (50% solution), purified water.
Indications for use
- Allergic rhinitis (seasonal and year-round);
- Vasomotor rhinitis.
Contraindications
Absolute:
- Frequent nosebleeds;
- Viral infectious diseases;
- Fungal infections;
- Respiratory tuberculosis;
- Hemorrhagic diathesis;
- I trimester of pregnancy;
- Children under 6 years old;
- Hypersensitivity to drug components.
Relative:
- Ulceration of the nasal septum;
- Recently undergone surgery in the nasal cavity, nasal trauma;
- Glaucoma;
- Amoebiasis;
- Severe liver failure;
- Hypothyroidism;
- Recently suffered myocardial infarction;
- II and III trimesters of pregnancy;
- Lactation.
Method of administration and dosage
Nasobek is intended for intranasal use.
Recommended doses:
- Adults and adolescents over 12 years of age: 1-2 doses (50-100 mcg beclomethasone) in each nasal passage 2 times a day;
- Children 6-12 years old: 1 dose in each nostril 2 times a day. If necessary, it is possible to use 2 doses 2 times a day.
The maximum daily dose is 400 mcg, it can be divided into 2-4 applications.
After achieving a therapeutic effect, the dose should be gradually reduced, up to the complete withdrawal of the drug.
Rules for using Nasobek:
- Before the first use, remove the protective plastic half-ring located between the dispensing applicator and the screw-on part;
- Clear the nasal passages;
- Shake the bottle, then remove the cap;
- Place the bottle in the palm of your hand so that its bottom rests on the thumb, and the middle and index fingers rest on both opposite sides of the lower part of the nasal applicator;
- Press the dispenser several times until a cloud of aerosol appears (this procedure must be performed before the first use and repeated in cases of a long break in using the drug);
- Breathe out lightly through the nose;
- Pinch the nasal passage with your finger, into which the drug will not be injected;
- Insert the applicator into the free nostril;
- Tilt your head slightly so that the bottle is in a perpendicular position;
- Introduce a dose of aerosol by pressing the applicator while inhaling slightly with an open nasal passage;
- Exhale through your mouth;
- If necessary, enter a second dose as described;
- Repeat the same procedure with the second nostril;
- Clean the upper (end) part of the applicator with a clean cloth and close with a cap.
The nasal applicator should be cleaned at least once a week to prevent clogging: gently press the lower part of the applicator and disconnect it, rinse the applicator and the cap with warm water, let them dry, then put them back on the bottle.
Side effects
Nasobeks are generally well tolerated. Rarely (including isolated cases), the following side effects occur:
- Allergic reactions: urticaria, skin rash, angioedema;
- From the side of the organ of vision: decreased vision, conjunctival hyperemia; with prolonged use - increased intraocular pressure, including cataracts, glaucoma;
- From the nervous system: disturbance of taste and smell, headache, drowsiness, dizziness;
- From the respiratory system: sneezing, nasal congestion, burning, irritation and dryness of the nasopharynx, rhinorrhea, atrophy of the nasal mucosa, nosebleeds, ulceration of the nasal mucosa, cough, perforation of the nasal septum (more often in patients who have undergone previous surgical intervention in the nasal cavity);
- Others: myalgia; with prolonged and / or use in high doses (more than 400 μg / day) - candidiasis of the oral cavity and upper respiratory tract, adrenal insufficiency, decreased bone mineral density, decreased growth rate in children.
special instructions
Care should be taken when using the drug and avoid contact with the eyes.
Unlike local vasoconstrictor agents, the therapeutic effect of Nasobek is not immediately apparent. Improvement of the condition is usually noted after 5-7 days from the start of treatment. After achieving the effect, the dose of the drug must be reduced to the minimum effective, which will control the course of the disease.
Patients at risk of developing adrenal cortex insufficiency should be under constant monitoring during treatment.
Infectious diseases of the nasal cavity and paranasal sinuses are not a contraindication to the use of Nasobek, but they require appropriate therapy.
The drug slows down the healing of wounds, therefore, patients with ulceration of the nasal septum, patients after nasal trauma or surgery in the nasal cavity should not use Nasobek until the wounds have healed completely.
Benzalkonium chloride, which is part of the drug as a preservative, increases the likelihood of developing edema of the nasal mucosa with prolonged use. If such a reaction occurs, it is necessary to adjust the dose of Nasobek or to prescribe another drug that does not contain benzalkonium chloride.
With prolonged use of this drug in pediatrics, the growth dynamics of children should be monitored.
In some cases, Nasobek causes drowsiness and dizziness, therefore it is recommended to be careful when driving a car and performing tasks that require increased attention and high reaction speed.
Drug interactions
Nasobek enhances the effect of beta-adrenergic agonists.
With the simultaneous use of inducers of enzymes of microsomal oxidation (rifampicin, phenytoin, phenobarbital) reduce the effectiveness of beclomethasone.
Oral glucocorticosteroids, beta 2 -adrenomimetics, estrogens and methandrostenolone, when used together, enhance the effect of beclomethasone.
Analogs
Nasobek's analogs are: Beklospir, Beklazon-Eco, Klenil, Bekotid, Beklat, Beclomethasone Orion Pharma, Rinoklenil, Aldecin, Beclorin.
Terms and conditions of storage
Store at temperatures up to 25 ºС in a place out of the reach of children, protected from light.
Shelf life - 4 years, after the first opening of the bottle - 6 months.
Terms of dispensing from pharmacies
Dispensed by prescription.
Nasobek: prices in online pharmacies
|
Drug name Price Pharmacy |
|
Nasobek 50 mcg / dose 200 doses nasal spray dosed 1 pc. 159 r Buy |
|
Nasobek nasal spray. dosage. 50mcg / dose 200 doses RUB 185 Buy |
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
