Nazivin sensitive
Nazivin sensitive: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. In case of impaired renal function
- 12. Drug interactions
- 13. Analogs
- 14. Terms and conditions of storage
- 15. Terms of dispensing from pharmacies
- 16. Reviews
- 17. Price in pharmacies
Latin name: Nasivin Sensitive
ATX code: R01AA05
Active ingredient: oxymetazoline (oxymetazoline)
Manufacturer: Pharmaster (France), Ursapharm Arzneimittel GmbH (Germany), Merck Selbstmedikation GmbH (Merck Selbstmedikation GmbH) (Germany)
Description and photo updated: 22.11.2018
Prices in pharmacies: from 158 rubles.
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Nazivin sensitive is a vasoconstrictor drug for topical use in otolaryngology.
Release form and composition
Dosage form of Nazivin sensitive:
- nasal drops 0.01%: clear or almost transparent liquid from yellowish to colorless (5 ml in vials, 1 vial in a cardboard box);
- dosed nasal spray: clear or almost transparent liquid from yellowish to colorless (10 ml in vials, 1 vial in a cardboard box).
Composition of 1 ml drops:
- active substance: oxymetazoline hydrochloride - 100 μg;
- auxiliary components: citric acid monohydrate, sodium citrate dihydrate, glycerol 85%, purified water.
Composition of 1 ml dosed nasal spray:
- active substance: oxymetazoline hydrochloride - 250 or 500 mcg;
- auxiliary components: citric acid monohydrate, sodium citrate dihydrate, glycerol 85%, purified water.
Pharmacological properties
Pharmacodynamics
When applied topically, Nazivin reduces nasal discharge and swelling of the nasal mucosa, facilitating nasal breathing. Reduces the likelihood of bacterial complications such as sinusitis, sinusitis, otitis media by restoring aeration of the nasal cavity, and its paranasal sinuses, as well as the middle ear cavity. When used according to the recommendations, oxymetazoline does not irritate and does not lead to hyperemia of the nasal mucosa, and also does not have a systemic effect. The effect of the drug occurs within a few minutes after its application, and lasts up to 12 hours.
Pharmacokinetics
The half-life of the drug when applied topically is 35 hours. 2.1% is excreted in the urine, 1.1% of the dose in the feces.
Indications for use
- colds and acute respiratory viral diseases (ARVI) of the upper respiratory tract, accompanied by rhinitis; vasomotor rhinitis in the acute stage; acute allergic rhinitis - to facilitate nasal breathing;
- eustachitis, sinusitis, otitis media - to facilitate the outflow of discharge from the paranasal sinuses;
- diagnostics of the sinuses - to eliminate edema before manipulations.
Contraindications
Absolute contraindications:
- angle-closure glaucoma;
- atrophic rhinitis;
- age up to 1 year (for a spray 11.25 mcg / dose), up to 6 years (for a spray 22.5 mcg / dose);
- increased sensitivity to the components of the drug.
Relative contraindications:
- increased intraocular pressure;
- chronic heart failure;
- arterial hypertension;
- angina pectoris;
- arrhythmia;
- chronic renal failure;
- hyperplasia of the prostate with urinary retention;
- severe atherosclerosis;
- hyperthyroidism;
- diabetes;
- pheochromocytoma;
- therapy with monoamine oxidase (MAO) inhibitors within the previous 2 weeks, as well as within 2 weeks after their cancellation;
- taking tricyclic antidepressants, bromocriptine.
Instructions for use of Nazivin sensitive: method and dosage
Nazivin sensitive is used intranasally in each nasal passage.
Use Nazivin Sensitive without a doctor's prescription for no longer than 5-7 days. When the condition does not improve or symptoms worsen within 3 days of using the drug, it is advisable to consult a doctor. A repeated course of therapy is possible only after a few days.
Exceeding the dose of the drug is not allowed without the recommendation of a medical specialist.
Nasal drops
In the form of drops, Nazivin sensitive is used for children under the age of 1 year.
Recommended dosage:
- children under 4 weeks: 1 drop 2-3 times a day;
- children from 5 weeks of age: 1-2 drops 2-3 times a day.
It is also allowed to treat the nasal cavity with cotton turundas soaked in solution.
The drug is instilled with the child's head thrown back. It is recommended to turn the bottle over before use.
Dosed nasal spray
Recommended dosage:
- children 1-6 years old: 1 spray of 11.25 mcg / dose 2-3 times a day;
- children over 6 years old and adults: 1 injection of spray 22.5 mcg / dose 2-3 times a day.
Side effects
- local reactions: dryness and burning of the mucous membrane of the nasal cavity, sneezing, severe nasal congestion that occurs after the effect of the drug has passed, visual impairment (if it gets into the eyes). With prolonged therapy, tachyphylaxis, atrophy of the nasal mucosa, medication rhinitis are possible;
- cardiovascular system: increased blood pressure (BP), tachycardia, palpitations;
- nervous system: insomnia, headache, dizziness, irritability, anxiety, sleep disturbance (in children);
- other: nausea, exanthema.
Overdose
Overdose symptoms of Nazivin sensitive: nausea, increased blood pressure, depression of the central nervous system (CNS), tachycardia.
Symptomatic therapy is recommended.
special instructions
Avoid contact of Nazivin with eyes.
To prevent the spread of infection, the drug must be used individually.
Influence on the ability to drive vehicles and complex mechanisms
Long-term use of oxymetazoline can cause undesirable reactions from the cardiovascular system and the central nervous system. In this case, care should be taken when driving vehicles and other complex mechanisms that require the speed of psychomotor reactions.
Application during pregnancy and lactation
The use of the drug during pregnancy and lactation is possible only in the recommended dose, and in the case when the expected benefit to the mother outweighs the possible risk to the fetus or child.
Pediatric use
Nazivin Sensitive for children under 1 year of age is intended in the form of drops, for children 1-6 years old - nasal spray dosed at 11.25 mcg / dose, for children over 6 years old - nasal spray dosed at 22.5 mcg / dose.
With impaired renal function
According to the instructions, Nazivin sensitive should be used with caution in patients with renal insufficiency.
Drug interactions
- local anesthetic drugs: their absorption slows down and the duration of action is lengthened;
- vasoconstrictor drugs: the risk of unwanted effects increases;
- tricyclic antidepressants, MAO inhibitors (including within 2 weeks after their cancellation and 2 weeks before their appointment), other drugs that increase blood pressure: the risk of a pronounced increase in blood pressure.
Analogs
The analogues of Nazivin Sensitive are Afrin, Vicks Active Sinex, Nazol, Nazol Advance, Nazo-spray, Nesopin, Noxprey, Oxymetazolin, Oxyphrin, Otrivin, Rinostop, Sialor Rino.
Terms and conditions of storage
Store at a temperature not exceeding 30 ° C. Keep out of the reach of children.
Shelf life is 3 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Nazivin sensitive
Reviews about Nazivin sensitive online are quite diverse. Most patients note a rapid vasoconstrictor effect of the drug, which persists for a long time. At the same time, there are reports that drops and spray do not help to facilitate breathing in both infants and adults.
Among the disadvantages are the possibility of developing addiction and a small volume of the drug in the form of drops.
The price of Nazivin sensitive in pharmacies
The approximate price for Nazivin sensitive, nasal drops 0.01%, 5 ml in a bottle is 220 rubles; dosed nasal spray (11.25 μg / dose) 10 ml in a bottle - 190 rubles, nasal dosed spray (22.5 μg / dose) 10 ml in a bottle - 200 rubles.
Nazivin sensitive: prices in online pharmacies
|
Drug name Price Pharmacy |
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Nazivin Sensitiv 11.25 mcg / dose nasal spray dosed for children from 1 year to 6 years 10 ml 1 pc. 158 RUB Buy |
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Nazivin Sensitiv nasal spray. dosage. 22.5mkg / dose 10ml 162 RUB Buy |
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Nazivin Sensitiv nasal spray. dosage. 11.25mkg / dose 10ml 162 RUB Buy |
|
Nazivin Sensitiv 22.5 mcg / dose nasal spray dosed for adults and children over 6 years old 10 ml 1 pc. 162 RUB Buy |
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
