Intesty bacteriophage
Intesty-bacteriophage: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. Drug interactions
- 12. Analogs
- 13. Terms and conditions of storage
- 14. Terms of dispensing from pharmacies
- 15. Reviews
- 16. Price in pharmacies
Latin name: Bacteriophagum intestinalis fluidum
ATX code: V03A
Active ingredient: Sterile filtrates of phagolysates of Shigella, Salmonella, etiologically significant serotypes of enteropathogenic Escherichia coli, Proteus vulgaris and Proteus mirabilis, staphylococci, enterococci, Pseudomonas aeruginosa pseudomonads
Manufacturer: Microgen NPO FGUP MZ RF (Russia)
Description and photo update: 18.10.2018
Prices in pharmacies: from 448 rubles.
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Intesty-bacteriophage is a viral agent that invades bacterial cells and causes their lysis; immunobiological preparation.
Release form and composition
Dosage form - solution for oral administration or rectal administration: transparent liquid from light yellow to yellow, greenish tint is allowed (in vials: 20 ml each, 4 or 10 vials in a cardboard box; 100 ml each, 1 vial in a cardboard box) …
Intesti-bacteriophage contains:
- active ingredients: a mixture of sterile filtrates of Shigella flexneri phagolysates 1, 2, 3, 4, 6 serovars, Salmonella paratyphi A, Shigella sonnei, Salmonella paratyphi B, Salmonella infantis, Salmonella typhimurium, Salmonella choleraesuis, Salmonella enteritidis, Protemonella mi oranus vulgaris, Enterococcus, Pseudomonas aeruginosa, Staphylococcus, various serogroups (the most significant in the etiology of enteral diseases) enteropathogenic Escherichia coli;
- auxiliary component: quinosol.
Pharmacological properties
Pharmacodynamics
The biological property of the drug is the ability to cause specific lysis of bacteria Shigella sonnei, Shigella flexneri 1, 2, 3, 4, 6 serovariants, Salmonella paratyphi A, Salmonella typhimurium, Salmonella paratyphi B, Salmonella choleraesuis, Salmonella infantis, Salmonella enteritidis, Salmonella orania, Proteus mirabilis, Proteus vulgaris, Enterococcus, Pseudomonas aeruginosa, Staphylococcus.
Indications for use
The use of Intesti-bacteriophage is indicated for the prevention and treatment of the following gastrointestinal pathologies caused by the following bacteria Salmonella spp., Dysentery, Escherichia coli, Enterococcus spp., Proteus spp., Pseudomonas aeruginosa, Staphylococcus spp. or their combination:
- dysbiosis;
- bacterial dysentery;
- dyspepsia;
- salmonellosis;
- colitis, enterocolitis.
Contraindications
Intesti-bacteriophage should not be used in case of individual intolerance to the drug components.
Instructions for use of Intesti-bacteriophage: method and dosage
The solution is taken orally or injected rectally from the first day of the disease.
The dose of the drug is prescribed by the doctor, taking into account clinical indications. The use of the drug should be started after preliminary determination of the phage sensitivity of the pathogen.
The recommended treatment regimen for adults: inside - 4 times a day, 0.5-1 hour before meals; the duration of treatment is 7-10 days.
Treatment of children in the first months of life should be started with the drug diluted in boiled water in a ratio of 1 to 2. If the child does not develop unwanted reactions in the form of regurgitation and skin rashes after 2 days of therapy, then the bacteriophage can be used undiluted.
With indomitable vomiting, the child is prescribed daily administration of the drug through high enemas (using a gas tube or catheter). If necessary, you can combine rectal (in the form of high enemas) and oral administration of the drug. When treating children, the frequency of oral administration is 3 times a day, 0.5 hours before meals.
Recommended single dose for children, depending on age:
- 0–0.5 years: inside - 5 ml, rectally - 10 ml;
- 0.5–1 years: inside - 10–15 ml, rectally - 20 ml;
- 1-3 years: inside - 15-20 ml, rectally - 20-30 ml;
- 3–8 years: inside - 20–30 ml, rectally - 30–40 ml;
- 8 years and older: inside - 30-40 ml, rectally - 50-60 ml.
Children without colitis are advised to replace one oral dose with a single dose of an age-specific dose in the form of an enema, after a preliminary bowel movement.
For the purpose of prevention, it is necessary to take a single age dose of the drug daily, the duration of admission is determined in accordance with the conditions of the epidemiological situation.
Side effects
In infants, after the first two days of taking the drug inside, undesirable phenomena in the form of regurgitation and rash on the skin may appear.
Overdose
Overdose symptoms were not found.
special instructions
You can not use a cloudy drug - this indicates the presence of bacteria from the environment in it.
Since the drug contains a nutrient medium for the development of bacteria, strict adherence to the rules of asepsis is required when opening the bottle. After thoroughly washing your hands, treat with an alcohol-containing solution and remove the cap without opening the plugs. Do not allow the inner surface of the cork to come into contact with any objects. With repeated use of the contents of the vial (in the case of the appointment of small doses), it is recommended to take the solution with a sterile syringe and close it tightly with a stopper.
After opening, the bottle is stored only in the refrigerator, the bacteriophage can be used throughout the shelf life in the absence of turbidity.
Application during pregnancy and lactation
The use of the drug during pregnancy and breastfeeding is possible only on the recommendation of a doctor and after laboratory confirmation of the presence of infections sensitive to the bacteriophage.
Pediatric use
According to the instructions, Intesti-bacteriophage can be used in children from the first days of life as prescribed by a doctor.
Drug interactions
Shows the simultaneous use of antibiotics and other drugs.
Analogs
Analogs of Intesti-bacteriophage are: Ersefuril, Sextafag, Bacteriophage Klebsiella polyvalent purified, Bacteriophage coli, Bacteriophages staphylococcal typical diagnostic dry - England (international set), etc.
Terms and conditions of storage
Store in a dark place at a temperature of 2-8 ° C, including during transportation. Keep out of the reach of children.
For transportation of the drug for no more than 1 month, a storage temperature of 8–25 ° C is allowed.
The shelf life is 24 months.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews of Intesti-bacteriophage
Reviews of Intesti-bacteriophage are mostly positive.
Price for Intesty-bacteriophage in pharmacies
The price of Intesti-bacteriophage for a 100 ml bottle is 800-900 rubles, packing (4 20 ml bottles) - about 650 rubles.
Intesty-bacteriophage: prices in online pharmacies
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Drug name Price Pharmacy |
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Intesti-bacteriophage solution for oral administration or for rectal administration 20 ml 4 pcs. 448 r Buy |
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Intesti-bacteriophage solution for oral administration or for rectal administration 100 ml 1 pc. 534 RUB Buy |
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
