Dioxisol
Dioxizol: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. In case of impaired renal function
- 11. Drug interactions
- 12. Analogs
- 13. Terms and conditions of storage
- 14. Terms of dispensing from pharmacies
- 15. Reviews
- 16. Price in pharmacies
Latin name: Dioxysol
ATX code: D08A
Active ingredient: Hydroxymethylquinoxalindioxide + Trimecaine (Hydroxymethylquinoxalindioxide + Trimecaine)
Manufacturer: Moskhimfarmpreparaty them. N. A. Semashko (Russia); Darnitsa, FF, PrJSC (Ukraine)
Description and photo update: 18.10.2018
Dioxizol is a combined antimicrobial agent (local anesthetic + antimicrobial).
Release form and composition
Aerosol for external and local use: a liquid that forms a white foam when leaving the container (30 or 60 g in aluminum aerosol cans with a nozzle, 1 can in a cardboard box).
Aerosol composition (in 1 bottle):
- active ingredients: dioxidine - 300/600 mg, trimecaine - 1500/3000 mg;
- excipients: proxanol, propylene glycol, freon, purified water.
Pharmacological properties
Pharmacodynamics
Dioxisol stimulates regeneration processes, has a local anesthetic, antibacterial and anti-burn effect. Eliminates perifocal and wound inflammation, activates the reparation processes and the action of phagocytes in the wound.
The antibacterial function is due to the presence of dioxidine and includes an effect on gram-positive and gram-negative, anaerobic and aerobic, asporogenic and spore-forming microflora, hospital strains of bacteria with multi-resistance to other chemotherapeutic drugs.
When applied topically, the drug does not damage grafts and granulation tissue. Does not have a local irritating and general toxic effect.
Indications for use
- infected wounds of soft tissues, fistulas, trophic ulcers, abscesses, bedsores;
- 2nd-4th degree burns (deep and superficial);
- prevention of purulent-inflammatory processes in cosmetology and military field surgery, when performing plastic surgery;
- Phase I of the wound process and phase II with the growth of granulation tissue in the wound with persistent zones of inflammation and necrosis.
It is used in traumatology, surgery, proctology.
Contraindications
The drug is contraindicated in case of high sensitivity to its components.
Instructions for use of Dioxisol: method and dosage
According to the instructions, Dioxizol is intended for local or external use.
It is used after pretreatment of the wound with the removal of necrotic tissue and exudate. The aerosol is applied to the affected area, completely covering the wound with foam. The required amount of the drug for a single use depends on the area of the wound surface.
In the treatment of burns, the foam is applied in a uniform layer 1 cm thick and a gauze bandage is applied. Dressings must be changed once a day. Using a nozzle, foam is injected into fistulas, wound cavities and pockets 1-2 times a day. Before each use, rinse the nozzle with boiled water.
The daily dose for external use is 100 g, with the introduction into the cavity - 70 g.
The duration of treatment depends on the course of the wound process and should not exceed 15 days.
Side effects
- burning;
- itching;
- allergic reactions.
Overdose
There is no data on overdose.
special instructions
There is no data.
Application during pregnancy and lactation
During pregnancy and lactation, Dioxizol should be used with caution.
With impaired renal function
In case of impaired renal and adrenal function, it is recommended to take the drug with caution.
Drug interactions
No exposure with other medicinal products was noted.
Analogs
Dioxisol's analogs are Dioxidin and Hyposol.
Terms and conditions of storage
Store at temperatures between 0 and 30 ° C. Keep away from light and children.
Shelf life - 2 years 6 months.
Terms of dispensing from pharmacies
Dispensed by prescription.
Reviews about Dioxizole
Reviews of Dioxizole are in most cases positive. Those taking the drug note that the effectiveness of the treatment is noticeable in a short period of time.
Price for Dioxizol in pharmacies
The price of Dioxizol is unknown due to the lack of the drug in the Russian pharmacy chain. The cost of Dioxidin ointment with a similar active ingredient is approximately 400 rubles.
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
