Groprinosin - Instructions For Use, Reviews, Indications

2024 Author: Rachel Wainwright | [email protected]. Last modified: 2023-12-15 07:39

Groprinosin

Instructions for use:

1. 1. Pharmacological action
2. 2. Release form
3. 3. Analogs
4. 4. Indications for use
5. 5. Contraindications
6. 6. Method of application
7. 7. Drug interactions
8. 8. Side effects
9. 9. Storage conditions

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from 276 rubles.

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Groprinosin, the active ingredient inosine pranobex (inosine pranobex) is an antiviral, immunostimulating drug.

Groprinosin is recommended for use in patients with insufficient natural immune defense.

Pharmacological action Groprinosin

Groprinosin has an antiviral and immunostimulating effect on the body due to the combination of inosine and 4-acetamidobenzoic acid salt with N, N-dimethylamino-2-propanol, molar ratio 1: 3.

The inosine present in the preparation determines the effectiveness of the complex, and the availability for lymphocytes increases the second component in Groprinosin. Stimulating biochemical processes in macrophages, the drug helps to increase the production of interleukins, enhance the production of antibodies, and stimulates the formation of cytokines due to the proliferation of lymphocytes.

The use of Groprinosin helps to reduce the clinical manifestations of viral diseases, accelerate convalescence, and increase the body's resistance.

As an adjunct drug in the case of infectious lesions of the skin and mucous membranes with the Herpes simplex virus, Groprinosin promotes faster healing of the affected surfaces. The appearance of new bubbles, edema, erosion, relapse of the disease decreases.

Due to its low toxicity, Groprinosin is well tolerated by elderly patients, as well as by patients with chronic circulatory failure and angina pectoris.

Timely use of Groprinosin reduces the frequency of viral infection and reduces the severity and duration of diseases.

Form of release Groprinosin

Groprinosin - white tablets, biconvex. On one side of the risk for division. The surface of the tablets is uniform, smooth, without damage and stains.

One tablet of Groprinosin contains the main active ingredient - inosine pranobex (500 mg), excipients: potato starch (85 mg), polyvinylpyrrolidone K25 (45 mg), magnesium stearate (10 mg).

Pack of 10 in blisters, cardboard packs of 2 and 5 blisters.

Analogs Groprinosin

The analogue of Groprinosin in terms of the active ingredient is Isoprinosin tablets.

Groprinosin's analogs, similar in the mechanism of action and belonging to the same pharmacological subgroup:

• Tablets - Alpizarin, Amiksin, Arbidol, Amizon, Virasept, Hyporamine, Isentress, Yodantipirin, Kagocel, Lavomax, Nikavir, Ergoferon, Polyferon-CD4, Celsentri, Tilaxin, Tiloron;
• Capsules - Arbidol, Ingavirin, Tiloron, ORVitol NP;
• Vaginal suppositories - Hyporamine, Panavir;
• Rectal suppositories - Hyporamine, Panavir;
• Powder for oral administration - Viracept, Lirasept;
• Nasal ointment - Oxolin;
• Gel for local and external use - Panavir;
• Preparations for the preparation of solutions for injections, infusions, inhalations - Allokin-alpha lyophilisate, Armenicum, Hyporamine, Panavir, Fuzeon;
• Liquid extract for local and oral administration - Proteflazid;
• Solution for intramuscular injection - Ferrovir.

Indications for use of Groprinosin

According to the instructions, Groprinosin is recommended for administration in case of immunodeficiency states of the body caused by viral infections with normal or weakened immunity.

Groprinosin, according to the instructions, is prescribed in the case of:

• Diseases caused by Herpes simplex type I and II viruses of various localization;
• Cytomegalovirus;
• Subacute sclerosing panencephalitis.

Contraindications

According to the instructions, Groprinosin is not used for:

• Gout;
• Urolithiasis;
• Chronic renal failure;
• Arrhythmias;
• Pregnancy;
• During lactation;
• Hypersensitivity to drug components.

Groprinosin is not assigned to children under 3 years of age or weighing less than 15-20 kg.

The drug must be prescribed with caution when taken simultaneously with diuretics, zidovudine, xanthine oxidase inhibitors, as well as in case of acute renal failure.

Method of application Groprinosin

Method of application Groprinosin, according to the instructions - inside after eating 3-4 times a day at regular intervals of 6 or 8 hours, drinking a little water.

Adults - 3-4 grams (6-8 tablets) per day, children - at the rate of 50 mg of the drug per 1 kg of the child's weight per day.

When using Groprinosin in children and adults in the case of severe infectious diseases, it is allowed to increase the dose of the drug to 100 mg / kg of body weight per day, but only individually and under the supervision of the attending physician.

Groprinosin is usually used for 5 days; in case of complications during the course of the disease, the reception can be extended. The course of treatment is repeated if necessary after a break of 8 days.

As an immunostimulant, the drug is prescribed for administration for 3-9 weeks, daily or 3 times a week, at a dose of 50 mg / kg of the patient's weight per day.

Drug interaction Groprinosin

With the simultaneous use of Groprinosin with immunosuppressants, the immunostimulating effectiveness of the drug is weakened.

Groprinosin, according to the instructions, should be taken with caution when taken simultaneously with:

• Xanthine oxidase inhibitors (allopurinol), loop diuretics (torasemide, furosemide, ethacrynic acid). They increase the concentration of uric acid in the blood serum;
• Zidovudine. Groprinosin increases the plasma concentration of zidovudine and its half-life.

Side effects of Groprinosin

The use of Groprinosin, according to reviews, causes adverse reactions mainly at the beginning of treatment.

The most common side effects of the use of Groprinosin, according to reviews, are decreased appetite, vomiting, nausea, diarrhea. Other reactions are minor allergies, an insignificant increase in the concentration of uric acid in the blood and urine.

Studies of the effect of the use of Groprinosin on psychomotor have not been carried out, therefore, one should be careful when driving vehicles and other mechanisms while taking the drug, since the use of Groprinosin, according to reviews, can cause drowsiness and dizziness.

Storage conditions

Keep out of reach of children, protected from light, dry place. The temperature is not higher than 25 ° C. Expiration date - 3 years from the date of manufacture.

Groprinosin: prices in online pharmacies

Drug name Price Pharmacy

Groprinosin 50 mg / ml syrup 150 ml 1 pc. 276 r Buy

Groprinosin - Richter syrup 50 mg / ml bottle 150 ml 451 RUB Buy

Groprinosin 500 mg tablets 20 pcs. RUB 536 Buy

Groprinosin tablets 500mg 20 pcs. 546 r Buy

Groprinosin 500 mg tablets 30 pcs. 687 r Buy

Groprinosin tablets 500mg 30 pcs. 727 RUB Buy

Groprinosin 500 mg tablets 50 pcs. 1169 RUB Buy

Groprinosin tablets 500mg 50 pcs. 1407 RUB Buy

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Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!