Viferon - Instructions For Use, Indications, Doses, Analogues

2024 Author: Rachel Wainwright | [email protected]. Last modified: 2023-12-15 07:39

Viferon

Instructions for use:

1. 1. Release form and composition
2. 2. Indications for use
3. 3. Contraindications
4. 4. Method of application and dosage
5. 5. Side effects
6. 6. Special instructions
7. 7. Drug interactions
8. 8. Analogs
9. 9. Terms and conditions of storage
10. 10. Terms of dispensing from pharmacies

Prices in online pharmacies:

from 113 rub.

Buy

Viferon is an immunomodulatory, antiproliferative and antiviral drug.

Release form and composition

Viferon is released in the form:

• Ointment for local and external use - homogeneous, viscous, yellowish-white or yellow color, with a specific lanolin smell (6 g or 12 g in aluminum tubes, 12 g in polystyrene cans, 1 tube or can in a cardboard box);
• Gel for local and external use - gel-like, opaque, homogeneous white mass with a grayish tint (12 g in aluminum tubes or in polystyrene cans, 1 tube or can in a cardboard box);
• Suppositories for rectal use - bullet-shaped, uniform consistency, white with a yellowish tinge, with a diameter of up to 10 mm (10 pcs. In blisters, 1 or 2 packs in a cardboard box).

The composition of 1 g of ointment includes:

• Active substance: human recombinant interferon alpha-2b - 40,000 International units (IU);
• Auxiliary components: anhydrous lanolin - 0.34 g; tocopherol acetate - 0.02 g; peach oil - 0.12 g; medical petroleum jelly - 0.45 g; purified water - up to 1 g.

The composition of 1 g of gel includes:

• Active substance: human recombinant interferon alpha-2b - 36,000 IU;
• Auxiliary components: 95% ethanol - 0.055 g; alpha-tocopherol acetate - 0.055 g; methionine - 0.0012 g; benzoic acid - 0.00128 mg; citric acid monohydrate - 0.001 g; sodium chloride - 0.004 g; sodium tetraborate decahydrate - 0.0018 mg; distilled glycerin (glycerol) - 0.02 g; 10% solution of human serum albumin - 0.02 g; carmellose sodium - 0.02 g; purified water - up to 1 g.

1 suppository contains:

• Active substance: human recombinant interferon alpha-2b - 150,000, 500,000, 1,000,000 or 3,000,000 IU;
• Auxiliary components: ascorbic acid - 0.0054 / 0.0081 / 0.0081 / 0.0081 g, respectively; alpha-tocopherol acetate - 0.055 g each; disodium edetate dihydrate - 0.0001 g each; sodium ascorbate - 0.0108 / 0.0162 / 0.0162 / 0.0162 g, respectively; polysorbate 80 - 0.0001 g each;
• Base: confectionery fat and cocoa butter - up to 1 g.

Indications for use

Viferon in the form of an ointment is prescribed for the treatment of the following diseases:

• Acute respiratory viral infections (ARVI) and influenza in children over 1 year old;
• Viral (including herpetic) lesions of the mucous membranes and skin of various localization.

The preparation in the form of a gel is indicated for use:

• ARVI, including influenza, long-term and frequent ARVI, incl. proceeding with complications of bacterial infections (prevention, simultaneously with other drugs);
• Recurrent stenosing laryngotracheobronchitis (prevention, along with other drugs);
• Herpetic cervicitis (along with other drugs);
• Herpetic infection of mucous membranes and skin (acute and exacerbations of chronic recurrent), incl. urogenital form of herpes infection (simultaneously with other drugs).

Viferon in the form of suppositories is used simultaneously with other drugs in the treatment of diseases:

• SARS, including influenza, incl. proceeding with complications of bacterial infections, pneumonia (chlamydial, viral, bacterial) in adults and children;
• Chronic viral hepatitis B, C, D in adults and children, incl. in combination with the use of hemosorption and plasmapheresis in chronic viral hepatitis of pronounced activity, which are complicated by liver cirrhosis;
• Infectious and inflammatory diseases in newborns (including premature babies): sepsis, meningitis (viral, bacterial), intrauterine infection (enterovirus infection, chlamydia, CMV infection, herpes, mycoplasmosis, candidiasis, including visceral);
• Recurrent or primary herpes infection of the mucous membranes and skin, localized form, moderate and mild course, including the urogenital form in adults;
• Infectious and inflammatory diseases of the urogenital tract (bacterial vaginosis, ureaplasmosis, chlamydia, papillomavirus infection, CMV infection, gardnerellosis, trichomoniasis, mycoplasmosis, recurrent vaginal candidiasis) in adults.

Contraindications

Hypersensitivity to drug components.

Method of administration and dosage

Viferon ointment is used topically and externally

Herpetic infection: the ointment should be applied 3-4 times a day in a thin layer on the lesions and rubbed gently. The duration of therapy is from 5 to 7 days. It is recommended to start treatment when the first signs of the disease appear (redness, burning, itching). With recurrent herpes, it is advisable to start treatment in the prodromal period or when the first signs of relapse appear.

Influenza and other acute respiratory viral infections: a thin layer of ointment is applied to the mucous membrane of the nasal passages 3-4 times a day during the entire period of the disease. Frequency rate for children 1-2 years old - 3 times a day, 2-12 years old - 4 times a day.

Gel Viferon is used topically and externally

Combined ARVI therapy: gel (a strip up to 5 mm long) should be applied to the surface of the nasal mucosa, which must be pre-dried, and / or to the surface of the palatine tonsils, using a spatula or cotton swab for this, 3-5 times a day. The duration of the treatment course is 5 days, if necessary, therapy can be continued. For the prevention of acute respiratory viral infections during the rise in incidence, a strip of gel up to 5 mm is applied 2 times a day. The duration of Viferon's use is 14-28 days.

Complex therapy of recurrent stenosing laryngotracheobronchitis: a strip of gel up to 5 mm long should be applied to the surface of the tonsils. In the acute period of the disease (first 5-7 days) - 5 times a day, then within 21 days - 3 times a day. To prevent the disease, the gel is used for 21-28 days 2 times a day, it is recommended to repeat the courses 2 times a year.

Complex therapy of acute and chronic recurrent herpes infection (when the first signs of the disease appear): a strip of gel up to 5 mm should be applied with a cotton swab / cotton swab or spatula on the affected surface, previously dried, 3-5 times a day for 5-6 days. The duration of the course can be increased until the disappearance of clinical manifestations.

Complex therapy of herpetic cervicitis: 1 ml of gel with a cotton swab should be applied 2 times a day to the surface of the cervix, which must first be cleared of mucus. The duration of the drug is 7-14 days.

Gel on the surface of the tonsils should be applied half an hour after eating, on the nasal mucosa - after cleaning the nasal passages. When Viferon is applied to the affected areas of the mucous membranes and skin, a thin film is formed within 30-40 minutes, on which the next dose is subsequently applied. If desired, the film can be washed off with water or peeled off.

Viferon suppositories are used rectally

Complex therapy of acute respiratory viral infections:

• Adults and children from 7 years old - every day for 5 days (according to indications, possibly longer). 2 times a day with a break of 12 hours, 1 suppository 500,000 IU;
• Children under 7 years of age, including newborns and premature infants with gestational age of 34 weeks - 1 suppository daily 150,000 IU 2 times a day with an interval of 12 hours for 5 days (if indicated, treatment can be continued with an interval of 5 days);
• Premature infants with gestational age up to 34 weeks - 1 suppository of 150,000 IU daily, 3 times a day with an interval of 8 hours for 5 days (according to indications, treatment can be continued with an interval of 5 days).

Complex therapy of infectious and inflammatory diseases (sepsis, meningitis, intrauterine infections, including CMV infection, chlamydia, herpes, candidiasis, enterovirus infection) of newborn children, incl. premature babies with gestational age: over 34 weeks - daily 1 suppository 150,000 IU 2 times a day with an interval of 12 hours, up to 34 weeks - 1 suppository daily 150,000 IU 3 times a day with an interval of 8 hours. The treatment course is 5 days.

Depending on the indications, treatment is recommended to be carried out in courses with a break of 5 days:

• Sepsis - 2-3 courses;
• CMV infection - 2-3 courses;
• Herpetic infection - 2 courses;
• Meningitis - 1-2 courses;
• Mycoplasmosis, candidiasis, incl. visceral - 2-3 courses;
• Enterovirus infection - 1-2 courses.

In the presence of clinical indications, treatment can be continued.

Complex therapy of chronic viral hepatitis B, C, D: 10 days Viferon is used daily 2 times a day every 12 hours, then 6-12 months - 3 times a week every other day. The duration of therapy is determined by laboratory parameters and clinical efficacy. The daily dose is:

• Adults - 2 suppositories of 3,000,000 IU each;
• Children from 7 years old - 5,000,000 IU per 1 m2 of body surface area;
• Children 1-7 years old - 3,000,000 IU per 1 m2 of body surface area;
• Children 6-12 months - 500,000 IU;
• Children under 6 months - 300,000-500,000 IU.

Chronic viral hepatitis of pronounced activity and cirrhosis of the liver: before hemosorption and / or plasmapheresis, children under 7 years of age are recommended to use Viferon daily at 150,000 IU, children over 7 years old - 500,000 IU 2 times a day with a break of 12 hours for 14 days.

Complex therapy of infectious and inflammatory diseases of the urogenital tract (mycoplasmosis, ureaplasmosis, human papillomavirus infection, chlamydia, CMV infection, gardnerellosis, trichomoniasis, recurrent vaginal candidiasis, bacterial vaginosis): for adults - 5-10 days daily, 1 500000 IU suppository of Vifer. Frequency rate of application - 2 times a day (every 12 hours). In the presence of clinical indications, treatment can be continued. According to the same scheme, in the first 10 days of treatment, Viferon is prescribed to pregnant women after 14 weeks of gestation. In the next 10 days, the drug is prescribed 1 suppository 2 times a day with a break of 12 hours every 4th day. Further - every 28 days until delivery, 1 suppository 150,000 IU 2 times a day with the same interval daily for 5 days. If necessary, before delivery (from 38 weeks of gestation), 1 suppository 500,000 IU 2 times a day is prescribed for 10 days.

Recurrent or primary herpetic infection of the skin and mucous membranes, localized form (moderate and mild): the recommended single dose for adults for 10 days is 1,000,000 IU, for pregnant women from the 2nd trimester - 500,000 IU. The drug is used daily, 2 times a day (every 12 hours). In the presence of clinical indications, therapy can be continued. In the future, Viferon can be used for pregnant women according to the treatment regimen for infectious and inflammatory diseases of the urogenital tract.

Side effects

Viferon in the form of an ointment is well tolerated in most cases. Side effects when applied to the nasal mucosa are usually transient and mild and disappear on their own after discontinuation of the drug.

In extremely rare cases, when using the gel in patients with hypersensitivity, local allergic reactions may develop. When they appear, treatment is stopped.

When using Viferon suppositories, in some cases, the development of allergic reactions (itching, skin rashes) is possible. These phenomena are reversible and disappear 72 hours after stopping therapy.

special instructions

An opened tube with ointment can be stored in the refrigerator for 1 month, with a gel - 2 months.

Viferon in the form of suppositories for pregnant women can be used starting from the 14th week of pregnancy.

Drug interactions

Viferon combines well with all drugs used in the treatment of viral and other diseases (chemotherapy, antibiotics, glucocorticosteroids).

Analogs

Viferon's analogs are: Infagel, Vitaferon, Genferon, Laferon, Laferobion, Anaferon, Kipferon, Grippferon.

Terms and conditions of storage

Store in a dark, dry place out of reach of children at a temperature of 2-8 ° C.

The shelf life of the drug in the form of a gel and ointment is 1 year, suppositories - 2 years.

Terms of dispensing from pharmacies

Available without a prescription.

Viferon: prices in online pharmacies

Drug name Price Pharmacy

Viferon 36000 IU / g gel for local and external use 12 g 1 pc. 113 RUB Buy

Viferon 40,000 IU / g ointment for local and external use 12 g 1 pc. 170 RUB Buy

Viferon gel for local and outdoor. approx. 36000 IU / ml 12g 10ml 196 r Buy

Viferon ointment 40 thousand. IU / g 12g 207 r Buy

Viferon 150,000 IU rectal suppositories 10 pcs. 226 r Buy

Viferon rectal suppositories. 150 thousand IU 10 pcs. RUB 311 Buy

Viferon 500000 IU rectal suppositories 10 pcs. 345 r Buy

Viferon rectal suppositories. 500 thousand ME 10 pcs. 423 r Buy

Viferon 1000000 IU rectal suppositories 10 pcs. 492 RUB Buy

Viferon rectal suppositories. 1 mln. ME 10 pcs. 572 r Buy

Viferon 3,000,000 IU rectal suppositories 10 pcs. RUB 924 Buy

Viferon rectal suppositories. 3 mln. ME 10 pcs. 1015 RUB Buy

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Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!