Mometasone
Instructions for use:
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. Drug interactions
- 12. Analogs
- 13. Terms and conditions of storage
- 14. Terms of dispensing from pharmacies
- 15. Reviews
- 16. Price in pharmacies
Prices in online pharmacies:
from 264 rub.
Buy
Mometasone is a synthetic glucocorticosteroid (GCS) drug for topical use with anti-inflammatory, anti-allergic, anti-exudative and antipruritic effects.
Release form and composition
Dosage forms:
- Ointment 0.1% (15 g in a tube);
- Cream 0.1% (15 g in a tube).
The active ingredient of Mometasone is mometasone furoate, in 1 g of ointment or cream - 1 mg.
Auxiliary components:
- Ointment: propylene glycol monopalmitostearate, hexylene glycol, white wax, diluted phosphoric acid, white soft paraffin (white petrolatum), purified water;
- Cream: glyceryl monostearate 40-55, macrogol 20 cetostearyl ether, hexylene glycol, cetostearyl alcohol, titanium dioxide (E171), starch octenyl succinate aluminum salt, white soft paraffin (white petrolatum), diluted phosphoric acid, diluted wax, white wax,
Pharmacological properties
Pharmacodynamics
Mometasone furoate is a synthetic glucocorticosteroid. It has anti-inflammatory, anti-exudative and antipruritic effects.
Glucocorticosteroids induce the release of lipocortins, special proteins that inhibit phospholipase A 2. Lipocortins control the biosynthesis of leukotrienes and prostaglandins (inflammatory mediators) by inhibiting the release of arachidonic acid, which is a common precursor of these inflammatory mediators.
Pharmacokinetics
Mometasone is practically not absorbed. 8 hours after applying the drug to intact skin (without using an occlusive dressing), no more than 0.7% of mometasone is found in the patient's blood.
Indications for use
- Dermatoses with itching and inflammation, amenable to GCS treatment;
- Chronic eczema, atopic and seborrheic dermatitis, psoriasis and other pathologies with symptoms of hyperkeratosis.
Contraindications
- Age up to 2 years;
- Conditions after a recent injury or surgery on the nose (until the moment of complete healing);
- Breastfeeding period;
- Diaper dermatitis;
- Hypersensitivity to corticosteroids and drug components.
Instructions for use of Mometasone: method and dosage
Mometasone cream and ointment are intended for topical use.
The product should be applied in a thin layer to the affected skin once a day.
The scheme and duration of treatment is prescribed by the doctor based on clinical indications.
Side effects
- Rarely: dryness and irritation of the skin, folliculitis, acne-like rash, perioral dermatitis, hypertrichosis, secondary infection, hypopigmentation, prickly heat, contact allergic dermatitis, striae;
- Others: against the background of the use of occlusive dressings - burning, itching, rosacea, skin atrophy.
If signs of adverse reactions appear at the site of application of the drug, the use of Mometasone should be canceled.
Overdose
In case of an overdose of the drug, symptoms of inhibition of the function of the hypothalamic-pituitary-adrenal system, including secondary adrenal insufficiency, are observed.
In case of overdose, symptomatic treatment is prescribed. If necessary, the water-electrolyte balance is corrected and the drug is discontinued. With long-term treatment, the abolition of Mometasone should be carried out gradually.
special instructions
Avoid getting Mometasone cream or ointment in eyes.
Do not apply the drug to the face, in the armpit and groin folds.
Systemic absorption can cause reversible inhibition of the hypothalamic-pituitary-adrenal system, the development of glucosuria, hyperglycemia, Cushing's syndrome; with prolonged use in large areas - withdrawal syndrome.
Due to the risk of developing systemic complications, Mometasone is not recommended to be applied under waterproof underwear or occlusive dressings.
With a large affected area or the need to use occlusive dressings, treatment should be accompanied by monitoring the function of the hypothalamic-pituitary-adrenal system. This will allow diagnosing the initial signs of systemic action of the drug and in time to increase the interval between applying the drug or cancel its use.
If, during therapy, the development of infectious complications of bacterial or fungal genesis occurs, the patient should temporarily stop using Mometasone and consult a doctor for the appointment of appropriate therapy.
Treatment of children should be carried out under regular medical supervision, since the risk of developing atrophic skin lesions, Cushing's syndrome and functional disorder of the hypothalamic-pituitary-adrenal system in them is much higher than in adults.
If there is no clinical effect after 2 weeks of using Mometasone, you should consult a doctor to clarify the diagnosis.
Application during pregnancy and lactation
There is insufficient data on the safety of the drug in pregnant and lactating women.
Since glucocorticosteroids are able to penetrate the placental barrier and have a negative effect on the embryonic development of the fetus, the use of Mometasone during pregnancy is possible only in small doses and for a short time.
With prolonged therapy with glucocorticosteroids and / or the use of the drug in large doses, breastfeeding should be discontinued, since glucocorticosteroids are excreted in breast milk.
Pediatric use
According to the instructions, Mometasone is contraindicated in children under 2 years of age, since there is insufficient data on its safety and effectiveness at this age.
Drug interactions
The drug is incompatible with alkali-containing agents.
Analogs
Analogues of Mometasone are: Momat, Nasonex, Elokom, Uniderm, Twistheiler.
Terms and conditions of storage
Keep out of reach of children at temperatures up to 25 ° C.
Terms of dispensing from pharmacies
Dispensed by prescription.
Reviews about Mometasone
The drug is effective for various dermatoses, which is confirmed by reviews of Mometasone. The result of the treatment is noticeable after 10 days of applying the cream or ointment. It should be noted that some patients talk about addiction to the drug, as a result of which there may be a need to increase the dose. It also mentions skin burns when the treated areas are exposed to ultraviolet rays.
The price of Mometasone in pharmacies
To date, the price of Mometasone is unknown, since the drug is very rare in pharmacies. Average prices for similar medicinal products with the same active ingredient are as follows:
- Momat, cream 0.1%, 5 g - 160 rubles;
- Nazonex, spray 50 mcg / dose, 60 doses - 450 rubles;
- Uniderm, cream 0.1%, 15 g - 180 rubles;
- Elokom, cream 0.1%, 15 g - 330 rubles.
Mometasone: prices in online pharmacies
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Drug name Price Pharmacy |
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Mometasone Sandoz nasal spray. 50mcg / dose vial 10g 60 doses 264 r Buy |
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Mometasone Sandoz 50 mcg / dose 60 doses nasal spray dosed 10 g 1 pc. 264 r Buy |
|
Mometasone Sandoz 50 μg / dose 140 doses nasal spray dosed 18 g 1 pc. 276 r Buy |
|
Mometasone Sandoz nasal spray. 50mcg / dose vial 18g 140 doses RUB 300 Buy |
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
