Cetirizine
Instructions for use:
- 1. Composition and form of release
- 2. Pharmacological action
- 3. Indications for use
- 4. Method of application and dosage regimen
- 5. Contraindications
- 6. Side effects
- 7. Overdose
- 8. Storage conditions
Prices in online pharmacies:
from 44 rubles.
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Cetirizine is an anti-allergic drug. Blocker of histamine H1 receptors.
Composition and form of release
The drug is available in three dosage forms:
- White, oblong tablets, each containing 10 mg of cetirizine dihydrochloride. Auxiliary components: lactose monohydrate, microcrystalline cellulose, titanium dioxide, colloidal silicon dioxide, magnesium stearate. In packs of 7 or 10 tablets.
- Colorless, transparent oral drops containing 10 mg of cetirizine dihydrochloride in 1 ml. Auxiliary components: sodium acetate trihydrate, benzoic acid, propylene glycol, glycerol 85%, distilled water. In dropper bottles of 10 or 20 ml.
- Colorless, transparent, banana-flavored syrup for oral administration, containing 1 mg cetirizine dihydrochloride in 1 ml. Additional components: glycerol 85%, sodium saccharin, banana flavor, sorbitol 70%, acetic acid 20%, propyl parahydroxybenzoate, sodium acetate, methyl parahydroxybenzoate, propylene glycol. Available in 75 or 150 ml dark glass bottles, complete with a measuring spoon.
Analogues of Cetirizine are the following drugs: Alercetin, Anallergin, Zodak, Tsetrin, Cetirinax.
Pharmacological action of Cetirizine
According to the instructions, Cetirizine is a histamine H1 receptor blocker and has a pronounced antiallergic effect on the body.
The use of Cetirizine in the recommended dosages has practically no sedative effect, as well as antiserotonin and anticholinergic. Eases the course of allergies and prevents its development. According to reviews, Cetirizine has antiexudative and antipruritic effects.
Influences allergic reactions at an early stage, reduces the migration of inflammatory cells. In the late stage, allergy inhibits the release of mediators. Reduces capillary permeability, relieves tissue edema and smooth muscle spasms. Removes skin reactions to the introduction of histamine, specific allergens and cooling (for example, with cold urticaria).
In patients with bronchial asthma, Cetirizine, according to reviews, significantly reduces the hyperreactivity of the bronchial tree, which occurs due to the release of histamine.
According to the instructions, Cetirizine has a therapeutic effect about an hour after administration.
Indications for the use of Cetirizine
According to the instructions, Cetirizine is indicated in the following cases:
- urticaria, including chronic idiopathic;
- allergic conjunctivitis;
- seasonal and perennial allergic rhinitis (as symptomatic treatment);
- dermatoses occurring with itching, including neurodermatitis, atopic dermatitis.
Dosing and Administration of Cetirizine
1. Tablets
The drug or analogues of Cetirizine in tablet form are taken by children over twelve years of age and adults, one tablet per day, preferably before bedtime.
Children aged six to twelve years old, with a body weight of less than 30 kg, take half a tablet in the evening, with a body weight of more than 30 kg - one tablet at bedtime. It is allowed to divide the pill intake in half (half a tablet in the morning, half a tablet in the evening).
2. Syrup
Cetirizine syrup is prescribed for children aged two to twelve years, weighing less than 30 kg, at a dosage of 5 ml per day, with a weight of more than 30 kg - 10 ml per day.
Children over twelve years old and adults take 10 ml of Cetirizine syrup per day.
3. Drops
In the form of drops, Cetirizine is taken by children aged one to two years at a dosage of 2.5 mg (5 drops) per day. At the age of two to six years, the dosage is 5 mg (10 drops) per day. At the age of six to twelve years, children take a drug or analogue of Cetirizine, 10 mg (20 drops) per day.
Children over the age of twelve and adults usually take 20 drops (10 mg) per day. The drug is taken in the evening.
Reception of Cetirizine according to reviews for renal failure requires a halving of the dosage.
Care should be taken to select the dosage in case of impaired liver function, especially in combination with renal failure.
On average, the duration of treatment for seasonal allergies is 3-6 weeks, and for short-term allergies, it is enough to take the drug for one week.
The duration of treatment with Cetirizine in children over the age of six is up to one month.
Contraindications
The use of Cetirizine is contraindicated in the following cases:
- pregnancy and breastfeeding;
- hypersensitivity;
- severe kidney disease.
According to the instructions, Cetirizine should be prescribed with caution to elderly people, since in this category of patients, a decrease in glomerular filtration is possible. In addition, care must be taken when prescribing the drug for chronic pyelonephritis of moderate and severe stages.
The drug in the form of drops is intended for children over one year of age. In the form of a syrup, the drug can be taken by children over two years old. It is recommended to prescribe tablets from the age of seven.
During the use of Cetirizine, it is not recommended to take drugs that depress the central nervous system, as well as ethanol.
Side effects of Cetirizine
According to reviews, Cetirizine can cause the following side effects:
- Allergic reactions: urticaria, skin rash, angioedema, pruritus.
- CNS: drowsiness, dizziness, headache, migraine, agitation, fatigue.
- Digestive system: dyspepsia, dry mouth.
Positive reviews about Cetirizine indicate that mainly the drug is well tolerated by patients. Usually side effects are transient.
Overdose
An overdose of Cetirizine causes the following symptoms: lethargy, drowsiness, tachycardia, weakness, headache, urinary retention, irritability, fatigue.
In this case, it is necessary to carry out symptomatic treatment, make a gastric lavage and take activated charcoal.
Storage conditions for Cetirizine
Cetirizine is stored in a dry place at room temperature for no longer than three years.
The drug in the form of drops after opening the bottle cannot be used for more than six months, and the syrup must be used within three months from the moment of opening.
Cetirizine: prices in online pharmacies
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Drug name Price Pharmacy |
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Cetirizine 10 mg film-coated tablets 10 pcs. RUB 44 Buy |
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Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
