Ketonal - Instructions, Application, Purpose

2024 Author: Rachel Wainwright | [email protected]. Last modified: 2023-12-15 07:39

Ketonal

Instructions for use:

1. 1. Pharmacological action
2. 2. Indications for use
3. 3. Instructions for use
4. 4. Side effects
5. 5. Contraindications to use
6. 6. Additional information

Prices in online pharmacies:

from 77 rubles.

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Ketonal is a non-steroidal anti-inflammatory agent used in the symptomatic treatment of diseases of the musculoskeletal system, as well as to eliminate pain syndrome of various origins.

Pharmacological action of Ketonal

Ketonal has anti-inflammatory, analgesic and antipyretic properties.

The action of ketoprofen, the active substance of Ketonal, is due to the ability of the drug to increase the pain threshold by suppressing the synthesis of bradykinin, stabilize lysosomal membranes and delay the release of enzymes from them, which contribute to tissue destruction in chronic inflammation.

The maximum concentration of ketoprofen in the blood can be observed as early as 1.5-2 hours after using Ketonal tablets, 65-80 minutes after using rectal suppositories and after 5 minutes with intravenous administration.

About 90% of Ketonal is excreted by the liver, the half-life is about 2 hours. Delayed excretion of Ketonal in renal failure requires dose adjustment for patients with this disease.

Indications for use

The instruction recommends prescribing Ketonal for such degenerative and inflammatory diseases of the musculoskeletal system as:

• psoriatic arthritis (joint inflammation during psoriasis);
• rheumatoid arthritis (inflammatory and destructive lesion of large and small joints of the extremities);
• Bechterew's disease (persistent limitation of the mobility of the spine with possible involvement in the inflammatory process of internal organs);
• osteoarthritis (joint disease provoked by damage to their cartilage tissue);
• gouty arthritis (joint disease caused by the deposition of uric acid salts in various tissues).

The use of Ketonal is also advisable when:

• muscle pain;
• neuralgia (damage to peripheral nerves, accompanied by bouts of pain);
• ossalgia (pain resulting from damage to bone tissue);
• joint pain;
• tendinitis (inflammation around or inside a tendon);
• radiculitis (damage to the bundles of nerve fibers extending from the spinal cord);
• bursitis (inflammation of the joint capsules);
• adnexitis (inflammation of the uterine appendages);
• toothache and headache.

Ketonal is used as an analgesic for post-traumatic and postoperative pain syndrome, accompanied by inflammation, cancer, algodismenorrhea (soreness of menstruation), childbirth.

Instructions for the use of Ketonal

Ketonal is available in forms intended for oral administration: capsules, tablets, granules for suspension preparation.

For intramuscular injections, Ketonal is used as a solution or lyophilisate to prepare a solution. Only solution is injected intravenously. For external use Ketonal is available in the form of a gel, cream, spray and solution. Ketonal suppositories are intended for rectal use.

The instruction recommends taking capsules Ketonal three times a day, 1 pc. (50 mg), not exceeding a daily dose of 300 mg. For osteoarthritis and rheumatoid arthritis, 50 mg of the drug is taken four times a day. Ketonal should be washed down with a sufficient amount of milk or water, it is recommended to take the drug with meals. Ketonal Duo capsules containing 150 mg of ketoprofen are usually taken 1 pc. once a day, and if it is necessary to prescribe large doses of the drug for a short time, it is possible to increase the number of doses up to twice a day.

Ketonal tablets are usually prescribed 1-2 times a day, 1 pc. (150 mg), not exceeding a daily dose of 300 mg. The duration of treatment is two weeks, if necessary, the duration of the drug can be increased by the doctor. Ketonal tablets should be taken during or immediately after a meal with plenty of water.

Suppositories Ketonal, the use of which can be combined with taking tablets or capsules, are usually prescribed 1 pc. (With 100 mg) morning and evening.

Intramuscular Ketonal injections are usually prescribed 1-3 times a day, 1 ampoule (100 mg). Intravenous Ketonal injections should only be given in a hospital setting. With intermittent administration, 1-2 ampoules of the drug are diluted with 100 ml of "saline" and administered within half an hour or an hour. With continuous administration, the same amount of Ketonal is diluted in 500 ml of "saline" or glucose and injected over 8 hours. Repeated intravenous Ketonal injections are given after 8 hours.

Ketonal gel and cream are intended for external topical use. These forms of the drug are used for pain in joints and muscles that were caused by damage or injury, as well as for tendovaginitis (inflammation of the tendon and its sheath). Ketonal cream should be applied to the affected areas 2 times a day, and the gel - 1 or 2 times. The use of an occlusive dressing is not recommended. The maximum daily dose is 200 mg (10 cm of Ketonal cream). The duration of treatment is 7-10 days.

Side effects

According to the instructions, Ketonal can be the cause of the following undesirable phenomena:

• abdominal pain, stool disorders, vomiting, nausea, dry mouth, stomatitis, liver dysfunction, gastrointestinal bleeding;
• nervousness, fatigue, headache, migraine, sleep disturbance, dizziness, speech disorder;
• change in taste, tinnitus, conjunctivitis, blurred vision, pain in the eyes;
• arterial hypertension, tachycardia, peripheral edema;
• anemia, agranulocytosis, thrombocytopenia;
• nephrotic syndrome, impaired renal function, excess blood in the urine;
• allergic skin reactions, shortness of breath, bronchospasm, rhinitis, angioedema.

Ketonal cream and gel can provoke vascular edema, urticaria, skin rash, skin necrosis, dermatitis.

Contraindications to the use of Ketonal

The use of Ketonal is prohibited for hypersensitivity, "aspirin" asthma, peptic ulcer disease, ulcerative colitis, peptic ulcer, diverticulitis (protrusion of the intestinal wall), Crohn's disease (inflammation of the digestive tract, which can affect all its parts), blood clotting disorders, chronic kidney disease …

According to the instructions, Ketonal is contraindicated in children under 14 years old, pregnant and breastfeeding women.

Ketonal is prescribed with caution to patients suffering from bronchial asthma, anemia, alcoholism, alcoholic cirrhosis of the liver, liver failure, sepsis, diabetes mellitus, arterial hypertension, edema, stomatitis, blood diseases. The use of Ketonal by elderly patients should take place as directed and under the supervision of a physician.

Additional Information

Ketonal should be stored in a dark, dry place where the air temperature does not exceed 25 ^° C.

Ketonal: prices in online pharmacies

Drug name Price Pharmacy

Ketonal 100 mg film-coated tablets 10 pcs. 77 RUB Buy

Ketonal 50 mg capsules 25 pcs. 83 rbl. Buy

Ketonal capsules 50mg 25 pcs. RUB 97 Buy

Ketonal 50 mg / ml solution for intravenous and intramuscular administration 2 ml 10 pcs. 111 RUB Buy

Ketonal r / r i / v / and i / m int. 50mg / ml amp. 2ml No. 5 114 RUB Buy

Ketonal Active 40 mg granules for preparation of oral solution 12 pcs. 146 r Buy

Ketonal 100 mg film-coated tablets 20 pcs. 159 r Buy

Ketonal active granules for preparation of oral solution 40mg Pak. 1g 12 pcs. RUB 165 Buy

Ketonal tablets p.p. 100mg 20 pcs. 171 r Buy

Ketonal DUO 150 mg modified release capsules 30 pcs. 199 RUB Buy

Reviews Ketonal DUO 199 RUB Buy

Ketonal suppositories rectal. 100mg 12 pcs. 209 RUB Buy

Ketonal 100 mg rectal suppositories 12 pcs. 209 RUB Buy

Ketonal solution for intravenous and intramuscular injection 50mg / ml 2ml 10 pcs. RUB 218 Buy

Ketonal DUO capsules with modif. release 150mg 30 pcs. Lek RUB 218 Buy

Ketonal 150 mg sustained release tablets 20 pcs. 264 r Buy

Ketonal cream 5% 30g 269 r Buy

Ketonal 5% cream for external use 30 g 1 pc. 269 r Buy

Ketonal 2.5% gel for external use 50 g 1 pc. RUB 291 Buy

Ketonal gel 2.5% 50g 292 r Buy

Ketonal 5% cream for external use 50 g 1 pc. 365 RUB Buy

Ketonal cream 5% 50g 397 r Buy

Ketonal gel 2.5% 100g 409 r Buy

Ketonal 2.5% gel for external use 100 g 1 pc. 409 r Buy

Ketonal outdoor cream approx. 5% tube 100g 521 RUB Buy

Ketonal 5% cream for external use 100 g 1 pc. 521 RUB Buy

Ketonal cream for planks approx. 5% 50g (tube) promo pack 1 + 1 585 RUB Buy

Ketonal 50 mg / ml solution for intravenous and intramuscular administration 2 ml 50 pcs. 894 r Buy

Ketonal solution for intravenous and intramuscular injection 50mg / ml 2ml 50 pcs. 999 RUB Buy

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Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!