Acylact
Acylact: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. Drug interactions
- 12. Analogs
- 13. Terms and conditions of storage
- 14. Terms of dispensing from pharmacies
- 15. Reviews
- 16. Price in pharmacies
Latin name: Acilact
ATX code: A07FA01
Active ingredient: Lactobacillus acidophilic (Lactobacillus acidophilus)
Manufacturer: Lanafarm, LLC (Russia); Vitapharma Firma, CJSC (Russia)
Description and photo update: 2019-21-08
Prices in pharmacies: from 144 rubles.
Buy
Acylact is a drug used to treat diseases of the female genital area, intestines and oral cavity caused by microflora disorders.
Release form and composition
- tablets: round, smooth with flat or slightly convex surfaces, from different shades of beige to yellowish-gray, marbling of the surface is allowed, with a characteristic odor (20, 30 or 60 pcs. in polypropylene cans, 20 or 30 pcs. in bottles; in a pack of cardboard 1 can of propylene / bottle);
- lyophilisate for preparation of a suspension for oral administration and topical application [50 million CFU (5 doses) in vials, in a cardboard box 10 vials];
- vaginal suppositories: cone-shaped or cylindrical, from different shades of beige to yellowish-gray, non-uniformity of coloration in the form of marbling of the surface or inclusions and / or staining of the tip of the suppository in a pale yellow or light brown color, have a characteristic smell of confectionery fat (1 piece. in a blister contour package, in a pack of cardboard 10 packs; 5 pcs. in a blister contour packing, in a pack of cardboard 2 packs; 10 pcs. in a contoured cell, in a cardboard box 1 package)
Composition of 1 tablet (5 doses):
- active substance: acidophilic lactobacilli (live strains, lyophilized in a cultivation medium with the addition of a protective sucrose-gelatin-milk medium, compressed into one tablet) ≥ 5 × 10 7 CFU (colony-forming units);
- auxiliary components: calcium stearate, lactose, talc.
1 vial of lyophilisate contains acidophilic lactobacilli, live strains, lyophilized in the culture medium (5 doses) ≥ 5 × 10 7 CFU.
Composition of 1 vaginal suppository:
- active substance: microbial mass of live antagonistically active lactobacilli strains Lactobacillus acidophilus NK1, K3Sh24 and 100ash - 10 7 CFU;
- auxiliary components: confectionery fat, solid petroleum paraffin, emulsifier.
Pharmacological properties
Acylact has a high degree of antagonistic activity against pathogenic and opportunistic microflora, including staphylococci, shigella, enteropathogenic Escherichia coli, Proteus. Due to these properties, the drug has a corrective effect in violations of the bacteriocenosis of the intestine, oral cavity and female genital area.
Indications for use
Diseases of the oral cavity (lyophilisate and tablets):
- aphthous stomatitis, glossitis, necrotizing ulcerative gingivitis, other inflammation of the oral mucosa;
- pathologies of the oral mucosa accompanying such systemic diseases as erythema multiforme exudative, lichen planus, Sjogren's disease;
- multiple caries, periodontitis, galvanism and other diseases of the oral cavity associated with dysbiosis;
- the period of preparation for planned maxillofacial surgical interventions (for the prevention of complications of a purulent-inflammatory nature).
Diseases of the gastrointestinal tract (lyophilisate and tablets):
- foodborne infections of unknown etiology or caused by opportunistic microbes, acute intestinal infections, rotavirus gastroenteritis;
- prolonged intestinal disorders, especially in early childhood;
- prolonged / chronic colitis and enterocolitis, both infectious and non-infectious etiology, with microflora disturbance;
- nonspecific ulcerative colitis in adults in moderate and mild form;
- weakness, frequent illness in children and adults with symptoms of dysbiosis, including accompanied by a state of immunodeficiency;
- atopic dermatitis in children with intestinal dysbiosis (as part of complex therapy).
Diseases of the female genital tract (suppositories and lyophilisate):
- colpitis (vaginitis), except for Trichomonas, gonococcal and candidal etiology (Acilact is prescribed after the completion of antibiotic therapy as an independent drug);
- vaginal dysbiosis due to inflammation of the body, appendages and cervix (after the completion of antibiotic therapy);
- the period of preparation for planned gynecological surgical interventions in order to prevent postoperative infections;
- the period of prenatal preparation of pregnant women from the risk group for the development of purulent septic postpartum complications, in order to prevent / treat vaginal dysbiosis.
Contraindications
All forms of release of Acylact are contraindicated for use in cases of identified hypersensitivity to their components.
Suppositories are not recommended for patients with vulvovaginal candidiasis.
Instructions for use of Acylact: method and dosage
Depending on the disease, various dosage forms of Acylact are used locally, orally and intravaginally.
When using a lyophilisate to prepare a suspension, the contents of the vial must be dissolved in boiled water at room temperature at the rate of 1 teaspoon of water per 1 dose of Acylact. A small amount of measured water is added to the medicine bottle and shaken well. The powder dissolves in an average of 5 minutes, resulting in a beige homogeneous suspension, which must be mixed in the water remaining in the glass. It should be borne in mind that the prepared solution cannot be stored.
Depending on the severity of dysbacteriosis and the clinical form of the disease, the doctor determines the daily dose and method of application of Acylact.
The drug is used as an aqueous suspension for rinsing after meals for the following diseases of the oral mucosa:
- Glossitis: usually prescribed for two weeks, 5 doses up to 3 times a day;
- Necrotizing ulcerative gingivitis and recurrent aphthous stomatitis: take the drug for two weeks, 5 doses up to 3 times a day, conduct two courses of treatment with Acylactom with a break a week;
- Pathological processes in the oral cavity caused by such systemic diseases as Sjogren's disease, lichen planus and exudative erythema multiforme: two courses of 2 weeks, 10 doses per day, divided into 4 doses, with a break between courses of at least 7 days.
For intestinal disorders, oral administration of Acilact is most effective half an hour before meals. Children under the age of six months are prescribed 5 doses per day, divided into 2 doses; children over 6 months and adults - 5 doses 2-3 times a day. The drug in acute inflammatory processes is taken for a week, with recurrent and protracted forms of the disease - from two to three weeks.
With atopic dermatitis in children, accompanied by a violation of the normal intestinal microflora, several courses of Acilact are prescribed, 5 doses per day for 20-25 days, with intervals of two months.
Vaginal suppositories Acylact are used for diseases of the female genital organs, 1 suppository twice a day for 5-10 days. You can also carry out irrigation with an aqueous suspension of the lyophilisate to prepare a suspension or introduce a swab soaked in it.
Side effects
Usually Acylact does not cause side effects.
Overdose
There is no data.
special instructions
Vaginal suppositories Acilact should be used immediately after completion of the antifungal treatment of vulvovaginal candidiasis.
Influence on the ability to drive vehicles and complex mechanisms
According to the instructions, Atzilact does not affect the concentration of attention and the speed of psychomotor reactions.
Application during pregnancy and lactation
Since lactobacilli represent the normal human microflora, preparations made on their basis are allowed to be used during pregnancy and during breastfeeding (lactation).
Pediatric use
In pediatric practice, Acylact is used in recommended doses, according to indications.
Drug interactions
No clinically significant interaction of Lactobacillus acidophilus with other medicinal substances / preparations has been established. Acylact tablets, lyophilisate and suppositories can be used simultaneously with antiviral, antibacterial and immunomodulatory drugs.
It is not recommended to simultaneously apply intravaginally Acilact suppositories and antibacterial drugs.
Corrective therapy with Acylactom can be prescribed after a course of specific bacteriophages designed to eliminate opportunistic microflora.
Analogs
Analogs of Acylact are Lactozhinal, Lactobacterin, Lactonorm, Ekofemin, Atsilakt-BIO, Biobacton, etc.
Storage conditions and periods
Store at 2-8 ° C.
Expiration date - 1 year.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Acylact
According to reviews, Acylact in the form of suppositories and tablets is an excellent substitute for expensive eubiotics. The drug is clinically effective, easy to use and, importantly, affordable.
Complaints are caused by the insufficiently good quality of suppositories, they often crumble, melt quickly and are inconveniently packaged, it is difficult to get a candle out of the cell packaging.
The price of Atzilact in pharmacies
Approximate price of Acylact: vaginal suppositories, 10 pcs. in the package 95-115 rubles; tablets of 5 doses, 30 pcs. in the package - 285–363 rubles.
Atzilakt: prices in online pharmacies
|
Drug name Price Pharmacy |
|
Acylact suppositories, vaginal suppositories 10 pcs. 144 RUB Buy |
|
Reviews Acylact (candles) 144 RUB Buy |
|
Acylact (suppositories) 1.3 g vaginal suppositories 10 pcs. 173 r Buy |
|
Acylact suppositories, vaginal suppositories 10 pcs. RUB 176 Buy |
|
Reviews Acylact (candles) RUB 176 Buy |
|
Acylact lyophilisate for preparation of a solution for oral administration and topical administration 10 pcs. 251 RUB Buy |
|
Acylact vaginal suppositories 10 pcs. Vitapharma 302 RUB Buy |
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
