Ambrosan

2024 Author: Rachel Wainwright | [email protected]. Last modified: 2023-12-15 07:39

Instructions for use:

1. Release form and composition
2. Indications for use
3. Contraindications
4. Method of application and dosage
5. Side effects
6. Special instructions
7. Drug interactions
8. Analogs
9. Terms and conditions of storage
10. Terms of dispensing from pharmacies

Ambrosan is a mucolytic drug with a secretolytic, secretomotor and expectorant effect.

Release form and composition

Tablets: round, flat, almost white, with a risk (10 pcs. In blisters, in a cardboard box 2 blisters);
Oral solution: transparent, colorless or light yellow (50 and 100 ml each in dark glass dropper bottles, in a cardboard box 1 bottle complete with a measuring cup).

The active substance is ambroxol hydrochloride:

1 tablet - 30 mg;
1 ml of solution - 7.5 mg.

Auxiliary components of tablets: microcrystalline cellulose, magnesium stearate, copovidone, lactose monohydrate.

Additional substances of the solution: benzalkonium chloride 50% solution, citric acid monohydrate, sodium cyclamate, sodium chloride, glycerol, sodium hydrogen phosphate dodecahydrate, sorbitol 70% solution, purified water.

Indications for use

Ambrosan is a drug for the treatment of infectious and inflammatory diseases of the respiratory system, accompanied by the formation of viscous sputum:

Chronic obstructive pulmonary disease;
Acute and chronic bronchitis;
Pneumonia;
Bronchiectasis;
Bronchial asthma with obstruction of sputum discharge.

Contraindications

For both dosage forms:

I trimester of pregnancy;
Breastfeeding period;
Hypersensitivity to Ambrosan components.

Additionally for tablets:

Children under 6 years old;
Rare hereditary diseases such as glucose-galactose malabsorption, galactose intolerance and lactase deficiency.

Carefully:

II and III trimesters of pregnancy;
Peptic ulcer and 12 duodenal ulcer;
Renal and / or hepatic impairment.

Method of administration and dosage

Ambrosan should be taken orally, with food, with a little liquid.

Recommended doses:

Adults and adolescents over 12 years old: the first 2-3 days - 1 tablet or 4 ml of solution 3 times a day, then - 1 tablet / 4 ml of solution 2 times a day or ½ tablet / 2 ml of solution 3 times a day;
Children 6-12 years old: ½ tablet or 2 ml of solution 2-3 times a day;
Children 2-6 years old: 1 ml of solution 3 times a day;
Children under 2 years of age: 1 ml of solution 2 times a day.

Maximum daily doses of ambroxol:

Adults and adolescents over 12 years old - 90 mg (3 tablets or 12 ml of solution);
Children 6-12 years old - 45 mg (1.5 tablets or 6 ml of solution);
Children 2-6 years old - 22.5 mg (3 ml of solution);
Children under 2 years old - 15 mg (2 ml of solution).

Unless otherwise prescribed by the doctor, the duration of treatment is no more than 5 days.

Side effects

Allergic reactions: rarely (> 1/10 000, <1/1000) - urticaria, skin rash, allergic dermatitis; very rarely (<1/10 000) - anaphylactic shock, angioedema;
From the digestive system: rarely - constipation or diarrhea; with prolonged use in high doses - nausea, vomiting, gastralgia;
From the nervous system: rarely - headache, weakness;
From the genitourinary system: rarely - dysuria;
Respiratory system: rarely - dryness of the oral mucosa and respiratory tract, rhinorrhea.

special instructions

Ambroxol does not adversely affect the speed of reactions and the ability to concentrate.

With caution, the drug should be prescribed in violation of bronchial motility, which is accompanied by an increased formation of surfactant.

Drug interactions

Ambrosan should not be used concurrently with antitussive drugs, as they reduce coughing and make it difficult to remove phlegm.

Ambroxol increases the penetration of erythromycin, cefuroxime, doxycycline and amoxicillin into the bronchial secretions.

Analogs

Ambrosan analogs are: Ambrobene, Ambroxol, Bronchorus, Lazolvan, Mucobron, Ambrohexal, Neo-Bronchol, Flavamed, Ambroxol, Haliksol.

Terms and conditions of storage

Store in a place protected from light, dry, out of reach of children, in compliance with the temperature regime from 15 to 25 ºС.

Shelf life of tablets - 3 years, solution - 2 years.

Terms of dispensing from pharmacies

Available without a prescription.

Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!