Potassium permanganate
Potassium permanganate: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Drug interactions
- 11. Analogs
- 12. Terms and conditions of storage
- 13. Terms of dispensing from pharmacies
- 14. Reviews
- 15. Price in pharmacies
Latin name: Potassium permanganate
ATX code: D08AX06
Active ingredient: Potassium permanganate (Potassium permanganate)
Producer: Tatkhimfarmpreparaty, Yaroslavl Pharmaceutical Factory, Update PFC, Tula Pharmaceutical Factory, Usolye-Sibirskiy KhFZ (Russia)
Description and photo update: 2019-12-08
Prices in pharmacies: from 40 rubles.
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Potassium permanganate is an antiseptic preparation for external and local use.
Release form and composition
The dosage form of Potassium permanganate is a powder for preparing a solution for external use: crystals or crystalline fine powder of red or dark violet color with a metallic luster (3, 5 or 15 g in bags, cans or bottles, in a cardboard box 1 pc.; 3, 5 or 15 g in heat-sealable bags, in a cardboard box 10 bags; 15 g in plastic bags, in a cardboard box 1 package; 3 or 5 g in glass test tubes, in a cardboard box 1 test tube).
The active substance is potassium permanganate.
Pharmacological properties
Pharmacodynamics
The drug has an antiseptic and deodorant effect. In the process of reducing potassium permanganate, manganese oxide forms albumin (complex compounds) with proteins, therefore, in concentrated solutions, the drug has a tanning, cauterizing, irritating effect, and in low concentrations it has an astringent effect.
Potassium permanganate is able to neutralize some poisons, so it is included in solutions that are used to wash the stomach in case of poisoning. It is also effective in treating ulcers and burns.
When ingested, the drug is absorbed and has a hematotoxic effect (causes the development of methemoglobinemia).
Potassium permanganate is included in list No. 4 of the list of narcotic drugs, psychotropic substances and their precursors subject to control in the Russian Federation.
Indications for use
The use of the drug is indicated for washing wounds, burns, ulcers; douching and washing in urology and gynecology; gastric lavage in case of poisoning with ingested alkaloids (including morphine, aconitine) or phosphorus.
Contraindications
The therapeutic use of the drug is contraindicated in patients with hypersensitivity to potassium permanganate.
Instructions for the use of Potassium permanganate: method and dosage
A solution of potassium permanganate is used topically and topically.
The recommended concentration of Potassium permanganate in the form of solutions:
- Wound washing: 0.1-0.5%;
- Gargle: 0.01-0.1%;
- Lubrication of burn and ulcerative surfaces: 2-5%;
- Douching and washing (in urological and gynecological practice): 0.02-0.1%;
- Gastric lavage: 0.02-0.1%.
Side effects
At high concentrations, potassium permanganate can cause side effects in the form of damage to surrounding tissues.
Overdose
In case of an overdose of the drug, the following symptoms may develop:
- sharp pain in the mouth, along the esophagus, in the abdomen;
- diarrhea, vomiting;
- swelling of the mucous membrane of the oral cavity and pharynx, staining this area in a dark brown or purple color (it is also possible to develop laryngeal edema);
- mechanical asphyxia;
- burn shock;
- motor excitement, convulsions, parkinsonism;
- hemorrhagic colitis;
- hepatopathy;
- nephropathy;
- methemoglobinemia with shortness of breath and severe cyanosis (in patients with low acidity of gastric juice).
Recommended treatment:
- ascorbic acid (intravenously 30 ml of 5% solution);
- methylthioninium chloride (50 ml of a 1% solution);
- pyridoxine (intramuscularly 3 ml of 5% solution);
- cyanocobalamin (up to 1 mg).
The lethal dose of the drug for children is approximately 3 g, for adults - from 0.3 to 0.5 g / kg.
special instructions
When applied externally, even a small concentration of potassium permanganate solution can stain the skin brown.
Ingestion of a highly concentrated solution of potassium permanganate causes intoxication of the body, the symptoms and consequences of which can be: nausea and vomiting with a brownish admixture, edema, brown color and corrosion of the oral mucosa, damage to the liver and kidneys, gastrointestinal bleeding, and suppression of the heart.
Potassium permanganate should not be used as a drug for abortion, since such a procedure is fraught with great danger to the health and life of the pregnant woman. When injected into the vagina, a highly concentrated solution causes deep burns, perforation of the vaginal wall, severe bleeding, peritonitis, vascular collapse.
Application during pregnancy and lactation
According to the instructions, potassium permanganate during these periods is used only in cases where the benefit to the woman outweighs the possible harm to the child.
Drug interactions
Clinically significant drug interactions of the solution have not been established.
Analogs
Potassium permanganate analogs are: Ammonia + glycerol + ethanol, Aseptolin, Anmarin, Baktoderm, Vitaon, Dermatolo-tar liniment, Dioxizol, ZelenKa, Kaleflon, Katapol, Katacel, Naftalan ointment, Ethyl alcohol mud, Protolamb, Perekmiad Formagel, Elekasol, Etol 96%, Zinc-salicylic paste, Chaga.
Terms and conditions of storage
Store in a dry place out of reach of children.
The shelf life is 5 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about potassium permanganate
Reviews of Potassium permanganate indicate that this antiseptic is very popular (including when caring for newborns). Users point to the effectiveness of the drug in the treatment of skin diseases, tonsillitis, poisoning, cystitis, etc.
Some women use a mild solution of potassium permanganate to combat unwanted hair, which becomes thinner and less visible with regular use.
Price for Potassium permanganate in pharmacies
The price of Potassium permanganate, depending on the form of release and the volume of the package, is 11-165 rubles.
Potassium permanganate: prices in online pharmacies
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Drug name Price Pharmacy |
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Potassium permanganate powder for solution preparation for local and external use 3 g 1 pc. RUB 40 Buy |
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Potassium permanganate powder for solution preparation for local and external use 3 g 1 pc. RUB 49 Buy |
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Potassium permanganate powder for solution preparation for local and external use 5 g 1 pc. RUB 61 Buy |
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Potassium permanganate powder for preparation of a solution for local and external use 15 g 1 pc. 172 r Buy |
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
