Rennie's drug for heartburn
The content of the article:
- Description of the drug
- Composition
- Excretion routes
- Indications for appointment
- Contraindications for use
- How to take Rennie for heartburn
- Side effects
- Overdose
- Drug interactions
- Features of use under certain conditions
- Price
- Reviews after a course of therapy
-
Some analogues
- Almagel
- Renikzon
- Maalox
- Video
Rennie for heartburn is used as the main remedy for this symptom. The drug is in second place after the use of drugs from the group of proton pump blockers (one of the most popular representatives is Omeprazole).
Tablets belong to the group of antacids. Features of this group of drugs:
- causes the neutralization of hydrochloric acid in the stomach;
- forms a protective film on the surface of the gastric mucosa (effective for ulcerative lesions of the gastrointestinal tract);
- applies to all age groups;
- allowed during lactation and pregnancy.
Rennie's drug is a popular remedy for heartburn
Description of the drug
Rennie is one of the first means of relieving an unpleasant burning sensation in the epigastric region. The clinical effect occurs in 3-5 minutes.
The instructions for use describe the general characteristics and indications, therefore, the appointment is permissible only after consultation with a specialist (gastroenterologist) and the establishment of the main diagnosis.
The effect of the treatment occurs immediately after the first application. The drug allows you to quickly stop the main symptom (burning sensation in the epigastrium), but serve only as a means of symptomatic therapy, that is, it does not eliminate the cause of the pathology.
Composition
The tablets contain two main active ingredients:
- calcium carbonate - 680 mg;
- magnesium carbonate basic - 80 mg.
There is also a list of excipients that are not related to the action of the drug. The number of excipients determines the variety of analogs and generics that copy the main drug (by changing the ratio of the main and excipients, a new drug with similar properties is obtained).
Externally, Rennie is represented by white, square tablets with a concave core and the trade name printed on one side.
Available in packs of 6 or 12 tablets.
Excretion routes
It is excreted mainly through the kidneys (up to 80%). In case of impaired renal function (renal failure), the concentration of active substances in the blood increases.
Less than 20% is excreted in the feces as insoluble compounds. There is no elimination half-life since this drug is not absorbed.
Indications for appointment
There is a list of diseases for which there are indications for the appointment of Rennie or its analogues from the group of antacids:
- Diseases of the digestive system (heartburn, ulcers, gastritis, gastroesophageal reflux disease). The main action is associated with the elimination of pain and the normalization of life.
- Dyspepsia not associated with nutritional errors.
- Dyspepsia during pregnancy.
The course of therapy is prescribed taking into account the duration and intensity of heartburn.
Contraindications for use
Since the drug has a local effect, the list of contraindications is not numerous:
- renal failure (severe);
- increased calcium content due to endocrine diseases (dysfunction of the parathyroid glands);
- intolerance or hypersensitivity to certain elements of the drug.
It is permissible to include a drug in the treatment regimen only if these conditions are absent, that is, after a thorough diagnosis.
How to take Rennie for heartburn
The drug is equally effective in helping adults and children. The instruction assumes use in children over 12 years old, since no clinical trials have been conducted on the use of children in younger age groups.
Take 1 tablet if you experience pain or burning sensation. The daily dose should not exceed 12 tablets.
The tablet is taken either by thorough chewing, or by keeping the tablet in the mouth for a long time and slowly dissolving it. After taking one pill, the next one can be taken no earlier than 2 hours later.
Side effects
Side effects when taking antacids are extremely rare. Among them are:
- allergic rash (different localization, polymorphism, rapid onset);
- Quincke's edema (an extreme variant of an allergic reaction is akin to anaphylactic shock);
- rarely nausea, vomiting, bowel upset occurs;
- rarely muscle weakness and weakness;
- rarely on the part of the kidneys - azotemia.
The incidence of side effects is less than 0.001% (approximately 1 case per 10,000 people).
Overdose
With a single dose of more than 16 tablets, a pronounced impairment of renal function occurs. The amount of calcium and magnesium in the blood increases significantly, which leads to a shift in pH to the alkaline side (alkalosis).
Common manifestations in this case:
- nausea and vomiting;
- muscle weakness;
- dizziness and drowsiness.
Shows an immediate appeal to the emergency room or calling an ambulance.
Drug interactions
Since the drug forms a film on the surface of the stomach, the absorption of other medicinal substances is impaired. Their use is shown no earlier than 2 hours after taking Rennie.
Enhances the action of barbiturates and iron preparations.
Prolongs the action of anticholinergic drugs.
When taken simultaneously with thiazide diuretics, constant monitoring of renal function is necessary (biochemical blood test - urea and creatinine).
Features of use under certain conditions
Caution is required for the following groups:
| Group | Explanation |
| Patients with impaired renal function | Shown constant control over the biochemical blood test (level of magnesium, calcium) |
| Patients with gallstone disease | The risk of additional or growth of existing stones increases. |
| Patients with type I diabetes | One of the auxiliary components of the drug is sucrose (sugar control is required). |
Does not affect drivers, i.e. does not affect concentration.
Price
The price will vary slightly depending on the region and the city, on average 200-300 Russian rubles.
Reviews after a course of therapy
Patient reviews are in most cases positive (up to 80%). Some people who took the drug did not notice a pronounced clinical effect (10-15%). Less than 5% of those taking Rennie reported worsening after use.
Some analogues
In a single group of analogs, drugs are united by the similarity of action and chemical composition. Differences are usually present in the change in several components of the drug (not a fundamental substitute) and in the price scale.
Almagel
The composition includes the following components:
- aluminum hydroxide - 340 mg;
- magnesium hydroxide - 395 mg;
- simethicone - 36 mg;
- Excipients.
Available in suspension form.
Features:
- Not recommended for children, as it leads to pronounced changes in hemoglobin levels.
- Not recommended for severe surgical pathologies (necrotizing ulcerative colitis, colostomy or ileostomy).
- Not prescribed during pregnancy and lactation, as there are not enough clinical trials at the moment regarding these populations.
- Not recommended for Alzheimer's.
Take 5-10 ml (1-2 scoops) 10 minutes before meals 3-4 times a day. The course of therapy is 7 days. In general, reviews of the drug are positive (well tolerated by more than 70% of the population and has minor adverse reactions).
Renikzon
Includes:
- calcium carbonate - 680 mg;
- magnesium carbonate basic - 80 mg;
- Excipients.
Available in tablet form. The indications are identical to other drugs from the antacid group.
Features:
- Do not use for violations of carbohydrate metabolism (intolerance to fructose, sucrose).
- Do not use in children under 7 years of age.
The dosage regimen is identical to Rennie's. The drug is 80% similar to Rennie. The difference lies in the replacement of one of the main active ingredients.
Maalox
Includes:
- magnesium hydroxide 400.0 mg;
- aluminum hydroxide 400.0 mg;
- Excipients.
Available in tablet form.
The main distinguishing features:
- In addition to neutralizing hydrochloric acid, it additionally has an adsorbing and enveloping effect.
- Do not use in persons under 15 years of age.
- Not recommended during pregnancy and lactation due to lack of clinical trials.
- Has multiple cross-reactions with other drugs.
Apply 1-2 tablets 3 times a day. The time interval between doses is 2 hours.
Side effects are rare and nonspecific.
Video
We offer for viewing a video on the topic of the article.
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
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