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Trekresil: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. In case of impaired renal function
- 12. For violations of liver function
- 13. Use in the elderly
- 14. Drug interactions
- 15. Analogs
- 16. Terms and conditions of storage
- 17. Terms of dispensing from pharmacies
- 18. Reviews
- 19. Price in pharmacies
Latin name: Trekresil
ATX code: A13A
Active ingredient: oxyethylammonium methylphenoxy acetate
Producer: Aromasintez, LLC (Russia)
Description and photo update: 2020-18-02
Trekresil is an adaptogenic and restorative drug.
Release form and composition
The drug is produced in the form of tablets: round, flat-cylindrical, white or white with a yellow tint, with a risk and a chamfer (10 pieces in a blister strip, in a cardboard box of 1, 2, 3 or 5 packages and instructions for using Trekresil).
1 tablet contains:
- active substance: oxyethylammonium methylphenoxyacetate - 200 mg;
- additional components: lactose monohydrate, calcium stearate, potato starch.
Pharmacological properties
Pharmacodynamics
Trekresil belongs to the group of adaptogenic drugs. It stimulates the production of α- and γ-interferons, which determines the spectrum of its biological action - adaptogenic, immunostimulating. Oxyethylammonium methylphenoxyacetate, as a result of activation of humoral and cellular immunity, affects the immune status of the body, and also provides an increase in the phagocytic activity of macrophages. Currently, the exact mechanism of action of the drug has not been established. The above effects of the drug help to increase endurance in case of excessive physical and mental stress, weaken the effect of various toxins, increase the body's resistance to hypoxia, high and low temperatures and other environmental factors that have an adverse effect.
Pharmacokinetics
It has been established that the active substance Trekresil has a high bioavailability, is actively metabolized in the liver, and is eliminated by the kidneys, mainly in the form of glucuronides. With prolonged use, it does not accumulate in the body.
Pharmacokinetic parameters of the active component of the drug in elderly patients, adolescents 12–18 years old, patients with hepatic and renal insufficiency do not change significantly.
Indications for use
Trekresil is recommended for use in combination therapy for the following conditions / diseases:
- acute respiratory viral infections (ARVI) (prevention and treatment);
- period of significant intellectual and physical exertion;
- various stressful influences (hypothermia, overheating, hypoxia), unfavorable environmental influences (drops in atmospheric pressure, abrupt change in climatic conditions) - in order to enhance the stability and adaptation of the organism.
Contraindications
Absolute:
- age up to 12 years;
- pregnancy and lactation;
- impaired absorption of glucose and galactose, lactase deficiency, hereditary lactose intolerance;
- hypersensitivity to any component of the product.
It is required to use Trekresil with extreme caution in patients with diabetes mellitus.
Trekresil, instructions for use: method and dosage
Trekresil tablets are taken orally.
Recommended dosage regimen (as part of complex therapy) for adults and children over 12 years old:
- SARS (for prevention): once a day, 200 mg (1 tablet) after meals; course - 14 days, total dose - 2800 mg (14 tablets);
- ARVI (therapy), a period of increased mental and physical stress, various stressful influences and unfavorable environmental factors (for adaptation and increasing resistance): on the first day - 3 times a day, 200 mg, in the next 7 days - 1 time a day, 200 mg; course - 8 days, total dose - 2000 mg (10 tablets).
If, 3 days after the start of the course of treatment, there is no improvement in the state of health and a decrease in the severity of the symptoms of the above conditions, you should consult your doctor.
Side effects
While taking the drug, in rare cases, there may be the appearance of allergic reactions, such as Quincke's edema, hypersensitivity reactions, anaphylaxis, anaphylactic shock. If any of these side effects worsen or any other adverse event occurs, you should consult a specialist.
Overdose
The onset of symptoms of intoxication due to drug overdose was not observed. If an overdose is suspected, symptomatic treatment is recommended.
special instructions
In the case of ARVI, it is imperative to consult a doctor if the following symptoms occur:
- body temperature above 39 ° C;
- shortness of breath, severe pain, impaired consciousness and convulsions against the background of an increase in temperature;
- body temperature above 38.5 ° C, observed for 3 days or more and accompanied by symptoms of acute respiratory disease (ARI);
- temperature above 37.5 ° C observed for 14 days or more.
Do not use the drug in doses exceeding the recommended ones.
Influence on the ability to drive vehicles and complex mechanisms
Taking Trekresil tablets does not affect the ability to drive or perform any potentially hazardous activities.
Application during pregnancy and lactation
Therapy with the drug in pregnant and breastfeeding women is contraindicated due to the lack of data on the safety and efficacy of its use in patients of this category.
Pediatric use
The drug is contraindicated in children under 12 years of age, since the safety profile of Trekresil in patients of this age category has not been studied.
With impaired renal function
Patients with functional impairment of the kidneys do not need to adjust the dosage regimen.
For violations of liver function
Patients with functional disorders of the liver do not need to change the dosage regimen of Trekresil.
Use in the elderly
Elderly people do not need to take any special precautions when using Trekresil.
Drug interactions
No undesirable interaction of oxyethylammonium methylphenoxyacetate with other drugs / preparations has been recorded.
Analogs
Trekresil's analogs are Trekresolid, Trekrezan, Metaprot, Propolis tincture, etc.
Terms and conditions of storage
Store in a place out of the reach of children, protected from light, at a temperature not exceeding 25 ° C.
Shelf life is 2 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Trekresil
Reviews about Trekresil on specialized sites are very rare and are usually positive. Patients who took the drug note its effectiveness in the treatment and prevention of colds and ARVI. Already on the third day of the course, the drug reduces the severity of the symptoms of these diseases and improves overall well-being. Also, an adaptogenic agent helps to strengthen immunity, enhance the efficiency and endurance of the body, not inferior in performance to its expensive foreign counterparts.
The disadvantages of the drug include the possible development of allergic reactions during the period of administration.
Price for Trekresil in pharmacies
There is no reliable information on the price of Trekresil, since the drug is currently not sold in pharmacies. The cost of an analogue of the drug, Trekrezan, in the form of tablets can be 310-370 rubles. for 10 pcs. packaged.
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!