Olyfrin - Instructions For Using The Spray, Analogs, Reviews, Price

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Olyfrin - Instructions For Using The Spray, Analogs, Reviews, Price
Olyfrin - Instructions For Using The Spray, Analogs, Reviews, Price

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Olyfrin: instructions for use and reviews

  1. 1. Release form and composition
  2. 2. Pharmacological properties
  3. 3. Indications for use
  4. 4. Contraindications
  5. 5. Method of application and dosage
  6. 6. Side effects
  7. 7. Overdose
  8. 8. Special instructions
  1. 9. Application during pregnancy and lactation
  2. 10. Use in childhood
  3. 11. Drug interactions
  4. 12. Analogs
  5. 13. Terms and conditions of storage
  6. 14. Terms of dispensing from pharmacies
  7. 15. Reviews
  8. 16. Price in pharmacies

Latin name: Olifrin

Active ingredient: hyaluronic acid, glycerol (glycerolum), lemon oil expressed, vitamin E (vitamin E) [racemic α-tocopheryl acetate (all-rac-α-Tocopheryl acetate)]

Manufacturer: Solopharm (Russia)

Description and photo update: 28.11.2018

Prices in pharmacies: from 192 rubles.


Means for the nasal mucosa Olifrin
Means for the nasal mucosa Olifrin

Olyphrin is used in otorhinolaryngology to care for the nasal cavity.

Release form and composition

Olifrin is a remedy for the nasal mucosa: an opaque, slightly oily liquid of white-yellow color, with a citrus aroma (15 ml each in plastic bottles with a nozzle, in a cardboard box, 1 bottle and instructions for the use of Olifrin).

Composition for 1 ml of the product:

  • active ingredients: anhydrous glycerol - 62.5 mg, sodium hyaluronate - 1.9 mg, essential lemon oil - 0.6 mg, racemic α-tocopherol acetate (vitamin E) - 0.1 mg;
  • excipients: macrogol glyceryl hydroxystearate 40, polysorbate 80 (tween 80), sodium benzoate, water for injection.

Pharmacological properties


Olyphrin has a moisturizing and anti-inflammatory effect, eliminates the symptoms of dryness of the nasal mucosa (itching, irritation, burning), promotes its regeneration, and creates a barrier that protects against adverse factors.

Action of active ingredients:

  • hyaluronic acid: a natural polymer present in the human body has lubricating and moisturizing properties and the necessary viscosity to create a protective film in the nasal cavity with a high ability to retain moisture, which provides long-term uniform hydration and protects the nasal mucosa from adverse environmental influences;
  • glycerol: is a natural hydratant with high hygroscopic (intensely moisturizes, protects against dehydration) and lubricating properties; has a softening effect; activates metabolism, improving regeneration; has an antipruritic effect;
  • essential lemon oil: helps to strengthen the walls of blood vessels, has antiseptic efficacy; thanks to the refreshing lemon scent, tones up and noticeably improves mood;
  • Vitamin E (racemic α-tocopherol acetate): anti-inflammatory due to its high antioxidant activity.

Indications for use

  • creating a protective barrier in the nasal cavity and moisturizing the nasal mucosa;
  • removal of excess secretions, softening and removal of crusts formed in the nasal cavity;
  • elimination of dryness symptoms (itching, irritation, burning) of the nasal mucosa caused by negative environmental influences, exposure to dry air (heating, air conditioning) or postoperative healing;
  • relief of increased bleeding resulting from thinning and dryness of the mucous membrane;
  • acceleration of the regeneration of the nasal mucosa after surgery;
  • long-term use of local vasoconstrictor drugs, which caused pathological changes in the nasal mucosa.


  • absolute obstruction of the nasal passages;
  • children under 3 years old;
  • individual hypersensitivity to the components of Olifrin.

Olifrin, instructions for use: method and dosage

Spray Olifrin is used intranasally.

It is recommended to make 1-2 injections into each nostril from 1 to 3 times a day as needed.

If more frequent use of the agent is required, the duration and frequency of its use are not limited.

Side effects

Possible side effects of Olifrin have not been identified.


Information about cases of drug overdose has not yet been reported.

special instructions

The mucous membrane of the nasal cavity is a protective barrier of the body and is daily exposed to the negative influence of various factors that can lead to its irritation and increase dryness.

Factors that contribute to increased dryness of the nasal mucosa should be considered:

  • external: long-term stay in places with cold / dry air, unfavorable ecology (smog, pollution), conditioned dry air;
  • internal: hypersensitivity reactions, side effects of rhinitis drugs, hormonal disorders during pregnancy or during the menopausal period.

Olyphrin is intended for use at home and in medical institutions.

The spray is a personal product. At home, carrying out procedures with a medical device does not require special training / skills.

Before using Olifrin, you must carefully inspect the packaging, and if it is damaged, the product cannot be used.

When disposed of, the drug belongs to class A (epidemiologically safe waste) and must be processed as household waste.

Influence on the ability to drive vehicles and complex mechanisms

Olyfrin does not apply to drugs that can affect the psychomotor state of a person.

Application during pregnancy and lactation

Olyfrin spray is approved for use by pregnant and breastfeeding women.

Pediatric use

The drug is contraindicated for use in children under 3 years of age.

Drug interactions

A special-purpose medical device Olyphrin is allowed to be used with all drugs for intranasal use and physiotherapy procedures.


The analogues of Olyphrin are: Aqua Maris, Aqua More, Doctor Theiss sea water, Quix, Morenazal, Marimer, Nazol Aqua, Sialor Aqua, Otrivin More, Fluimarin, Physiomer, Humer, Chistonos, etc.

Terms and conditions of storage

Keep out of the reach of children.

Store at a temperature of + 5 … + 25 ° С.

The shelf life is 3 years.

Terms of dispensing from pharmacies

Available without a prescription.

Reviews about Olifrin

Most patients leave extremely positive reviews about Olifrin, since the spray perfectly moisturizes the nasal mucosa, helps with bleeding, dryness and is easy to use. In addition, almost all users love the product's pleasant lemon scent. The lack of oily (greasy feeling) is also noted. After application, there is a rapid improvement in the condition.

As disadvantages, they point to a tingling in the nose at the beginning of using the spray. Most consider the cost of the drug affordable.

Olyfrin price in pharmacies

The approximate price of Olifrin (for 15 ml of a moisturizer in the form of a nasal spray in a bottle) is 192 rubles.

Olyfrin: prices in online pharmacies

Drug name



Olyphrin nasal spray 15 ml 1 pc.

192 RUB


Olyfrin medium for nasal mucosa spray bottle 15ml

227 r


Maria Kulkes
Maria Kulkes

Maria Kulkes Medical journalist About the author

Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".

Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!

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