Contractubex
Kontraktubex: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. Analogs
- 12. Terms and conditions of storage
- 13. Terms of dispensing from pharmacies
- 14. Reviews
- 15. Price in pharmacies
Latin name: Contractubex
ATX code: D03AX
Active ingredient: Allantoin (Allantoin) + Heparin sodium (Heparin sodium) + Onion bulb extract (Allii cepae squamae extract)
Manufacturer: Merz Pharma GmbH & Co. KGaA (Merz Pharma, GmbH & Co, KGaA) (Germany)
Description and photo update: 2019-20-08
Prices in pharmacies: from 400 rubles.
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Contractubex is a combined external preparation with proteolytic activity, used for resorption of keloid scars.
Release form and composition
Kontraktubex is produced in the form of a gel for external use: light brown, matte, with a characteristic odor (in aluminum tubes of 20 or 50 g, 1 tube in a cardboard box).
The composition of 1 g of gel contains active ingredients:
- Onions - 0.1 g (in the form of a liquid extract);
- Allantoin - 0.01 g;
- Heparin sodium - 50 IU (international units).
Auxiliary components: methyl parahydroxybenzoate, sorbic acid, polyethylene glycol 200 (macrogol 200), netrol F (xanthan gum), flavored oil (chrome 2700), purified water.
Pharmacological properties
Pharmacodynamics
Kontraktubex is characterized by keratolytic (due to allantoin), antithrombotic (due to sodium heparin), anti-inflammatory and fibrinolytic (due to onion extract) action.
The drug enhances cell regeneration without increasing their number (hyperplasia) and inhibits the proliferation of keloid fibroblasts.
Pharmacokinetics
Studies have shown that sodium heparin in therapeutic concentrations for 4 hours penetrates the connective tissue of the dermal layer of the skin. Its combination with allantoin and onion extract allows for transepidermal heparinization (sufficient penetration depth).
When using Contractubex, there is no systemic absorption.
Indications for use
- Keloid and hypertrophic scars that appeared after amputation, trauma, burns, surgical interventions (treatment and prevention);
- Atrophic scars, which appeared, in particular, after furunculosis or acne;
- Contractures (ankylosis) of the joints;
- Dupuytren's Contract;
- Tendon contractures associated with trauma;
- Stretch marks that occur after pregnancy.
The drug can be used in children.
Contraindications
According to the instructions, Kontraktubex is contraindicated for use in the presence of hypersensitivity to the components of the drug.
The efficacy and safety of using the gel by lactating and pregnant women has not been studied.
Instructions for the use of Kontraktubex: method and dosage
Gel Kontraktubex is used externally.
The drug is used 2-3 times a day, gently rubbing it into the scar tissue. Consumption of Kontraktubex for 1 application averages 0.5 cm of gel on a surface of about 20-25 cm².
For dense old scars, an occlusive dressing with a gel should be applied at night.
To prevent the appearance of scars, the agent is used in the phase after the epithelialization of the wound (the gel should not be applied to granulation).
The average course of therapy is:
- Fresh scars - 1 month;
- Dense old scars - from 3 to 6 months;
- Dupuytren's contract - 1 year.
Side effects
In rare cases, local skin reactions may occur when using Contractubex.
Overdose
Overdose cases have not been registered.
special instructions
To enhance the effect, the gel is recommended to be applied to previously steamed skin.
The simultaneous use of Kontraktubex in combination with physiotherapy procedures is possible.
When treating fresh scars, avoid ultraviolet radiation, intense massage and exposure to cold.
Influence on the ability to drive vehicles and complex mechanisms
The drug does not affect the ability to drive vehicles or perform complex types of work that require increased concentration and quick psychomotor reactions.
Application during pregnancy and lactation
Studies on the efficacy and safety of the use of Kontraktubex during pregnancy and breastfeeding (lactation) have not been conducted.
Pediatric use
It is allowed to use the gel to treat children.
Drug interactions
There are no data on the interaction of Kontraktubex with other drugs.
Analogs
Analogs of Kontraktubex are: Algofin, Aekol, Wundehil, Vinilin, Dermatiks, Mederma.
Terms and conditions of storage
Keep out of reach of children at temperatures up to 25 ° C.
Shelf life is 4 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Contractubex
Reviews about Kontraktubeks are quite diverse. Some patients find the gel ineffective, while many patients claim that the drug helped them get rid of unpleasant skin blemishes.
If used regularly for a long time, the gel helps to eliminate residual spots after chickenpox during conservative sanitation, since they are not scars, but hyperpigmented inflamed skin areas. Thanks to its active components, inflammation is minimized and local blood circulation is improved.
A number of dermatologists are skeptical about the effectiveness of this drug, which, in their opinion, has no evidence base. As a cream for acne, the gel can be recommended for long-term use in adolescents, however, when applied, it is almost impossible to completely eliminate scar tissue, according to experts. Although Contractubex has antiproliferative and other beneficial properties, scars can only be removed by surgery or laser. At the same time, even when applying the gel to the spots after acne, it is impossible to prove whether the drug really helped or the skin defects (with a small pustule that the patient did not open) disappeared on their own.
Reviews of the gel as a good tool that helps to eliminate postpartum stretch marks or scars after a cesarean section are also questioned by qualified specialists, since stretch marks are dense connective tissue that forms as a result of the rapid increase in a pregnant woman's abdomen in size. It is considered doubtful that such effects can be eliminated only with the help of a gel.
Also, sometimes Kontraktubex is used for synechiae, but if the disease is accompanied by a violation of the outflow of urine or infection of the labia minora, then it is advisable to use hormonal agents based on estrogen. This drug is not in this category and may not be helpful.
Price for Contractubex in pharmacies
The approximate price for Kontraktubex is about 626‒674 rubles. for a tube of 20 g or 918‒1022 rubles. per tube 50 g.
Kontraktubex: prices in online pharmacies
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Drug name Price Pharmacy |
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Contractubex gel for external use 20 g 1 pc. RUB 400 Buy |
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Contractubex gel 20g 505 RUB Buy |
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Contractubex Anti-Red Gel 20 g 1 pc. RUB 518 Buy |
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Contractubex gel for external use 50 g 1 pc. 754 RUB Buy |
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Kontraktubex plaster long-acting plaster 21 pcs. 1126 RUB Buy |
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
