Tick-E-Vac - Instructions For Use Of The Vaccine, Vaccination For Children, Price

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Tick-E-Vac - Instructions For Use Of The Vaccine, Vaccination For Children, Price
Tick-E-Vac - Instructions For Use Of The Vaccine, Vaccination For Children, Price

Video: Tick-E-Vac - Instructions For Use Of The Vaccine, Vaccination For Children, Price

Video: Tick-E-Vac - Instructions For Use Of The Vaccine, Vaccination For Children, Price
Video: Should My Child Get Vaccinated For COVID-19? Common Vaccination Questions Parents Have 2023, March


Tick-E-Vak: instructions for use and reviews

  1. 1. Release form and composition
  2. 2. Pharmacological properties
  3. 3. Indications for use
  4. 4. Contraindications
  5. 5. Method of application and dosage
  6. 6. Side effects
  7. 7. Overdose
  8. 8. Special instructions
  1. 9. Application during pregnancy and lactation
  2. 10. Use in childhood
  3. 11. Drug interactions
  4. 12. Analogs
  5. 13. Terms and conditions of storage
  6. 14. Terms of dispensing from pharmacies
  7. 15. Reviews
  8. 16. Price in pharmacies

Latin name: Tick-E-Vac

ATX code: J07BA01

Active ingredient: inactivated antigen of tick-borne encephalitis virus - titer not less than 1: 128 (Inactivated antigen de tick-genuisset encephalitis virus - titer non minus quam 1: 128)

Manufacturer: Federal State Unitary Enterprise for the Production of Bacterial and Viral Preparations of the Institute of Poliomyelitis and Viral Encephalitis. M. P. Chumakova of the Russian Academy of Medical Sciences (Russia)

Description and photo update: 2019-12-07

Prices in pharmacies: from 3620 rubles.


Suspension for intramuscular (i / m) administration Mites-E-Vac
Suspension for intramuscular (i / m) administration Mites-E-Vac

Tick-E-Vac is a cultured purified concentrated inactivated sorbed vaccine for the prevention of tick-borne encephalitis.

Release form and composition

The drug is available in the form of a suspension for intramuscular (i / m) administration: a liquid with a homogeneous structure, white, without foreign inclusions [0.5 ml each (dose for persons aged 16 and older) or 0.25 ml (dose for children from 1 to 16 years old) in ampoules, in a cardboard box 10 ampoules complete with an ampoule knife or without it and instructions for use Klesh-E-Vac].

One vaccination dose contains:

  • active ingredient: inactivated TBE virus antigen (tick-borne encephalitis) - titer not less than 1: 128;
  • excipients: human albumin (10 or 20% solution for infusion - albumin, sodium caprylate, sodium chloride), aluminum hydroxide, sucrose, salts of the buffer system - trometamol and sodium chloride.

The suspension does not contain antibiotics, formaldehyde and preservatives.

Pharmacological properties


Tick-E-Vac is a concentrated vaccine for the prevention of tick-borne encephalitis. It is a purified suspension of the formalin-inactivated TBE virus strain "Sof'in", which is obtained by reproduction in a primary cell culture of chicken embryos and is sorbed on aluminum hydroxide. The immunobiological property of the vaccine is to stimulate the production of cellular and humoral immunity to the TBE virus. After a course of vaccination, consisting of two injections of Mite-E-Vac, the presence of neutralizing antibodies is detected in 90% of those vaccinated.

Indications for use

The use of Mite-E-Vac is indicated for the specific prevention of TBE in the population (children from 1 to 16 years old at a dose of 0.25 ml and persons from 16 years of age and older at a dose of 0.5 ml), which permanently or temporarily lives on enzootic on FE territories.

The temporarily residing contingent includes persons visiting these territories for the purpose of working in summer cottages and garden plots, recreation, tourism and performing certain types of activities (fishing, procurement, expeditionary, geological, prospecting, deratization and disinsection works, hydro reclamation, construction, excavation and relocation soil, work in agriculture, logging, forest clearing and improvement, recreation areas and recreation of the population).

Persons working with TBE virus-containing materials, as well as donors, to obtain specific immunoglobulin, are subject to immunization.



  • infectious and non-infectious diseases, the stage of exacerbation of chronic pathologies, including a period of at least 30 days after recovery (remission);
  • a history of severe allergic reactions;
  • autoimmune diseases;
  • bronchial asthma;
  • the appearance of a complication or a pronounced reaction (an increase in body temperature above 40 ° C, edema and / or hyperemia in a diameter of more than 8 cm at the site of vaccine administration) during the previous immunization;
  • less than two weeks after delivery;
  • age up to 1 year;
  • established allergy to Mite-E-Vac components.

In addition, when vaccinating donors, it is necessary to take into account contraindications to blood donation.

With great caution and only if there is strong evidence of the risk of possible infection with the TBE virus, a decision should be made about vaccination during pregnancy.

Tick-E-Vak, instructions for use: method and dosage

Tick-E-Vak should not be used intravenously!

The vaccine is administered by intramuscular injection into the deltoid muscle of the shoulder.

Vaccinations are carried out, strictly observing the rules of asepsis and antiseptics, in a specially equipped room, equipped with anti-shock and anti-allergic therapy.

Before opening the ampoule, it is necessary to visually assess its contents for suitability. In the event of a violation of integrity, labeling, the presence of foreign inclusions or an expired shelf life, the drug should be disposed of.

If, after shaking the ampoule, the suspension acquires a homogeneous structure, without any inclusions, then the ampoule can be opened and inoculated.

Due to the existing risk of developing allergic reactions of an immediate type after vaccination, the patient should be under medical supervision for 0.5 hour.

To exclude the presence of contraindications, on the day of the Mite-E-Vac vaccination, the doctor (paramedic) must conduct an examination, measure the patient's body temperature and interview for possible health complaints.

Scheme of preventive vaccination:

  • routine vaccination: 1 inoculation dose for persons aged 16 and over is 0.5 ml, 1 inoculation dose of Mite-E-Vac for children from 1 to 16 years old - 0.25 ml. Primary vaccination consists of two doses, which are administered in turn with an interval of 1-7 months, the most optimal period between the first and second vaccinations is 5-7 months (autumn - spring). Vaccinations can be carried out throughout the year, including the epidemic season. The TBE outbreak during the epidemiological season can be visited no earlier than 1/2 month after the second dose of the vaccine;
  • emergency vaccination (in the presence of epidemic indications): 0.5 ml for persons from 16 years of age and older and 0.25 ml for children from 1 year to 16 years, twice with an interval of 1/2 month. A visit to the TBE focus during the epidemiological season is allowed only 1/2 month after the second vaccination.

12 months after the completion of the primary course of routine or emergency preventive vaccination, it is necessary to carry out the first revaccination. It consists of a single injection of Mites-E-Vac at a dose of 0.5 ml - for persons aged 16 and over and at a dose of 0.25 ml - for children from 1 to 16 years old.

Subsequent revaccinations are carried out regularly at intervals of 36 months by a single dose, corresponding to the person's age.

The course of vaccination in donors consists of two doses of 0.5 ml, which are administered at intervals of 5–7 months or three doses of 0.5 ml at intervals of 3-5 weeks between vaccinations. The first scheme is considered the most optimal, providing the best immunization. Revaccination is performed by administering a single dose of 0.5 ml every 6–12 months. The first blood sampling from donors is indicated not earlier than 1 / 2-1 month after the vaccination course.

Side effects

After vaccination (within the first 48 hours), local reactions may occur in people of all ages. Often their manifestation is redness, soreness at the injection site and / or swelling, very rarely - the formation of an infiltrate, a slight increase in regional lymph nodes. Local reactions usually last no more than 72 hours.

In some cases, after the administration of the Mite-E-Vac vaccine, general reactions may develop: during the first 48 hours - in persons aged 16 and older, 72 hours - in children from 1 year to 16 years. Children and adults are at risk of developing the following systemic adverse events:

  • very often (> 1/10): an increase in body temperature up to 37.5 ° C in children aged 1-16 years;
  • often (≥ 1/100 to <1/10): general malaise, nausea, headache, fever up to 37.5 ° C in persons aged 16 years and older or up to 38.5 ° C in children from 1 years up to 16 years;
  • infrequently (≥ 1/1000 to <1/100): an increase in body temperature from 37.5 to 38.5 ° C in persons aged 16 years and older;
  • rarely (≥ 1/10 000 to <1/1000): an increase in body temperature above 38.5 ° C.

The duration of common reactions is usually no more than 48 hours in adults and 72 hours in children aged 1 to 16 years. Usually local and general reactions develop after the first dose of the Mites-E-Vac vaccine.

There are isolated cases of immediate allergic reactions.


Overdose symptoms have not been established.

special instructions

The Mites-E-Vac vaccination carried out must be registered in the established registration form, which indicates the name of the drug, batch number, manufacturer, date, dose and reaction to vaccination.

Influence on the ability to drive vehicles and complex mechanisms

In cases where general reactions to the introduction of Mite-E-Vac are pronounced (headache, high body temperature), patients should temporarily stop driving vehicles and complex mechanisms.

Application during pregnancy and lactation

The safety of using Tick-E-Vac in pregnant and lactating women has not been established. Therefore, vaccination during gestation can be prescribed only if there is information about the risk of possible infection with the TBE virus.

The use of the vaccine during lactation is indicated 2 weeks after delivery.

Pediatric use

The use of Mites-E-Vac in children under the age of 1 year is contraindicated.

Drug interactions

Simultaneous prophylactic vaccination with rabies vaccine is contraindicated. On one day, immunization against TBE and the introduction of other inactivated vaccines of the National calendar of preventive vaccinations and the calendar of preventive vaccinations for epidemic indications are allowed. Vaccination against TBE can be carried out no earlier than 30 days after the introduction of a vaccine against another infectious disease.


Analogs of Tick-E-Vac are: Cultural purified concentrated inactivated dry vaccine of tick-borne encephalitis, FSME-Immun Inject, FSME-Immun Junior, EnceVir, EnceVir Neo for children, Encepur for adults, Encepur for children.

Terms and conditions of storage

Keep out of the reach of children.

Store at 2–8 ° C, during transportation within no more than 24 hours - 9–20 ° C, do not freeze.

Shelf life is 2 years.

Terms of dispensing from pharmacies

For hospitals.

Reviews of Tick-E-Vake

Reviews of Tick-E-Vake are positive. Persons visiting or living in areas endemic for the TBE virus, note the high immunobiological properties of the vaccine, good tolerance.

Price for Tick-E-Vac in pharmacies

The price for Klesh-E-Vac for a package containing 10 ampoules of suspension in a dose of 0.25 ml can be 5180-5298 rubles, for a dose of 0.5 ml - 5150-5980 rubles.

Klesh-E-Vac: prices in online pharmacies

Drug name



Tick-E-Vac Tick-borne encephalitis vaccine suspension for intramuscular administration 0.5 ml 10 pcs.

3620 RUB


Anna Kozlova
Anna Kozlova

Anna Kozlova Medical journalist About the author

Education: Rostov State Medical University, specialty "General Medicine".

Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!

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