Glycerin suppositories
Glycerin suppositories: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. Drug interactions
- 12. Analogs
- 13. Terms and conditions of storage
- 14. Terms of dispensing from pharmacies
- 15. Reviews
- 16. Price in pharmacies
Latin name: Glycerin suppositoiums
ATX code: A06AX01; A06AG04
Active ingredient: glycerol (Glycerol)
Manufacturer: Antibiotic S. A. (Antibiotice, SA) (Romania)
Description and photo update: 2019-11-07
Prices in pharmacies: from 162 rubles.
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Glycerin suppositories are a drug for topical use of a laxative effect.
Release form and composition
The drug is produced in the form of rectal suppositories: torpedo-shaped, translucent, with a smooth oily surface, almost colorless with a slight shade of yellow, with a slight characteristic odor (6 pcs. In blisters made of aluminum foil, duplicated with plastic wrap; in a cardboard box 1 or 2 blister packs and instructions for the use of Glycerin suppositories).
Composition for 1 suppository:
- active substance: glycerol - 1405 mg or 2100 mg;
- auxiliary components: purified water, sodium stearate.
Pharmacological properties
Pharmacodynamics
Glycerin suppositories have a laxative effect. Glycerol lubricates and softens hardened feces, irritates the intestinal mucosa, reflexively stimulating its motility, facilitates the passage of fecal masses through the colon, and starts the process of defecation.
Pharmacokinetics
Glycerol is well absorbed through the rectal mucosa. Active metabolism takes place in the liver. From 7 to 14% of the active substance is excreted unchanged. Excretion is carried out by the kidneys.
Indications for use
Glycerin suppositories are used for the symptomatic treatment of constipation of various origins (in cases where oral administration is not possible).
In addition, suppositories are prescribed for the prevention of constipation in patients who are not recommended to strain during the act of defecation, for example, with perianal abscess or fissures in the anus, painful thrombosed hemorrhoids, anorectal stenosis, as well as in patients after myocardial infarction.
Contraindications
Absolute:
- intestinal obstruction (ileus);
- cracks in the anus;
- irritable bowel syndrome;
- exacerbation of hemorrhoids;
- appendicitis;
- tumors and inflammatory diseases of the rectum;
- bleeding from the gastrointestinal tract;
- diarrhea;
- ulcerative rectocolitis;
- abdominal pain of unknown origin;
- children under 5 years of age;
- hypersensitivity to the components of suppositories.
The drug is prescribed with caution in patients with renal insufficiency.
Glycerin suppositories, instructions for use: method and dosage
Glycerin suppositories are administered rectally (into the rectum), 15–20 minutes after breakfast.
Suppositories should be kept in the rectum for at least 5 minutes. Defecation occurs approximately 5–10 minutes after the injection of the suppository. The remains of the drug are excreted with feces.
Recommended doses of Glycerin suppositories for children and adults:
- children aged 5–12 years - 1 suppository 1405 mg once a day;
- adolescents from 12 years old and adults - 1 suppository 2100 mg once a day (if necessary, the dose is increased to 2 suppositories once a day).
Side effects
The drug can cause allergic and local reactions (burning and itching of the anus). The appearance of pains of a spastic nature in the intestinal area is possible. The listed side effects disappear on their own after stopping treatment.
Prolonged use of suppositories can lead to a weakening of the physiological process of emptying and the appearance of irritation of the rectum.
Overdose
With an overdose of glycerol, the patient has frequent loose stools. In this case, therapy should be suspended.
special instructions
Glycerin suppositories should be used with caution in case of nausea and vomiting, allergic reactions and renal dysfunction.
Hands should be thoroughly washed before the introduction of the suppository and after the procedure.
It is not recommended to use the drug regularly. After restoration of natural intestinal motility and normal physiological defecation, treatment should be discontinued. The duration of continuous use of suppositories should be no more than 1 week.
Candles must not be lubricated with solid or liquid mineral oils.
Influence on the ability to drive vehicles and complex mechanisms
Any effect of the drug on the psychomotor functions of a person has not been established.
Application during pregnancy and lactation
Glycerin suppositories can be used during pregnancy and lactation, but only in cases where the expected benefit for the mother is higher than the possible risk of adverse reactions to the fetus or infant.
There are no data on the penetration of glycerol into breast milk.
Pediatric use
Do not prescribe Glycerin suppositories for children under 5 years of age.
Drug interactions
Information on drug interactions with other drugs and substances is not provided.
Analogs
Analogs of Glycerin suppositories are Glycerin, Glycelax, Dexeril, Dolak, RectActive, Glycerol Euro, Slabinorm-Pharmex, Adulaks Kasen-Fleet, Glycerin microclysters for children, Peydolax, etc.
Terms and conditions of storage
Store out of the reach of children at a temperature not exceeding 25 ° C.
The shelf life of suppositories is 3 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews of Glycerin suppositories
According to reviews, Glycerin suppositories are an effective and fast-acting remedy for problems with bowel movement. The drug has a convenient form of release, and due to topical application does not affect the stomach. Suppositories work quickly and gently. The drug is affordable.
There are almost no drawbacks to the drug: most often patients note the existing contraindications and side effects of the drug.
Price for Glycerin suppositories in pharmacies
The price of Glycerin suppositories, regardless of the dosage, averages 150-170 rubles. (for one package containing 12 rectal suppositories).
Glycerin suppositories: prices in online pharmacies
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Drug name Price Pharmacy |
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Glycerin suppositories 1405 mg rectal suppositories 12 pcs. 162 RUB Buy |
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Glycerin suppositories 2100 mg rectal suppositories 12 pcs. 168 RUB Buy |
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
