Erazaban
Erazaban: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. In case of impaired renal function
- 12. Use in the elderly
- 13. Drug interactions
- 14. Analogs
- 15. Terms and conditions of storage
- 16. Terms of dispensing from pharmacies
- 17. Reviews
- 18. Price in pharmacies
Latin name: Erasaban
ATX code: D06BB11
Active ingredient: docosanol (docosanol)
Manufacturer: Bausch & Lomb (USA), Fleet Laboratories Limited (UK)
Description and photo updated: 2018-23-11
Prices in pharmacies: from 326 rubles.
Buy
Erazaban is an external antiviral drug.
Release form and composition
The dosage form of Erazaban is a cream for external use 10%: almost white or white, of a uniform consistency (in a cardboard box 1 tube of 2, 5, 10 or 15 g).
Composition of 1000 mg cream:
- active substance: docosanol - 100 mg;
- auxiliary components: benzyl alcohol - 27 mg, sucrose - 50 mg, propylene glycol - 50 mg, mineral oil - 80 mg, water - 693 mg.
Pharmacological properties
Pharmacodynamics
Docosanol is an antiviral agent. The exact mechanism of its action is unknown.
According to research, docosanol:
- affects the fusion of the virus with the plasma membrane, which leads to inhibition of the penetration of the virus into the cell and its replication;
- promotes the development of cell resistance to infection with lipid-coated viruses, such as Herpes simplex 1 virus.
Docosanol is ineffective against uncoated viruses.
Pharmacokinetics
Intracellular metabolism of docosanol to the main metabolite, docosanoic acid, occurs.
Docosanol and its metabolite are endogenous components of human cell membranes, especially in erythrocytes, kidneys, lungs, and brain.
On intact skin, the cream has minimal absorption, it is not detected in the blood; absorption on the affected skin is moderate. Excretion is carried out by the kidneys.
Indications for use
According to the instructions, Erazaban is prescribed for the treatment of infections of the mucous membranes and skin caused by the Herpes simplex virus type 1, including herpes of the lips.
Contraindications
- intolerance to fructose and sucrase / isomaltase deficiency or glucose / galactose malabsorption syndrome;
- age up to 12 years;
- individual intolerance to the components of the drug.
Erazaban during pregnancy and during breastfeeding should be used with caution, under medical supervision.
Instructions for the use of Erazaban: method and dosage
Erazaban is used externally. The drug is applied with clean hands in a thin layer to the affected and adjacent areas of the skin. A cotton swab can also be used for application.
The recommended frequency of application of the cream is 5 times a day (in the daytime, approximately once every 3 hours). Therapy should be started as early as possible after the onset of the infection, in case of recurrent infection - during the prodromal phase or at the very beginning of the manifestation of the infectious process.
Duration of use is at least 5 days. If necessary, the course can be extended up to 10 days. If symptoms persist, a doctor should be consulted.
Side effects
Possible violations (> 10% - very often;> 1% and 0.1% and 0.01% and <0.1% - rarely; <0.01% - very rare):
- nervous system: very often - headache;
- local reactions: often - itchy skin, rash, dry skin, vulvitis, short redness, peeling, soreness, tingling or burning in the area of application of the drug;
- others: single messages - Quincke's edema.
Overdose
No overdose has been reported.
Erazaban has a low percutaneous absorption, therefore, the occurrence of an overdose with external use is unlikely.
special instructions
It is impossible to apply the cream to the skin near the eyes, avoid getting Erazaban in the eyes.
In order to achieve the best therapeutic effect, therapy should be started immediately at the first signs of the disease (manifested in the form of burning, itching, tingling, redness and a feeling of tension).
With reduced immunity (patients with HIV / AIDS or after bone marrow transplantation), the doctor's recommendations should be followed in the treatment of any infectious diseases.
Application during pregnancy and lactation
- pregnancy: Erazaban should be used under medical supervision after assessing the ratio of the expected benefit with the possible risk;
- lactation period: before using the drug, you must consult a specialist. The doctor must take into account all possible risks and, if necessary, suspend breastfeeding for the duration of drug therapy.
Pediatric use
Erazaban therapy is contraindicated in patients under 12 years of age.
With impaired renal function
Patients with impaired renal function do not need to adjust the dose of the drug.
Use in the elderly
Elderly patients do not need to adjust the dose of the drug.
Drug interactions
With the combined use of Erazaban with immunostimulants, an increase in the effect is noted.
Analogs
The analogues of Erazaban are: Medovir, Aldara, Acyclostad, Acyclovir, Keravort, Priora, Vratizolin, Virolex, Zovirax, Atsivir, Atsik, Vartek.
Terms and conditions of storage
Store at temperatures up to 25 ° C. Keep out of the reach of children.
The shelf life is 3 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Erazaban
Reviews about Erazaban are different. Some consider it an effective drug that quickly relieves the symptoms of herpes in the form of burning and itching. In other cases, there is no improvement at all. Many point to the high cost of the cream and the small volume of packaging.
Price for Erazaban in pharmacies
The approximate price for Erazaban (1 tube of 2 g) is 150–382 rubles.
Erazaban: prices in online pharmacies
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Drug name Price Pharmacy |
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Erazaban 10% cream for external use 2 g 1 pc. 326 RUB Buy |
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Erazaban external cream approx 10% 2g 356 r Buy |
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
