Bisakodyl-Nizhpharm
Latin name: Bisacodyl-Nigpharm
ATX code: A06AB02
Active ingredient: bisacodyl (Bisacodyl)
Manufacturer: JSC "Nizhpharm" (Russia)
Description and photo update: 2020-11-06
Bisacodyl-Nizhpharm is a laxative that stimulates intestinal peristalsis.
Release form and composition
The drug is produced in the form of rectal suppositories: from white to white with a pale yellow shade, torpedo-like, plaque may be present on the surface, and on the cut - a funnel-shaped depression and an air rod (5 pcs. In a blister strip, in a cardboard box 2 packs and instructions for the use of Bisacodyl-Nizhpharm).
1 suppository contains:
- active substance: bisacodyl - 10 mg;
- additional components: solid fat [Supposir (grades NA 15, NAS 50), Witepsol (grades H 15, W 35)] - until a suppository weighing 1250 mg is obtained.
Pharmacological properties
Bisacodyl - an active substance in the Bisacodyl-Nizhpharm suppositories, leads to irritation of the intestinal receptor apparatus, directly affecting the intestinal mucosa, providing an increase in its peristalsis and an increase in mucus production in the large intestine.
Bisacodyl is not absorbed in the intestine. It belongs to prodrugs and when it enters an alkaline environment through hydrolysis, it is biotransformed to a metabolite that irritates the mucous membrane of the gastrointestinal tract (GIT). The effect is observed during the first hour after intrarectal administration of the drug.
Indications for use
- atonic and hypotonic constipation, including constipation after surgery and childbirth, and constipation in the elderly;
- cracks in the anus, proctitis, hemorrhoids (in order to regulate the stool);
- the period of preparation for the implementation of instrumental / radiological studies, surgical operations.
Contraindications
Absolute:
- spastic constipation;
- lesions of the abdominal organs of an inflammatory nature in the acute course;
- strangulated hernia;
- intestinal obstruction;
- bleeding from the gastrointestinal tract;
- peritonitis;
- uterine bleeding;
- acute hemorrhoids;
- cystitis;
- proctitis in an acute course;
- age up to 8 years;
- hypersensitivity to any component of the product.
Relative (use Bisacodyl-Nizhpharm with caution):
- pregnancy and lactation;
- renal and / or hepatic impairment.
Bisacodyl-Nizhpharm, instructions for use: method and dosage
Bisacodyl-Nizhpharm suppositories are intended for rectal administration.
Children 8-14 years old are recommended to administer 1 suppository (10 mg), adolescents over 14 years old and adults - 1-2 suppositories (10-20 mg) per day.
Side effects
During therapy, the most frequently reported undesirable effects are diarrhea and abdominal cramping.
Other undesirable side reactions, the development of which is possible with the use of Bisacodyl-Nizhpharm:
- immune system: hypersensitivity, anaphylactic reactions, angioedema;
- nervous system: dizziness, fainting;
- Gastrointestinal tract: discomfort or spastic pain in the abdomen, discomfort in the rectal area, nausea, vomiting, diarrhea (muscle weakness, dehydration, low blood pressure, cramps), blood in the stool in small quantities, colitis;
- local reactions: irritation and pain, mainly in the presence of anal fissure or ulcerative proctitis.
Overdose
The main symptoms of an overdose of Bisacodyl-Nizhpharm may include a violation of the water-electrolyte balance, hypokalemia, dehydration, diarrhea, and atony of the large intestine.
If intoxication is suspected, symptomatic therapy is indicated.
special instructions
Bisacodyl-Nizhpharm is not used for a long period.
Prolonged use of Bisacodyl-Nizhpharm suppositories can cause fluid loss, electrolyte imbalance, hypokalemia and dehydration, accompanied by thirst and oliguria. Elderly patients or patients with impaired renal function with the development of dehydration may experience a deterioration in the general condition. As a result, in the event of the development of the above pathologies, it is necessary to stop using the drug. The therapy can be resumed only under medical supervision.
During the period of treatment with the drug, traces of blood may appear in the feces, this effect, as a rule, is weak and goes away on its own.
In patients using Bisacodyl-Nizhpharm, the development of dizziness and fainting was noted. According to the analysis carried out, these phenomena are due to stress during bowel movements or a vasovagal reaction to pain in the abdominal region, which can be caused by constipation, and not the use of a laxative.
Influence on the ability to drive vehicles and complex mechanisms
The effect of Bisacodyl-Nizhpharm on the ability to drive vehicles and operate complex equipment has not been studied. However, patients who drive a car or engage in other activities that require quick reactions and increased concentration of attention should be careful during the treatment period, since with intestinal spasm (as a result of a vasovagal reaction), the risk of dizziness and / or fainting increases.
Application during pregnancy and lactation
Pregnant and lactating women should be careful when using Bisacodyl-Nizhpharm suppositories.
Pediatric use
In children under 8 years of age, Bisacodyl-Nizhpharm is not used.
For children 8 years and older, drug therapy is allowed only after consultation and permission from the attending physician.
With impaired renal function
Patients with renal insufficiency should be treated with caution.
For violations of liver function
Patients with hepatic impairment should use Bisacodyl-Nizhpharm with caution.
Drug interactions
- glucocorticosteroids, diuretics: the likelihood of hypokalemia increases with the use of very high doses of bisacodyl;
- cardiac glycosides: the risk of electrolyte imbalance (hypokalemia) is aggravated, which can cause increased sensitivity to the action of these drugs.
Analogs
Bisacodyl-Nizhpharm analogs are Bisacodyl, Bisacodyl-Altfarm, Guttalax, Bisacodyl-Hemofarm, Dulcolax, Bisacodyl-OBL, Bisacodyl-Akrihin, Bisacodyl Grindeks.
Terms and conditions of storage
Keep out of the reach of children at a temperature not exceeding 25 ° C.
Shelf life is 2 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Bisacodyl-Nizhpharm
According to reviews, Bisacodyl-Nizhpharm is an effective laxative. Patients note the rapid action of the drug (usually within 20 minutes after the administration of the suppository), its affordable price, as well as the possibility of using it during pregnancy and breastfeeding.
At the same time, there are often complaints about the development during treatment of undesirable phenomena from the digestive tract, sometimes of a pronounced nature. Due to the risk of addiction to the drug, it is recommended to use it as short a course as possible. In some cases, they indicate an insufficient laxative effect of Bisacodyl-Nizhpharm suppositories.
Price for Bisacodyl-Nizhpharm in pharmacies
The approximate price for Bisacodyl-Nizhpharm, rectal suppositories, 10 mg, is 50 rubles. per package containing 10 pcs.
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
