Ketanov overdose
Ketanov is a drug from the group of non-steroidal anti-inflammatory drugs (NSAIDs). It has a pronounced analgesic (analgesic), moderate antipyretic and anti-inflammatory effect, and therefore is usually used to relieve pain syndromes of various origins, including postoperative.
Source: apteke.net
In the treatment of moderate to severe pain, Ketanov is safer than narcotic analgesics (Omnopon, Morphine, Promedol), since, unlike them:
- does not have a depressing effect on the central nervous system;
- does not depress breathing;
- does not provoke nausea and vomiting;
- does not have a sedative effect;
- does not affect intestinal peristalsis;
- does not cause acute urinary retention;
- does not change hemodynamic parameters (blood pressure, heart rate).
However, this does not mean that Ketanov is completely safe - its abuse leads to serious consequences.
How much Ketanov is needed for an overdose?
The drug is used in two modes:
- if necessary - when a painful attack occurs;
- according to the schedule, the course - regardless of the severity of pain at regular intervals 3-4 times a day.
The average daily dose of Ketanov for an adult is 40 mg (4 tab.). If the drug is used simultaneously both in tablets and in injections, the daily dose can be increased to 90 mg, while the dose of the drug taken orally should not exceed 40 mg per day. The duration of treatment with Ketanov should not exceed 5-7 days. Otherwise, the risk of side effects, including the formation of erosions, peptic ulcers and gastric bleeding on the gastric mucosa, sharply increases.
An overdose of Ketanov usually occurs as a result of an unauthorized increase by the patient of the prescribed dose. The analgesic effect of the tablets does not develop immediately, but after 30-40 minutes, and therefore patients suffering from severe pain do not wait for the analgesic effect and take the drug again, which causes an overdose. Another common misconception that leads to an overdose is that the more pills you take, the faster the effect will develop and the more persistent it will be.
In patients with impaired renal function, an overdose of Ketanov can be caused by taking a therapeutic dose, since it is difficult to remove the drug from the body, which leads to its accumulation and the development of toxic effects.
Signs of overdose
The main signs of an acute overdose of Ketanov are:
- nausea and vomiting;
- pain in the epigastric region;
- drowsiness;
- inhibited state.
Taking Ketanov in a high dose (5-10 times higher than the maximum daily dose) appears with the following symptoms:
- gastrointestinal bleeding;
- arterial hypotension;
- tachycardia;
- breathing disorders;
- acute renal failure;
- coma.
Cases of the development of severe anaphylactic reactions against the background of an overdose with Ketanov are described.
Long-term use of the oral form of the drug can cause damage to the mucous membrane of the stomach and intestines with the development of internal bleeding. This condition is characterized by:
- stomach ache;
- nausea;
- vomiting mixed with fresh blood or "coffee grounds";
- black tarry stools (melena);
- anemia;
- severe general weakness;
- lowering blood pressure;
- tachycardia.
Source: depositphotos.com
First aid for overdose with Ketanov
In case of an acute overdose with Ketanov, it is necessary:
- Rinse the stomach (if no more than 3 hours have passed since the drug was taken). To do this, you need to drink a few glasses of cool water, then, by irritating the root of the tongue, provoke vomiting. It is advisable to repeat the rinsing several times to remove the maximum amount of toxin outside.
- Take Activated carbon (at the rate of 1-2 tablets for every 10 kg of body weight), Enterosgel, Filtrum STI or any other drug with sorbing properties.
- Drink plenty of fluids. This will reduce the concentration of Ketanov in the blood.
If signs of gastric bleeding appear, you need to call an ambulance, and while waiting:
- Lay down the victim, provide him with complete rest.
- Place a cold compress on your stomach.
- Let the victim dissolve the pieces of ice.
Antidote
There is no specific antidote to Ketanov.
When is medical attention needed?
In case of a mild overdose by Ketanov, the victim quickly returns to normal after first aid. If this does not happen or the signs of an overdose are too pronounced, medical attention is needed.
In case of an overdose of moderate and severe, patients are hospitalized in a poison control center. The drug quickly binds to blood plasma proteins, therefore, methods of extracorporeal detoxification (hemodialysis, exchange transfusion, forced diuresis with plasma alkylation) are ineffective. Plasmapheresis helps to improve the condition of patients.
Basically, the treatment is symptomatic, aimed at correcting violations of the functions of vital organs and preventing complications.
Possible consequences
A mild overdose with Ketanov usually has a favorable outcome. In more severe degrees, gastrointestinal bleeding, including life-threatening ones, may develop. Medical hemostasis is not always successful, in some cases it is necessary to resort to emergency surgical intervention.
A severe overdose of Ketanov can lead to the development of acute renal failure. This is a serious complication that requires active treatment, but even in this case, it is not always possible to achieve complete restoration of renal function, as a result of which chronic renal failure is formed.
Elena Minkina Doctor anesthesiologist-resuscitator About the author
Education: graduated from the Tashkent State Medical Institute, specializing in general medicine in 1991. Repeatedly passed refresher courses.
Work experience: anesthesiologist-resuscitator of the city maternity complex, resuscitator of the hemodialysis department.
The information is generalized and provided for informational purposes only. At the first sign of illness, see your doctor. Self-medication is hazardous to health!
