Afrin moisturizing
Afrin moisturizing: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. In case of impaired renal function
- 12. Drug interactions
- 13. Analogs
- 14. Terms and conditions of storage
- 15. Terms of dispensing from pharmacies
- 16. Reviews
- 17. Price in pharmacies
Latin name: Afrin moisturizing
ATX code: R01AA05
Active ingredient: oxymetazoline (Oxymetazoline)
Manufacturer: Bayer Pharma AG (Germany)
Description and photo update: 2019-11-07
Prices in pharmacies: from 219 rubles.
Buy
Afrin moisturizing is a drug for topical application of anti-congestive and alpha-adrenomimetic action.
Release form and composition
Afrin moisturizer is available in the following forms:
- nasal spray 0.05%: a gel-like suspension of white or almost white color with a citrus smell;
- nasal spray 0.05% (chamomile): a gel-like suspension of white or almost white color.
The spray is packaged in 15 ml opaque plastic bottles with a capacity of 23 ml with a fine spray dispenser and a protective cap; in a cardboard box 1 bottle and instructions for the use of Afrin moisturizing.
Composition for 1 ml spray:
- active substance: oxymetazoline hydrochloride - 0.5 mg;
- auxiliary components: sodium carmellose and microcrystalline cellulose (Avicel RC-591), sodium dihydrogen phosphate monohydrate, macrogol-1450, benzyl alcohol, sodium hydrogen phosphate, 17% solution of benzalkonium chloride, disodium edetate dihydrate, glycerol, povidone-K29-32 (lemon flavoring for nasal spray), chamomile flavor (for nasal chamomile spray), purified water.
Pharmacological properties
Pharmacodynamics
Afrin moisturizing belongs to alpha-adrenergic stimulants. It has a vasoconstrictor effect. By narrowing the vessels of the mucous membranes of the paranasal sinuses, nose and Eustachian tube reduces their edema and facilitates nasal breathing in case of infectious-inflammatory and / or allergic rhinitis.
The auxiliary components of the drug (sodium carmellose, microcrystalline cellulose and povidone-K29-32) make the spray viscous, which contributes to a more effective retention of the drug on the mucous membranes and prevents the spray from flowing out of the nose and draining down the throat (compared to a standard aqueous solution).
Macrogol-1450 and glycerol are the components that provide the moisturizing properties of the drug. They help to retain moisture and moisturize dry and irritated nasal mucosa.
According to clinical studies, Afrin moisturizing begins to act within the first minute and retains its therapeutic properties for 12 hours.
Pharmacokinetics
When applied topically, oxymetazoline is almost not detected in the blood.
Indications for use
Afrin moisturizing is used for the symptomatic treatment of infectious-inflammatory and / or allergic rhinitis, sinusitis, hay fever and eustachitis.
Contraindications
Absolute:
- atrophic rhinitis;
- children under 6 years of age;
- combined use with monoamine oxidase inhibitors, as well as a 14-day period after their cancellation;
- increased individual sensitivity to sympathomimetics;
- hypersensitivity to the components of the spray.
Relative (Afrin moisturizing nasal spray is used with caution):
- arterial hypertension;
- chronic heart failure;
- cardiac arrhythmias;
- coronary artery disease;
- severe atherosclerosis;
- chronic renal failure;
- diabetes;
- hyperfunction of the thyroid gland;
- hyperplasia of the prostate with clinical manifestations;
- angle-closure glaucoma;
- During pregnancy and breastfeeding.
Afrin moisturizing, instructions for use: method and dosage
Afrin moisturizing spray is used intranasally.
The bottle must be shaken vigorously before each spraying. Before the first use, you should “calibrate” the spray (press the spray head several times).
Children over 6 years of age and adults are recommended to apply the spray 2 times a day (with an interval of 10-12 hours between sprays). A single dose is 2-3 injections into each nostril. In adults, it can be used 3 times a day.
Side effects
Afrin moisturizing is usually well tolerated by patients, and the resulting adverse reactions are mild and go away on their own.
Possible unwanted effects of the drug:
- dry throat and mouth, transient dryness and burning sensation of the nasal mucosa, sneezing;
- nausea, headache, dizziness;
- palpitations, increased blood pressure;
- sleep disturbances, anxiety, insomnia.
With prolonged therapy, atrophy and reactive hyperemia of the mucous membranes of the nasal cavity and a noticeable decrease in the therapeutic effect (tachyphylaxis) can be observed.
Benzalkonium chloride can cause local skin reactions.
Overdose
With a significant overdose or unintentional intake of oxymetazoline inside, the following symptoms are possible: vomiting, nausea, arrhythmia, shortness of breath, cyanosis, increased blood pressure, tachycardia, fever, depression of the central nervous system, mental disorders.
Symptomatic treatment is performed. When ingested, the stomach is washed and activated charcoal is given to the patient. The use of vasopressor drugs is contraindicated.
special instructions
Afrin moisturizing is not recommended for more than 5 days, as long-term use (more than one week) can lead to recurrence of symptoms of nasal congestion.
Avoid getting the spray in the eyes.
Influence on the ability to drive vehicles and complex mechanisms
When used in recommended doses, Afrin Moisturizing does not affect the patient's ability to drive and work with other potentially dangerous mechanisms, but if reactions such as dizziness occur, it is necessary to refrain from engaging in hazardous activities.
Application during pregnancy and lactation
In pregnant and lactating women, nasal spray is used with caution, assessing the expected benefits of treatment for the mother and the possible risk to the developing fetus or infant.
Pediatric use
Afrin Moisturizing Nasal Spray should not be administered to children under 6 years of age.
With impaired renal function
In patients with chronic renal failure, oxymetazoline is used with caution.
Drug interactions
Afrin moisturizing inhibits the absorption of drugs for local anesthesia and lengthens the duration of their action.
It is not recommended to use oxymetazoline at the same time as other vasoconstrictor drugs, as this increases the likelihood of unwanted side effects.
Concomitant use with tricyclic antidepressants and monoamine oxidase inhibitors increases the risk of hypertension.
Analogs
The analogs of Afrin moisturizing are: Afrin Extra, Afrin, Vicks Active Sinex, Nazivin Sensitiv, Nazivin, Nazol Advance, Nazol, Nesopin, Nazosprey, Noxprey, Oxyfrin, Oxymetazolin, Otrivin Oxy, Sialor Rino, Rinostop Extra, etc.
Terms and conditions of storage
Keep out of the reach of children. Store at a temperature not exceeding 25 ° C.
Shelf life is 2 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews of Afrin moisturizing
According to reviews, Afrin moisturizing copes well with the main task - the elimination of a runny nose and nasal congestion. The vasoconstrictor and moisturizing effects come on very quickly and persist for a long time. The spray is convenient to spray; there is no irritating effect on the mucous membrane of the throat, since the gel-like consistency of the drug does not allow it to drain below.
The main disadvantage is cost. Also, patients note the possibility of addiction and side reactions (headaches, dry nose).
Price for Afrin moisturizing in pharmacies
The price of Afrin moisturizing in the form of a 0.05% nasal spray is 230-310 rubles. for one bottle.
Afrin moisturizing: prices in online pharmacies
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Drug name Price Pharmacy |
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Afrin Moisturizing nasal spray. 0.05% 15ml 219 r Buy |
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Afrin moisturizing 0.05% nasal spray 15 ml 1 pc. 219 r Buy |
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
