Enzistal-P - Instructions For Use, Reviews, Price, Analogues

2024 Author: Rachel Wainwright | [email protected]. Last modified: 2023-12-15 07:39

Enzistal-P

Enzistal-P: instructions for use and reviews

1. 1. Release form and composition
2. 2. Pharmacological properties
3. 3. Indications for use
4. 4. Contraindications
5. 5. Method of application and dosage
6. 6. Side effects
7. 7. Overdose
8. 8. Special instructions
9. 9. Application during pregnancy and lactation
10. 10. Use in childhood
11. 11. Drug interactions
12. 12. Analogs
13. 13. Terms and conditions of storage
14. 14. Terms of dispensing from pharmacies
15. 15. Reviews
16. 16. Price in pharmacies

Latin name: Enzystal-P

ATX code: A09AA02

Active ingredient: pancreatin (pancreatin)

Manufacturer: Torrent Pharmaceuticals, Ltd. (Torrent Pharmaceuticals, Ltd.) (India)

Description and photo updated: 2018-23-11

Prices in pharmacies: from 57 rubles.

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Enzistal-P is a drug containing enzymes (digestive enzymes) that help improve the digestion process.

Release form and composition

Enzistal-P is produced in the form of enteric-coated tablets: biconvex, round, pink (10 pcs. In blisters; in a cardboard box 1, 2, 4 or 8 blisters).

1 tablet contains:

• active substance: pancreatin - 116.17 mg [with a minimum enzymatic activity of 250 units of protease. Ph. Eur. (Units of action of the European Pharmacopoeia), lipase 3500 UNITS. Ph. Eur., Amylase 4200 U Ph. Eur.];
• additional components: microcrystalline cellulose, colloidal silicon dioxide, lactose monohydrate, magnesium stearate, sodium carboxymethyl starch;
• enteric coating: diethyl phthalate, macrogol 6000, cellulose acetate phthalate, azorubin (carmoisin), white beeswax, titanium dioxide, hypromellose.

Pharmacological properties

Pharmacodynamics

Enzistal-P is a digestive enzyme preparation that replenishes the deficiency of pancreatic enzymes and has amylolytic, proteolytic and lipolytic effects. The pancreatic enzymes included in the composition of the product, such as alpha-amylase, lipase, chymotrypsin, trypsin, are involved in the breakdown of fats to fatty acids and glycerol, proteins to amino acids, starch to monosaccharides and dextrins. The active substance Enzistal-P contributes to the normalization of digestion processes, improvement of the functional state of the gastrointestinal tract (GIT), provides complete and rapid digestion of food, reduces the severity of symptoms resulting from indigestion (feeling of fullness and heaviness in the stomach, diarrhea, flatulence). Trypsin contained in pancreatin inhibits the stimulated secretion of the pancreas,showing an analgesic effect. From the dosage form, pancreatic enzymes are released in the small intestine (under the influence of its alkaline environment), since the tablets are coated with a coating that protects against the action of gastric juice.

Indications for use

• exocrine pancreatic insufficiency (as a means of replacement therapy): chronic pancreatitis, flatulence, dyspepsia, non-infectious diarrhea, cystic fibrosis, pancreatectomy, condition after radiation;
• conditions after resection of the stomach and small intestine, accompanied by impaired absorption of food;
• Remheld syndrome (gastrocardiac syndrome);
• prolonged immobilization, sedentary lifestyle, impaired chewing function (to improve food digestion);
• the presence of inaccuracies in nutrition in persons with normal gastrointestinal tract function - irregular nutrition, eating a large amount of food or hard-to-digest, fatty foods.

According to the instructions, Enzistal-P is also recommended for use in preparation for X-ray and ultrasound examination (US) of the abdominal organs.

Contraindications

• age up to 3 years;
• acute pancreatitis;
• stage of exacerbation of chronic pancreatitis;
• hypersensitivity to the components of the drug.

Instructions for use of Enzistal-P: method and dosage

Enzistal-P is taken orally. Simultaneously with a meal or immediately after a meal, the tablets are swallowed whole without chewing and washed down with plenty of liquid.

The recommended average dose for adults is 1-2 tablets. Taking into account the degree of insufficiency of the pancreas and the quantity / quality of food consumed, if necessary, it is allowed to increase the dose to 2-4 tablets. Doses in excess of 4 tablets can only be taken as directed by your doctor. The maximum daily dose of lipase should not exceed 15-20 thousand units / kg.

For children, the dosage regimen is established by the doctor, in most cases it is recommended to take 1 tablet of Enzistal-P 3 times a day with meals.

The duration of treatment is determined individually. In case of digestive disorders due to an error in the diet, the course can be several days, with replacement therapy - from several months to several years.

Side effects

While taking Enzistal-P, the development of allergic reactions was sometimes observed, in rare cases, the appearance of nausea, diarrhea / constipation, and discomfort in the epigastric region was noted.

With prolonged use of the drug in high doses, the occurrence of such a side effect as hyperuricosuria was recorded, and when taking high doses, patients with cystic fibrosis develop strictures in the ascending colon and in the ileocecal region.

Overdose

Symptoms of an overdose of Enzistal-P may include hyperuricemia and hyperuricosuria, in children - constipation.

If you suspect an overdose, you must stop taking the drug and conduct symptomatic therapy.

special instructions

There is no data.

Application during pregnancy and lactation

During pregnancy and lactation, the enzyme is used only when the expected benefit of the treatment to the mother outweighs the possible threat to the health of the fetus or baby.

Pediatric use

In pediatrics, Enzistal-P is contraindicated in children under 3 years of age.

Drug interactions

With the combined reception of Enzistal-P with iron preparations, there may be a decrease in the absorption of the latter.

Analogs

Enzistal-P analogs are: Gastenorm forte, Creon 10,000, Gastenorm forte 10,000, Creon 25,000, Creon Micro, Creon 40,000, Mezim 20,000, Mezim forte, Pangrol 25,000, Micrasim, PanziKam, Panzim forte, Pancreasim, Pancreatin, Pancreatin forte, Pancreatin-LekT, Penzital, Hermital.

Terms and conditions of storage

Keep out of the reach of children at a temperature not exceeding 25 ° C.

The shelf life is 3 years.

Terms of dispensing from pharmacies

Available without a prescription.

Reviews about Enzistal-P

According to reviews, Enzistal-P is an effective drug used for digestive problems. Patients who have taken the enzyme agent note a rapid relief of symptoms caused by impaired absorption of food, as well as the normalization of digestion processes.

There are no reports of the development of side effects.

The price of Enzistal-P in pharmacies

The price of Enzistal-P for a pack containing 20 tablets is approximately 70 rubles.

Enzistal-P: prices in online pharmacies

Drug name Price Pharmacy

Enzistal-P enteric-coated tablets 20 pcs. RUB 57 Buy

Anna Kozlova Medical journalist About the author

Education: Rostov State Medical University, specialty "General Medicine".

Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!