Proxofelin - Instructions For The Use Of Eye Drops, Price, Reviews

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Proxofelin - Instructions For The Use Of Eye Drops, Price, Reviews
Proxofelin - Instructions For The Use Of Eye Drops, Price, Reviews

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Proxopheline

Proxofelin: instructions for use and reviews

  1. 1. Release form and composition
  2. 2. Pharmacological properties
  3. 3. Indications for use
  4. 4. Contraindications
  5. 5. Method of application and dosage
  6. 6. Side effects
  7. 7. Overdose
  8. 8. Special instructions
  9. 9. Application during pregnancy and lactation
  10. 10. Use in childhood
  11. 11. Drug interactions
  12. 12. Analogs
  13. 13. Terms and conditions of storage
  14. 14. Terms of dispensing from pharmacies
  15. 15. Reviews
  16. 16. Price in pharmacies

Latin name: Proxophelin

ATX code: S01EX

Active ingredient: butylaminohydroxypropoxyphenoxymethyl methyloxadiazole (proxodolol) [Butylaminohydroxypropoxyphenoxymethyl methyloxadiazole (proxodolol)]; clonidine (Clonidine)

Manufacturer: Moscow Endocrine Plant FSUE (Russia)

Description and photo update: 2019-08-07

Prices in pharmacies: from 144 rubles.

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Eye drops Proxophelin
Eye drops Proxophelin

Proxophelin is a combined antiglaucoma drug.

Release form and composition

The drug is available in the form of eye drops: colorless or slightly colored liquid with a transparent structure (1.5; 2 or 5 ml each in polymer tube-droppers, in a cardboard box 1, 2, 4, 5 or 10 tube-droppers; 5 ml each or 10 ml in polymer dropper bottles, in a cardboard box 1 or 2 dropper bottles. Each pack also contains instructions for the use of Proxofelin).

1 ml of solution contains:

  • active ingredients: proxodolol - 10 mg; clonidine (clonidine) - 2.5 mg;
  • auxiliary components: benzethonium chloride, sodium chloride, citric acid monohydrate, sodium citrate pentasesquihydrate, water for injection.

Pharmacological properties

Proxophelin is a combined antiglaucoma drug with a vasodilating effect.

The mechanism of action of the drug is due to the property of the active components, to suppress the production of aqueous humor and to increase its outflow, which leads to a decrease in intraocular pressure.

After instillation, the therapeutic effect occurs in 1 / 4-1 / 2 hours, after 2-6 hours it reaches a maximum and lasts 24 hours. The drug does not affect the size of the pupil, accommodation or refraction.

Indications for use

The use of Proxofelin is indicated for various forms of glaucoma (open-angle, closed-angle, secondary) to reduce intraocular pressure in cases where monotherapy with proxodolol or clonidine does not have a sufficient effect.

For angle-closure glaucoma, the drug should be prescribed in combination with miotic agents.

Contraindications

Absolute:

  • chronic heart failure;
  • atrioventricular block II – III degree;
  • bradycardia;
  • arterial hypotension;
  • chronic obstructive pulmonary disease;
  • bronchial asthma;
  • period of pregnancy;
  • breast-feeding;
  • childhood;
  • hypersensitivity to the components of the drug.

Proxofelin eye drops should be used with caution in patients with gastric ulcer and duodenal ulcer, patients with type 1 diabetes mellitus.

Proxofelin, instructions for use: method and dosage

Eye drops Proxofelin are used by instillation into the conjunctival sac of the eye.

Recommended dosage: 1 drop 2 times a day.

When prescribing the drug in combination with pilocarpine, pilocarpine should be instilled 1-3 times a day.

Side effects

Against the background of instillations, in isolated cases, undesirable phenomena such as dry mouth, weakness, drowsiness, dizziness, a decrease in blood pressure (BP) or a slowdown in heart rate may appear.

Overdose

  • symptoms: increased severity of side effects;
  • treatment: immediate withdrawal of the drug.

special instructions

Do not touch the eye with the dropper tip. After each procedure, the dropper tube must be tightly closed.

It is recommended to stop wearing soft contact lenses during the treatment period.

If rigid lenses are used, they should be removed and put on again no earlier than 15–20 minutes after the procedure before instillation.

Influence on the ability to drive vehicles and complex mechanisms

During the period of treatment, caution should be exercised in patients whose activities require visual acuity. If, after instillation, the clarity and sharpness of visual perception is temporarily lost, it is required to refrain from driving or working with complex equipment.

Application during pregnancy and lactation

The use of Proxofelin is contraindicated during gestation and lactation.

If it is necessary to prescribe drops to a pregnant woman, the doctor must balance the expected benefits for her with the potential risk to the fetus / newborn.

There is insufficient data on the penetration of proxodolol and / or clonidine into human breast milk, therefore, it is recommended to stop breastfeeding during treatment.

Pediatric use

Due to the lack of sufficient experience with the use of Proxofelin in pediatric practice, the appointment of the drug in childhood is contraindicated.

Drug interactions

With the simultaneous use of Proxofelin with 1% pilocarpine solution, the hypotensive effect is enhanced by the value of intraocular pressure.

Concomitant therapy with systemic alpha or beta blockers may contribute to a more pronounced antihypertensive effect.

Analogs

Proxofelin analogues are Fotil, Cosopt, Timolol, Betoptik, Pilocarpin, Xalatan, Dorzopt Plus and others.

Terms and conditions of storage

Keep out of the reach of children.

Store at temperatures up to 15 ° C in a dark place.

Shelf life is 2 years.

Terms of dispensing from pharmacies

Dispensed by prescription.

Reviews of Proxofelin

The few reviews about Proxophelin are positive. Patients report that in open-angle glaucoma, regular use of the drug for one month helped to slow the progression of the disease.

The price of Proxopheline in pharmacies

The price of Proxophelin for a package containing 5 tubes of 1.5 ml droppers can average 225 rubles.

Proxopheline: prices in online pharmacies

Drug name

Price

Pharmacy

Proxophelin 1% eye drops 1.5 ml 5 pcs.

144 RUB

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Maria Kulkes
Maria Kulkes

Maria Kulkes Medical journalist About the author

Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".

Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!

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