Trombogel 1000
Trombogel 1000: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Drug interactions
- 11. Analogs
- 12. Terms and conditions of storage
- 13. Terms of dispensing from pharmacies
- 14. Reviews
- 15. Price in pharmacies
Latin name: Trombogel 1000
ATX code: B01AB01
Active ingredient: sodium heparin (Heparin natrium)
Manufacturer: RUE "Belmedpreparaty" (Republic of Belarus)
Description and photo update: 2020-25-02
Prices in pharmacies: from 123 rubles.
Buy
Thrombogel 1000 is a direct-acting anticoagulant drug used topically.
Release form and composition
Dosage form - gel for local and external use, light yellow or colorless, with a specific odor (in a cardboard box 1 tube containing 15 or 30 g of gel, and instructions for the use of Trombogel 1000).
Composition of 1 g of gel:
- active substance: sodium heparin - 1000 international units (ME);
- auxiliary components: purified water - up to 1 g; triethanolamine (trolamine) - to obtain a pH in the range from 5.5 to 7.5; ethanol - 100 mg; propyl parahydroxybenzoate - 0.5 mg; methyl parahydroxybenzoate - 1.5 mg; levomenthol - 0.5 mg; carbopol 980 NF (carbomer) - 11 mg.
Pharmacological properties
Pharmacodynamics
Sodium heparin is one of the direct-acting anticoagulants (a group of medium molecular weight heparins). It is characterized by local antithrombotic, antiexudative and moderately anti-inflammatory activity when applied externally.
After applying the gel, the fibrinolytic properties of the blood are activated, the action of hyaluronidase is inhibited and the formation of thrombin stops. The active substance of the drug, gradually released and passing through the skin, reduces the inflammatory process, exhibits antithrombotic properties, increases microcirculation and activates tissue metabolism, which leads to a decrease in tissue swelling, acceleration of the resorption of blood clots and hematomas.
Pharmacokinetics
Heparin sodium is characterized by low absorption when applied externally.
Indications for use
- thrombophlebitis of superficial veins (prevention and therapy);
- hemorrhoids, including postpartum;
- superficial mastitis;
- post-infusion and post-injection phlebitis;
- lymphangitis;
- elephantiasis;
- localized infiltrates and edema;
- superficial periphlebitis;
- subcutaneous hematoma;
- bruises and injuries, including joints, tendons, muscle tissue.
Contraindications
Absolute:
- traumatic violation of the integrity of the skin;
- ulcerative necrotic processes;
- established hypersensitivity to the components of the drug.
Relative (the use of Trombogel 1000 requires special care and careful medical supervision):
- thrombocytopenia;
- increased tendency to bleeding.
Trombogel 1000, instructions for use: method and dosage
Gel Trombogel 1000 is intended for local and external use.
When applied externally, a single dose of the drug (a column with a length of 3 to 10 cm - 0.5-1 g) is applied to the affected area of the skin (with a diameter of 3-5 cm) from 1 to 3 times a day.
For the treatment of thrombosis of hemorrhoidal veins, the drug is applied to coarse calico pads, which are then applied directly to the restrained nodes and fixed with a bandage. A swab soaked in the drug can also be inserted rectally. The duration of treatment is 3-4 days.
In case of a leg ulcer, the inflamed skin around the ulcer is lubricated with gel 2-3 times daily, until the inflammatory phenomena disappear - on average, from 3 to 7 days. A longer course of therapy is allowed as directed by a doctor.
Side effects
During therapy with Thrombogel 1000, the development of undesirable phenomena in the form of allergic reactions and skin flushing is possible.
Overdose
Since the absorption of sodium heparin is low, the development of an overdose is unlikely. Such cases have not been described.
With prolonged use of the gel, the development of symptoms of intoxication in the form of hemorrhagic complications is possible.
In this case, it is recommended to cancel the drug; if necessary, the appointment of protamine sulfate (heparin antagonist).
special instructions
Gel Trombogel 1000 cannot be used in the presence of purulent processes, applied to mucous membranes and open wounds. The drug is not recommended for patients with deep venous thrombosis.
Application during pregnancy and lactation
There are no data regarding the use of Trombogel 1000 during pregnancy and during breastfeeding.
Drug interactions
Heparin sodium should not be used topically in combination with tetracyclines, antihistamines and non-steroidal anti-inflammatory drugs.
Analogs
Analogs of Trombogel 1000 are Trombless, Heparin-sodium Brown, Heparin 1000, Lioton 1000, Heparin-Ferein, Heparin sodium, Lavenum, Heparin, Heparin-Akrikhin 1000, Heparin J. and others.
Terms and conditions of storage
Store at temperatures up to 25 ° C. Keep out of the reach of children.
Shelf life is 2 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Trombogel 1000
Patients generally leave positive reviews about Trombogel 1000. The advantages most often include its high efficiency and budgetary cost.
The most significant disadvantage is the need to use the gel regularly.
Price for Trombogel 1000 in pharmacies
The approximate price for Trombogel 1000, gel for local and external use, (1 tube of 30 g in a package) is from 117 to 179 rubles.
Trombogel 1000: prices in online pharmacies
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Drug name Price Pharmacy |
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Thrombogel 1000 1000 IU / g gel for external use 30 g 1 pc. 123 r Buy |
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Thrombogel 1000 gel 30g 209 RUB Buy |
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
