Stresam
Strezam: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. In case of impaired renal function
- 12. For violations of liver function
- 13. Drug interactions
- 14. Analogs
- 15. Terms and conditions of storage
- 16. Terms of dispensing from pharmacies
- 17. Reviews
- 18. Price in pharmacies
Latin name: Stresam
ATX code: N05BX
Active ingredient: Etifoxin (Etifoxine)
Manufacturer: BIOCODEX, France
Description and photo update: 2018-14-05
Prices in pharmacies: from 453 rubles.
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Strezam is a tranquilizer, anxiolytic drug.
Release form and composition
Dosage form of Strezam - capsules: gelatinous, smooth, shiny, size No. 2, with a blue lid and white body; the contents of the capsule are white with a yellowish tinge or white powder (12 or 20 pieces in a blister made of aluminum / PVC, 2 or 3 blisters in a carton box).
Composition of 1 capsule:
- active substance: etifoxine hydrochloride - 50 mg;
- excipients: lactose monohydrate - 119 mg, talc - 15 mg, microcrystalline cellulose - 10 mg, magnesium stearate - 3 mg, anhydrous colloidal silicon dioxide - 3 mg;
- shell: indigo carmine, titanium dioxide, gelatin.
Pharmacological properties
Pharmacodynamics
It is a derivative of benzoxazine, has anxiolytic activity, has a slight sedative effect. Does not cause withdrawal or addiction. Selectively affects the chlorine channels (SG channels) of the supramolecular GABA-benzodiazepine-chlorionophore receptor complex, reducing GABA-ergic transmission.
Pharmacokinetics
Absorption from the gastrointestinal tract is rapid. It is actively metabolized in the liver to the formation of some metabolites. Diethylethifoxine (one of the metabolites) is active and its half-life is approximately 20 hours.
Passes through the placental barrier.
The duration of reaching the maximum concentration in the blood is 2-3 hours, the half-life is approximately 6 hours.
It is excreted in the form of metabolites mainly in the urine, as well as unchanged in small volumes. Also excreted in the bile.
Indications for use
Strezam is indicated for the elimination of fear, internal tension, increased irritability, anxiety, mood reduction (including diseases on the dental background, especially of a cardiovascular nature).
Contraindications
- hypersensitivity to the components of the drug;
- myasthenia gravis;
- shock conditions;
- severe renal / liver dysfunction;
- age up to 18 years.
Instructions for use of Strezam: method and dosage
Strezam is administered orally (by mouth) with a little water.
The dose of the medication is determined by the attending physician individually, depending on the patient's condition.
Usually assigned to 1 pc. 3 times a day or 2 pcs. 2 times a day. The maximum daily dose is 150-200 mg.
The duration of therapy is from several days to 4-6 weeks (depending on the patient's condition).
Side effects
- drowsiness (appearing in the first days of therapy and usually disappearing on its own during treatment);
- allergic reactions - Quincke's edema, urticaria, skin rash.
Overdose
In cases of an overdose of Strezam, the following symptoms are observed: excessive drowsiness and lethargy.
Treatment of the above reactions requires gastric lavage with large volumes of water and symptomatic treatment.
special instructions
Due to the presence of lactose in the composition of the medication, the drug cannot be used for galactosemia, malabsorption of galactose and glucose, as well as for lactase deficiency.
If you skip taking Strezam, it is not recommended to double the dose the next time you take it.
Do not combine the drug with alcoholic beverages.
It is not recommended to exceed the dose prescribed by your doctor.
Influence on the ability to drive vehicles and complex mechanisms
Due to the risk of drowsiness, it is necessary during the period of therapy to refrain from driving vehicles and engaging in other activities that require increased attention.
Application during pregnancy and lactation
Stresam is not recommended during pregnancy. If it occurs during therapy, it is necessary to consult with a specialist about the continuation of treatment. You should not use the drug during breastfeeding.
Pediatric use
According to the instructions, Stresam is contraindicated in persons under the age of 18.
With impaired renal function
It is contraindicated to use Stresam according to indications in patients with severe renal impairment.
For violations of liver function
In severe liver dysfunction, Strezam is contraindicated.
Drug interactions
It potentiates the effect of opioid drugs, barbiturates, analgesics, antihistamines and hypnotics, antipsychotics and other drugs that depress the central nervous system, and also enhances the effect of alcohol.
Analogs
Strezam analogs are: Tranquilar, Oksilidin, Meprobamat, Temazepam, Amisil.
Terms and conditions of storage
Store at temperatures between 15 ° C and 25 ° C. Keep out of the reach of children.
Shelf life is 3 years.
Terms of dispensing from pharmacies
Dispensed by prescription.
Reviews about Stresam
There are few reviews about Strezam, indicating its effectiveness. Forum visitors who have taken the drug rate it a solid four on a five-point scale. Among the advantages of Strezam, the absence of drowsiness, a mild sedative effect, and a rapid elimination of anxiety are noted. Not without its drawbacks, in particular, many patients are not satisfied with the rather high price of the drug.
According to doctors' reviews, Stresam will be especially useful for people in whom taking other sedatives causes severe drowsiness. And although this side effect is mild, it is recommended to observe maximum vigilance when driving a car, and completely abandon the control of complex mechanisms for the period of drug therapy.
In addition, doctors do not recommend using the drug for the treatment of anxiety-phobic disorders in children and adolescents under the age of 18.
The price of Strezam in pharmacies
The price for Strezam is about 350 rubles (in a package of 24 capsules), 470-650 rubles (in a package of 60 capsules).
Stresam: prices in online pharmacies
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Drug name Price Pharmacy |
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Strezam capsules 50mg 24 pcs. 453 r Buy |
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Strezam 50 mg capsules 24 pcs. 453 r Buy |
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Strezam 50 mg capsules 60 pcs. RUB 638 Buy |
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Strezam capsules 50mg 60 pcs. RUB 781 Buy |
Anna Kozlova Medical journalist About the author
Education: Rostov State Medical University, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
