Sibektan
Sibektan: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. In case of impaired renal function
- 12. For violations of liver function
- 13. Use in the elderly
- 14. Drug interactions
- 15. Analogs
- 16. Terms and conditions of storage
- 17. Terms of dispensing from pharmacies
- 18. Reviews
- 19. Price in pharmacies
Latin name: Sibectan
ATX code: A05C
Active ingredient: Birch leaves extract (Betulae foliorum extract) + St. John's wort extract (Hyperici perforati herbae extract) + Milk thistle fruit extract (Silybi mariani fructuum extract) + Common tansy flowers extract (Tanaceti floridis extract)
Producer: Pharmcenter VILAR, JSC (Russia)
Description and photo update: 2019-08-07
Prices in pharmacies: from 128 rubles.
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Sibektan is a choleretic agent of plant origin.
Release form and composition
Dosage form - tablets: round, biconvex, from grayish-green to grayish-brown or dark gray interspersed (10, 15, 20 and 30 pieces each in blister contour packs, in a cardboard box 1, 2 or 3 packages 10 tablets; 2 packs of 15 tablets; 1 or 2 packs of 20 tablets; 1 pack of 30 tablets, as well as instructions for using Sibektan).
Sibektan's composition for 1 tablet:
- dry extract of milk thistle fruit (dry extract of silymar) - 30 mg, including the amount of flavolignans - 65% (in terms of silybin and dry matter);
- dry extract of flowers of common tansy (dry extract of tanacechol) - 25 mg, including the sum of flavonoids and phenolcarboxylic acids - 55% (in terms of luteolin and dry matter);
- dry extract of St. John's wort - 25 mg, including the amount of flavonoids - 8% (in terms of rutin and dry matter);
- dry birch extract - 20 mg, including phenolic compounds - 5% (in terms of rutin and dry matter).
Pharmacological properties
Pharmacodynamics
Sibektan is a herbal choleretic agent. It has hepatoprotective, choleretic, antioxidant and membrane stabilizing effects. Strengthens the regeneration processes. Reduces the processes of lipid peroxidation in the liver and fermentation, enhances the detoxification function of the liver, normalizes lipid and pigment metabolism, and stimulates the regeneration of the damaged gastric mucosa.
Sibektan has a beneficial therapeutic effect in chronic persistent hepatitis, chronic cholecystitis, hypomotor dyskinesia of the gallbladder, as well as fatty degeneration of the liver, including alcoholic genesis.
The drug improves biochemical parameters, reflecting the state of the main functions of the liver, and the general condition of the patient: eliminates pain in the right hypochondrium, bitterness in the mouth, heartburn, nausea, etc.
Pharmacokinetics
Information not provided by the manufacturer.
Indications for use
As a hepatoprotective agent, Sibektan is used in the following cases:
- chronic persistent hepatitis;
- hypomotor dyskinesia of the gallbladder;
- chronic cholecystitis.
Sibektan is prescribed as part of the complex therapy of such diseases:
- cirrhosis of the liver;
- fatty degeneration of the liver of alcoholic genesis.
Contraindications
- cholelithiasis (gallstone disease);
- age up to 18 years;
- period of pregnancy and lactation;
- hypersensitivity to any component in Sibektan.
Sibektan, instructions for use: method and dosage
Sibektan tablets should be taken orally 20-40 minutes before meals.
Adults are prescribed 2 tablets 4 times a day for a course of 20-25 days.
If required, therapy is extended for another 10-15 days.
Side effects
In some patients, Sibektan may cause allergic effects.
Overdose
Overdose cases have not been recorded to date.
special instructions
Unlike other hepatoprotective drugs, Sibektan can be used in patients with inflammatory conditions of the gastric mucosa and duodenum.
Influence on the ability to drive vehicles and complex mechanisms
Sibektan does not adversely affect the speed of reactions and the ability to concentrate.
Application during pregnancy and lactation
During pregnancy and breastfeeding, taking the drug is contraindicated.
Pediatric use
Sibektan is not used in pediatrics.
With impaired renal function
No information available.
For violations of liver function
Sibektan is used according to indications.
Use in the elderly
There is no data on the need for dose adjustment for elderly patients.
Drug interactions
Information not provided by the manufacturer.
Analogs
Sibektan's analogues are Bongigar, VG-5, Gepabene, Liv. 52 K, Holebil, Choleretic collection No. 2, Choleretic collection No. 3, Kavehol, Tanacehol, Phytohepatol, Flamin, Cholemax, Holos, Holosas, Hofitol, etc.
Terms and conditions of storage
Store at a temperature not exceeding 25 ° C in a dark, dry place out of reach of children.
The shelf life is 3 years.
Terms of dispensing from pharmacies
Available without a prescription.
Reviews about Sibektan
Medical specialists leave positive reviews about Sibektan, since it is a drug with proven effectiveness. In the course of a clinical study, the results of patients with chronic viral hepatitis aged 23 to 51 years who received treatment with interferon-α drugs before the start of the study were studied. Patients took 2 Sibektan tablets 4 times a day for 30-40 days. The main criteria for evaluating the efficacy of the drug were biochemical parameters observed before and after the course of treatment, as well as the dynamics of clinical symptoms. In addition, during the study, all adverse events were recorded, on the basis of which the safety of the herbal remedy was assessed.
The positive dynamics of biochemical after therapy was observed in 2 / 3 patients with mild and moderate activity of the process, 50% of patients with severe activity of the process. Favorable dynamics were also observed in patients with ineffective interferon therapy.
Of the side effects, only 1 patient had an increase in stool up to 3-4 times a day, but drug withdrawal was not required.
Thus, according to the conclusion of medical specialists, Sibektan is effective in the treatment of chronic viral hepatitis and is well tolerated. However, the normalization of biochemical parameters is noted within a short period of time, therefore, the issue of a longer treatment is being considered.
The price of Sibektan in pharmacies
The average price for Sibektan for a pack of 30 tablets is 139 rubles.
Sibektan: prices in online pharmacies
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Drug name Price Pharmacy |
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Sibektan 100 mg tablets 30 pcs. RUB 128 Buy |
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
