Mometason-Akrikhin
Mometason-Akrikhin: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. Drug interactions
- 12. Analogs
- 13. Terms and conditions of storage
- 14. Terms of dispensing from pharmacies
- 15. Reviews Mometasone-Akrikhin
- 16. Price in pharmacies
Latin name: Mometasone-Akrichin
ATX code: D07AC13
Active ingredient: mometasone (mometasone)
Manufacturer: Akrikhin, JSC (Russia)
Description and photo update: 28.11.2018
Prices in pharmacies: from 180 rubles.
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Mometasone-Akrikhin is a glucocorticosteroid (GCS), a drug for local use with antipruritic, anti-inflammatory and antiexudative effects.
Release form and composition
The drug is available in the form of a cream for external use 0.1%: a dense mass of white or almost white color (15 g or 30 g each in aluminum tubes, in a cardboard box 1 tube and instructions for the use of Mometasone-Akrihin).
100 g of cream contains:
- active substance: mometasone furoate - 0.1 g;
- auxiliary components: cetostearyl alcohol, hexylene glycol, white beeswax, glyceryl monostearate 40–55, aluminum starch octenyl succinate, macrogol cetostearate (macrogol 20 cetostearyl ether), titanium dioxide, phosphoric acid diluted or concentrated phosphoric acid in the form of 10% orthophosphoric acid peeled.
Pharmacological properties
Pharmacodynamics
Mometasone-Akrikhin is a topical drug with anti-inflammatory, antipruritic, antiexudative effects. Its active ingredient, mometasone, is a synthetic GCS. The mechanism of action of mometasone is due to its ability to induce lipocortins, proteins that inhibit phospholipase A2. This causes inhibition of the release of arachidonic acid and disruption of the biosynthesis of inflammatory mediators - prostaglandins and leukotrienes.
Pharmacokinetics
8 hours after application to intact skin (without an occlusive dressing), about 0.4% of the drug is absorbed into the systemic circulation.
Indications for use
The use of Mometasone-Akrikhin cream is indicated for the weakening and elimination of itching and inflammation in dermatoses amenable to GCS therapy.
Contraindications
- perioral dermatitis;
- rosacea;
- bacterial, fungal or viral (chickenpox, Herpes simplex, Herpes zoster) skin infection;
- syphilis;
- tuberculosis;
- post-vaccination reactions;
- age up to 6 months;
- application to large areas of the skin and / or long-term treatment during pregnancy and breastfeeding;
- established hypersensitivity to glucocorticosteroids;
- individual intolerance to the components of the drug.
Care should be taken to use Mometasone-Akrikhin when treating the skin of the face, applying it to the folds of the body, using occlusive dressings, affecting large areas of the skin, the need for a long course of therapy (especially in children).
Mometasone-Akrikhin, instructions for use: method and dosage
The cream is applied externally by applying a thin layer to the affected skin.
Recommended frequency of procedures: once a day.
The duration of the course of treatment is determined individually, it depends on the age, effectiveness and tolerance of therapy by the patient, the presence of side effects or their severity.
Side effects
- rarely: itching, burning sensation, dryness and irritation of the skin, folliculitis, hypertrichosis, perioral dermatitis, hypopigmentation, acne, skin maceration, contact dermatitis of allergic origin, secondary infection, signs of skin atrophy, prickly heat, striae, the formation of papules or pustules;
- possible: against the background of the use of occlusive dressings, long-term therapy and / or treatment of large areas of the skin (especially in childhood) - Cushing's syndrome, adrenal insufficiency and other undesirable phenomena of the systemic action of GCS.
Overdose
Symptoms: suppression of the function of the hypothalamic-pituitary-adrenal system, secondary adrenal insufficiency.
Treatment: the appointment of symptomatic therapy; careful monitoring of the patient's condition is required, if necessary - restoration of the electrolyte balance, drug withdrawal (after prolonged therapy, withdrawal should be carried out gradually).
special instructions
It should be borne in mind that applying the cream to large areas of the skin for a long time (especially when using occlusive dressings) increases the risk of systemic exposure to mometasone. Therefore, in these cases, control of the function of the hypothalamic-pituitary-adrenal system is required.
Do not allow the cream to get into your eyes.
The use of GCS can cause slow wound healing. In addition, glucocorticosteroids can alter the symptomatology of some skin diseases and can be difficult to diagnose.
After prolonged use of Mometasone-Akrikhin, its cancellation should be done gradually, since a sudden cancellation of therapy can cause the development of rebound syndrome.
Application during pregnancy and lactation
The safety of using the cream during gestation has not been established. GCS overcome the placental barrier and can negatively affect the development of the fetus. Therefore, care should be taken to avoid a long period of treatment or the use of high doses of Mometasone-Akrikhin.
Due to the fact that mometasone can be excreted in breast milk, if it is necessary to use large doses of the cream and / or use it for an extended period, it is recommended to stop breastfeeding.
Pediatric use
The appointment of Mometasone-Akrikhin cream is contraindicated for the treatment of children under the age of 6 months.
For the treatment of children, the minimum effective dose of the drug should be used for a short period.
The safety and effectiveness of topical application of the cream in children for more than one and a half months have not been established. The duration of the course of treatment in children aged 6 to 24 months should not exceed 5 days.
When using any topical corticosteroids, children are at a higher risk of suppression of the function of the hypothalamic-pituitary-adrenal system and the development of Cushing's syndrome. Long-term therapy with corticosteroids can cause impaired growth and development of the child.
Drug interactions
The interaction of mometasone in the form of a cream with simultaneous use with other drugs has not been established.
Analogs
Analogs of Mometasone-Akrikhin are: ointments - Avecort, Monovo, Momat, Mometason, Momederm, Elokom; creams - Gistan-N, Monovo, Momat, Silkaren, Elokom; solutions for external use - Momederm, Elokom Lotion.
Terms and conditions of storage
Keep out of the reach of children.
Store at 15-25 ° C.
Shelf life is 2 years.
Terms of dispensing from pharmacies
Dispensed by prescription.
Reviews about Mometasone-Akrikhin
Reviews of Mometasone-Akrikhin are positive. Patients indicate the effectiveness and rapid action of the drug in the treatment of dermatitis.
The price of Mometazon-Akrikhin in pharmacies
The price of Mometason-Akrikhin for a tube containing 15 g of cream can range from 205 rubles.
Mometazon-Akrikhin: prices in online pharmacies
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Drug name Price Pharmacy |
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Mometasone-Akrikhin 0.1% cream for external use 15 g 1 pc. RUB 180 Buy |
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Mometasone-Akrikhin cream for outside. approx. 0.1% tube 15g 195 RUB Buy |
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Mometasone-Akrikhin 0.1% cream for external use 30 g 1 pc. 313 r Buy |
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Mometasone-Akrikhin cream for outside. approx. 0.1% tube 30g 322 RUB Buy |
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
