Diphenhydramine - Instructions For Use, Indications, Doses, Analogues

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Diphenhydramine - Instructions For Use, Indications, Doses, Analogues
Diphenhydramine - Instructions For Use, Indications, Doses, Analogues

Video: Diphenhydramine - Instructions For Use, Indications, Doses, Analogues

Video: Diphenhydramine - Instructions For Use, Indications, Doses, Analogues
Video: Diphenhydramine Nursing Considerations, Side Effects, Mechanism of Action Pharmacology for Nurses 2024, September
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Diphenhydramine

Instructions for use:

  1. 1. Release form and composition
  2. 2. Indications for use
  3. 3. Contraindications
  4. 4. Method of application and dosage
  5. 5. Side effects
  6. 6. Special instructions
  7. 7. Drug interactions
  8. 8. Analogs
  9. 9. Terms and conditions of storage
  10. 10. Terms of dispensing from pharmacies

Prices in online pharmacies:

from 3 rubles.

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Diphenhydramine tablets
Diphenhydramine tablets

Diphenhydramine is an anti-allergic agent, blocker of H1 receptors.

Release form and composition

Dimedrol dosage forms:

  • Tablets: white, round flat-cylindrical shape with a chamfer (10 pcs. In a blister strip, in a cardboard box 1, 2, 3 or 5 packs; 10 pcs. In a non-cell contour packaging, in a paper bag 1 pack or in a cardboard box 1, 2 or 3 packs; 10 pcs. Or 20 pcs. In dark glass jars, in a cardboard box 1 can);
  • Solution for intravenous (intravenous) and intramuscular (intramuscular) administration: colorless transparent liquid in 1 ml ampoules (5 pcs. In a blister strip, in a cardboard box 1 or 2 packages; 10 pcs. In a cardboard box or 10 pieces in a blister strip, in a cardboard box 2 packs; 10 pieces in a blister, in a cardboard box 1 package).

Active substance content:

  • Tablets: diphenhydramine hydrochloride, 1 pc. - 50 mg;
  • Solution: diphenhydramine, in 1 ml - 10 mg.

Auxiliary components:

  • Tablets: water-soluble methylcellulose - 0.326 mg; lactose monohydrate (milk sugar) - 75 mg, colloidal silicon dioxide (aerosil) - 0.76 mg, corn starch - 23.154 mg, stearic acid - 0.76 mg;
  • Solution: water for injection.

Indications for use

  • Allergic reactions, including hay fever, urticaria, angioedema;
  • Hemorrhagic vasculitis;
  • Allergic conjunctivitis;
  • Serum sickness;
  • Chorea;
  • Vasomotor rhinitis;
  • Itchy dermatoses;
  • Sleep disorders, as monotherapy or in combination with sleeping pills;
  • Vomiting of pregnant women;
  • Air and sea sickness;
  • Meniere's syndrome;
  • Premedication.

Contraindications

  • Stenosing ulcer of the duodenum and / or stomach;
  • Bronchial asthma;
  • Closed-angle glaucoma;
  • Bladder neck stenosis;
  • Hypertrophy of the prostate;
  • Epilepsy;
  • Hypersensitivity to diphenhydramine.

With caution and according to strict indications, diphenhydramine is prescribed during pregnancy and during breastfeeding, only if the expected benefit to the mother outweighs the likely risk to the fetus or child.

Method of administration and dosage

  • Tablets: taken orally. Dosage for adult patients: as a sleeping pill - 50 mg at bedtime; treatment - 30-50 mg 1-3 times a day, for 10-15 days. For children, a single dose is: under the age of 1 year - 2-5 mg; from 2 to 5 years - 5-15 mg; from 6 to 12 years old - 15-30 mg;
  • Solution for intravenous and intramuscular administration: for adult patients intramuscular injections at a dose of 50 to 250 mg, intravenous drip - 20-50 mg. It is recommended to apply externally 1-2 times a day.

Side effects

The use of diphenhydramine can cause side effects:

  • Possibly: drowsiness, short numbness of the oral mucosa, decreased attention, general weakness; in children, the paradoxical development of insomnia, euphoria and irritability;
  • Rarely: headache, dizziness, impaired coordination of movements, nausea, dry mouth, photosensitivity, tremor, paresis of accommodation.

special instructions

The patient is advised to avoid exposure to sunlight during the period of use of the drug, it is necessary to stop drinking alcohol.

During pregnancy and breastfeeding, the drug should be used under close medical supervision.

It is prescribed with caution to patients engaged in potentially hazardous types of work, the performance of which requires quick psychomotor reactions and increased attention.

Drug interactions

The use of Diphenhydramine increases the activity of drugs that depress the central nervous system, enhances the effect of ethanol.

The combination with monoamine oxidase (MAO) inhibitors increases the anticholinergic activity of the drug.

An antagonistic reaction occurs against the background of joint administration with psychostimulants.

The simultaneous use of the drug reduces the emetic effect of apomorphine in the treatment of poisoning.

The drug increases the anticholinergic effects of drugs with anticholinergic activity.

Analogs

Dimedrol analogs are: Dimedrol-ROS, Dimedrol-UBF, Dimedrol-UVI, Dimedrol-Vial, Dimedrol Bufus, Dramina, Kalmaben.

Terms and conditions of storage

  • Tablets: store in a dry, dark place;
  • Solution: store in a dark place at temperatures up to 30 ° C.

Keep out of the reach of children.

The shelf life is 5 years.

Terms of dispensing from pharmacies

Dispensed by prescription.

Diphenhydramine: prices in online pharmacies

Drug name

Price

Pharmacy

Diphenhydramine 50 mg tablets 10 pcs.

RUB 3

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Diphenhydramine 50 mg tablets 20 pcs.

RUB 8

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Diphenhydramine (for injection) 10 mg / ml solution for intravenous and intramuscular administration 1 ml 10 pcs.

RUB 21

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Diphenhydramine (for injection) 10 mg / ml solution for intramuscular administration 1 ml 10 pcs.

RUB 23

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Diphenhydramine (for injection) 10 mg / ml solution for intravenous and intramuscular administration 1 ml 10 pcs.

RUB 24

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Diphenhydramine 50 mg tablets 20 pcs.

RUB 27

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Diphenhydramine (for injection) 10 mg / ml solution for intravenous and intramuscular administration 1 ml 10 pcs.

RUB 27

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Diphenhydramine solution for intravenous and intramuscular injection. 10mg / ml 1ml 10 pcs.

RUB 29

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Diphenhydramine solution in / m introduction 10 mg / ml amp. 1ml No. 10

35 RUB

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Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!

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