Guttasil
Instructions for use:
- 1. Release form and composition
- 2. Indications for use
- 3. Contraindications
- 4. Method of application and dosage
- 5. Side effects
- 6. Special instructions
- 7. Drug interactions
- 8. Analogs
- 9. Terms and conditions of storage
- 10. Terms of dispensing from pharmacies
Prices in online pharmacies:
from 125 rub.
Buy
Guttasil is a laxative of the triarylmethane group, which stimulates intestinal peristalsis.
Release form and composition
- drops for oral administration: colorless or light yellow transparent liquid (15 and 30 ml each in polyethylene bottles with dispensers or dropper stoppers, 1 bottle in a cardboard box);
- tablets: flat-cylindrical, round, almost white or white, with a chamfer and a score (10 pieces in blisters, in a cardboard box 1 blister with 5 mg tablets, 1 or 3 blisters with 7.5 mg tablets).
The active substance is sodium picosulfate monohydrate, its content in terms of sodium picosulfate is:
- 1 ml drops - 7.5 mg;
- 1 tablet - 5 or 7.5 mg.
Excipients of drops: water for injection, sodium methyl parahydroxybenzoate, sorbitol, 1M hydrochloric acid solution.
Excipients of tablets: colloidal silicon dioxide, corn starch, magnesium stearate, pregelatinized starch, lactose monohydrate.
Indications for use
- treatment of constipation caused by a violation of the diet or intestinal dysbiosis;
- treating constipation caused by taking certain medications;
- treatment of constipation caused by atony or hypotension of the colon, including after childbirth, during breastfeeding, after surgical interventions, in old age;
- treating constipation due to gallbladder disease or irritable bowel syndrome.
Also, the drug is used to regulate stool in conditions requiring relief of defecation (softening of the consistency of feces), including anal fissures, proctitis and hemorrhoids, preparation for X-ray and instrumental studies or surgical interventions.
Contraindications
Absolute:
- obstructive bowel disease;
- intestinal obstruction;
- acute abdominal pain (including appendicitis), acute diseases of the abdominal organs, acute inflammatory bowel disease, which may be accompanied by nausea and vomiting, fever;
- severe dehydration;
- I trimester of pregnancy;
- lactation period (or you should stop breastfeeding);
- lactose intolerance, lactase deficiency, glucose-galactose malabsorption - for tablets;
- hereditary fructose intolerance - for drops;
- children under 10 years old - for 7.5 mg tablets, up to 4 years - for 5 mg tablets;
- hypersensitivity to any component of the drug.
Relative (caution should be exercised in the following conditions / diseases):
- high levels of magnesium in the blood;
- hypokalemia;
- asthenia;
- elderly age;
- II – III trimesters of pregnancy (only if the benefit to the mother outweighs the harm to the fetus).
Method of administration and dosage
Guttasil should be taken orally, preferably at night (so that the stool is the next morning).
For children, the drug in the form of drops can be added to food.
To eliminate constipation in cancer patients receiving high doses of opioids, Guttasil is used as directed by the attending physician.
It is recommended to start treatment with a minimum dose, gradually increasing it until the desired effect is achieved.
Oral drops
Recommended doses:
- adults and adolescents from 10 years old - 5-10 mg (13-27 drops);
- children 4-10 years old - 2.5-5 mg (7-13 drops);
- children under 4 years old - 0.25 mg / kg (at the rate of 2 drops for every 3 kg of body weight).
The duration of treatment is set individually. In adults, it should not exceed 10 days. It is advisable for children to limit the course of therapy to three days.
Pills
Recommended doses:
- adults and adolescents from 10 years old - 5–10 mg 1 time per day, in some cases it is allowed to increase the dose to 15 mg;
- children 4-10 years old - 2.5-5 mg.
The duration of treatment is set individually. In adults, it should not exceed 10 days. It is advisable for children to limit the course of therapy to three days.
Side effects
With a short-term intake of Guttasil, side effects are extremely rare.
With long-term treatment, especially in the case of taking high doses, the following undesirable effects are possible:
- from the digestive system: pain in the stomach and anus, abdominal cramps and pain, nausea, flatulence, vomiting, increased intestinal motility, diarrhea and other dyspeptic phenomena (these reactions disappear after a decrease in the dose of the drug);
- on the part of the water-electrolyte balance: dehydration, loss of electrolytes (including sodium and potassium);
- from the central nervous system: drowsiness, increased fatigue, headache, fainting, convulsions;
- from the immune system: hypersensitivity reactions, including angioedema;
- on the part of the skin: skin rashes, itching, urticaria.
In case of an overdose, the following symptoms are possible: diarrhea, abdominal cramps, ischemia of the mucous membrane of the large intestine, serious violations of the water and electrolyte balance, convulsions. Long-term overdose is fraught with the development of chronic abdominal pain and diarrhea, hypokalemia and muscle weakness, secondary hyperaldosteronism, metabolic alkalosis, nephrolithiasis, and kidney damage. When taking a dose exceeding the recommended one, you should induce vomiting, make a gastric lavage and take an enterosorbent (for example, activated carbon). Further treatment is symptomatic (use of antispasmodic drugs, correction of violations of water and electrolyte balance).
special instructions
Like other laxatives, Guttasil is not intended for daily or long-term use. An adult should not take the drug for more than 10 days without consulting a doctor. If it becomes necessary to drink a laxative every day, the patient should undergo an appropriate examination to establish the cause of constipation. Long-term use of a laxative can lead to hypokalemia, electrolyte imbalance and loss of body fluids, as well as cause "rebound" constipation and the development of addiction.
Special clinical studies on the effect of sodium picosulfate on the reaction rate and the ability to concentrate have not been conducted. However, it should be borne in mind that with a vasovagal reaction (with intestinal spasm), dizziness and even fainting may occur. In this case, patients should refrain from potentially hazardous activities, including driving vehicles and operating complex mechanisms.
Drug interactions
Guttasil can cause electrolyte imbalances, which may lead to an increase in sensitivity to cardiac glycosides.
Glucocorticosteroids and diuretics, when administered simultaneously, can increase the severity of hypokalemia caused by sodium picosulfate used in high doses.
Antibiotics reduce the laxative effect of the drug.
Analogs
Analogs of Guttasil are: Laxigal, Guttalaks, Slabilen, Regulax Picosulfate.
Terms and conditions of storage
Keep out of reach of children at temperatures up to 25 ° C.
Shelf life:
- drops - 3 years;
- tablets - 2 years.
Terms of dispensing from pharmacies
Available without a prescription.
Guttasil: prices in online pharmacies
|
Drug name Price Pharmacy |
|
Guttasil 7.5 mg / ml oral drops 15 ml 1 pc. 125 RUB Buy |
|
Guttasil drops for internal approx. 7.5mg / ml vial 15ml 139 RUB Buy |
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Guttasil tab. 7.5 mg 30 pcs. (blister) 220 RUB Buy |
|
Guttasil 7.5 mg tablets 30 pcs. 223 r Buy |
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Guttasil 7.5 mg / ml oral drops 30 ml 1 pc. 229 r Buy |
|
Guttasil drops for internal approx. 7.5mg / ml 30ml 285 r Buy |
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
