Betaver
Betaver: instructions for use and reviews
- 1. Release form and composition
- 2. Pharmacological properties
- 3. Indications for use
- 4. Contraindications
- 5. Method of application and dosage
- 6. Side effects
- 7. Overdose
- 8. Special instructions
- 9. Application during pregnancy and lactation
- 10. Use in childhood
- 11. Drug interactions
- 12. Analogs
- 13. Terms and conditions of storage
- 14. Terms of dispensing from pharmacies
- 15. Reviews
- 16. Price in pharmacies
Latin name: Betaver
ATX code: N07CA01
Active ingredient: betahistine (Betahistine)
Manufacturer: JSC "Veropharm" (Russia)
Description and photo update: 2019-26-08
Prices in pharmacies: from 100 rubles.
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Betaver is a histamine-like drug used for pathologies of the vestibular apparatus. Improves the microcirculation of the labyrinth.
Release form and composition
Betaver is available in tablet form:
- Betaver 8 mg: flat-cylindrical, white or almost white, with a chamfer (10 pcs. In blisters, 3 packs in a cardboard box; 30 pcs. In orange glass jars, 1 can in a cardboard box);
- Betaver 16 mg: flat-cylindrical, white or almost white, with a line and a chamfer (10 pcs. In blisters, 3 packs in a cardboard box; 30 pcs. In orange glass cans, 1 can in a cardboard box);
- Betaver 24 mg: flat-cylindrical, white or almost white, with a line and a chamfer (10 pcs. In blisters, in a cardboard box 2, 3 or 6 packs; 20 or 30 pcs. In orange glass jars, in a cardboard box 1 bank).
Composition of 1 tablet:
- active substance: betahistine dihydrochloride - 8 mg, 16 mg or 24 mg;
- auxiliary components: povidone, colloidal silicon dioxide, milk sugar, talc, microcrystalline cellulose, sodium carboxymethyl starch, corn starch.
Pharmacological properties
Pharmacodynamics
Betahistine acts primarily on histamine H 1 and H 3 receptors localized in the vestibular nuclei of the central nervous system (CNS) and the inner ear. The drug helps to improve the permeability of the capillaries of the inner ear and microcirculation processes in them, and also normalizes the pressure of endolymph in the cochlea and labyrinth through a direct agonistic effect on the H 1 receptors located in the vessels of the inner ear, as well as an indirect effect on the H 3 receptors. At the same time, the active ingredient of the drug increases blood flow in the basilar artery.
Betahistine is characterized by a pronounced central effect, being an inhibitor of H 3 receptors, the localization of which is the nuclei of the vestibular nerve. The drug improves the conductivity in the neurons of the vestibular nuclei at the level of the brain stem. The above properties provide a therapeutic effect, which is expressed in the normalization of hearing in case of deterioration, a decrease in tinnitus, a decrease in the intensity and frequency of dizziness. Betahistine enhances the tone of the gastrointestinal tract (GIT) and bronchial smooth muscles, and can also activate the secretion of gastric juice.
Pharmacokinetics
Betahistine is rapidly absorbed from the gastrointestinal tract and slightly binds to blood plasma proteins. Its maximum content in blood plasma is determined 3 hours after ingestion. The half-life is 3-4 hours. Betahistine is almost 100% excreted in the urine as a metabolite (2-peridylacetic acid) for 1 day.
Indications for use
- Meniere's syndrome and disease;
- prevention and treatment of vestibular dizziness of various etiologies;
- syndromes in which there is tinnitus, nausea and vomiting, headache, dizziness, and progressive hearing loss.
Contraindications
Absolute:
- the period of pregnancy and lactation (since there is not enough data on the safety and effectiveness of the drug in pregnant and lactating women);
- hypersensitivity to the main or auxiliary ingredients of the drug.
Relative (Betaver is used with caution):
- bronchial asthma;
- pheochromocytoma;
- peptic ulcer of the duodenum and stomach (including a history);
- children's age (for tablets at a dosage of 24 mg).
Instructions for the use of Betaver: method and dosage
Betaver tablets are intended for oral administration.
The drug is taken after meals at 8-16 mg (1-2 tablets of Betaver 8 mg or 1/2-1 tablets of Betaver 16 mg) three times a day or 24 mg (1 tablet of Betaver 24 mg) twice a day.
The patient's condition improves already at the beginning of treatment, however, a stable therapeutic effect is achieved during the first two weeks of taking Betaver and increases with further use.
The duration of the course of treatment is determined by the attending physician. As a rule, the drug is used for a long time.
Side effects
During the period of therapy, side effects from the gastrointestinal tract (a feeling of heaviness in the epigastric region, mild nausea) may occur, and in very rare cases, allergic reactions occur (skin rash, urticaria, itching, angioedema).
Overdose
When taking Betaver at a dose of more than 640 mg, symptoms such as nausea, vomiting, and seizures may occur. As therapeutic measures, gastric lavage, intake of activated charcoal are recommended, symptomatic therapy is carried out if necessary.
special instructions
Patients with bronchial asthma, pheochromocytoma and duodenal ulcer and stomach ulcer should be under the supervision of a physician throughout the course of treatment.
The use of Betaver with or after meals helps to reduce the likelihood of dyspeptic disorders.
Influence on the ability to drive vehicles and complex mechanisms
According to the instructions, Betaver does not have a sedative effect and does not affect the patient's ability to drive cars and other vehicles or work with potentially dangerous machinery.
Application during pregnancy and lactation
Betaver is not prescribed during pregnancy and during breastfeeding, since there is not enough data on the effectiveness and safety of the drug in this category of patients.
Pediatric use
In pediatric practice, Betaver tablets at a dosage of 24 mg are recommended to be used with caution.
Drug interactions
When taken together with antihistamines, the effectiveness of betahistine decreases.
Analogs
Betaver analogs are: Betagistin, Asniton, Betaserk, Betacsentrin, Vasoserk, Vestibo, Vertran, Westinorm-Neo, Vestikap, Tagista, etc.
Terms and conditions of storage
Store in a dry place, protected from light, at a temperature not exceeding 25 ° C. Keep out of the reach of children.
Shelf life is 4 years.
Terms of dispensing from pharmacies
Dispensed by prescription.
Reviews about Betaver
Numerous positive reviews about Betaver confirm that it is effective for severe hearing impairment, nausea / vomiting, headache, dizziness, and tinnitus. At the same time, there are practically no complaints of side effects. Patients note as an advantage that Betaver can be taken for a long time. It is indicated that, being a generic drug of a well-known brand, it has the same efficacy as the original, but costs much less. Therefore, when comparing analogs, they often make a choice in its favor.
The price of Betaver in pharmacies
The approximate price for Betaver, depending on the dosage and the number of tablets in the package:
- tablets 8 mg: for 30 pcs. in the package - 110‒169 rubles;
- tablets 16 mg: for 30 pcs. in the package - 118‒246 rubles;
- tablets 24 mg: for 20 pcs. in the package - 191‒253 rubles; for 30 pcs. in the package - 258-340 rubles; for 60 pcs. in the package - 386-573 rubles.
Betaver: prices in online pharmacies
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Drug name Price Pharmacy |
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Betaver 24 mg tablets 20 pcs. RUB 100 Buy |
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Betaver 16 mg tablets 30 pcs. RUB 138 Buy |
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Betaver 24 mg tablets 30 pcs. 227 r Buy |
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Betaver tablets 16mg 30 pcs. 279 r Buy |
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Betaver 24mg tablets 30 pcs. 296 r Buy |
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Betaver 24 mg tablets 60 pcs. 310 RUB Buy |
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Betaver tablets 24mg 60 pcs. 472 r Buy |
Maria Kulkes Medical journalist About the author
Education: First Moscow State Medical University named after I. M. Sechenov, specialty "General Medicine".
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
