Tranexam
Instructions for use:
- 1. Pharmacological action
- 2. Instructions for use
- 3. Methods of application
- 4. Side effects
- 5. Contraindications
- 6. Interaction with other means
- 7. Release form and storage conditions
Prices in online pharmacies:
from 217 rub.
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Tranexam is a drug belonging to the group of hemostatic drugs.
Pharmacological action of Tranexam
Tranexam is a fibrinolysis inhibitor. Has antifibrinolytic effect and prevents the conversion of plasminogen to plasmin. In the instructions for Tranexam it is noted that this drug has a good systemic and local hemostatic effect. Its use is especially effective for bleeding accompanied by an increase in the content of fibrinolysin in the blood, for example, with platelet pathology or menorrhagia. In addition, according to reviews, Tranexam is able to have anti-inflammatory, antitumor and anti-allergic effects.
This drug is well and fairly evenly distributed in all tissues of the body, is able to penetrate the blood-brain and placental barrier. After taking Tranexam in tablets, its maximum concentration in the blood is observed after three hours. The therapeutic concentration in the tissues lasts about 17 hours.
In case of impaired renal function, accumulation of tranexamic acid in the patient's body may occur.
Instructions for use
As a hemostatic drug, Tranexam is used in the following cases:
- For the prevention of the development of bleeding caused by an increased systemic content of fibrinolysin, as well as for their treatment (bleeding during pregnancy, liver disease, malignant neoplasms of the prostate and pancreas, manual separation of the placenta, postpartum bleeding, operations and the early postoperative period, chorionic detachment, leukemia, hemophilia);
- For the prevention and treatment of bleeding caused by local activation of fibrinolysin (tooth extraction in patients suffering from hemorrhagic diathesis, hematuria, gastrointestinal bleeding, nose and uterine bleeding).
According to the instructions, Tranexam can also be used as an antiallergic agent for the treatment of allergic dermatitis, urticaria, eczema. Also, Tranexam can be used in the complex therapy of angioedema (Quincke's edema).
According to reviews, Tranexam, due to its anti-inflammatory properties, is a fairly effective drug in the treatment of stomatitis, laryngitis, pharyngitis and tonsillitis.
Ways of using Tranexam
Tranexam tablets are taken:
- With repeated nosebleeds three times a day, 1.0 g for 7 days;
- With uterine bleeding - 1.0 g every six hours for three days;
- After tooth extraction in patients with hemorrhagic diathesis for the prevention of secondary bleeding, Tranexam tablets are prescribed at the rate of 25 mg / kg 4 times a day for a week;
- For the treatment of hereditary angioedema, the drug is prescribed in courses or constantly, 1.0 g twice a day;
- In the postoperative period, 1.5 g three times a day for 10 - 14 days.
Tranexam for intravenous drip or jet injection is usually used to stop massive bleeding, as well as bleeding that occurs during surgery. Before tooth extraction, the drug is also administered intravenously to patients with impaired blood clotting, and after extraction, Tranexam is prescribed in tablets.
Side effects of Tranexam
In the instructions for Tranexam, it is noted that the use of this drug can lead to the development of the following adverse reactions:
- Decreased appetite, nausea, vomiting, heartburn, diarrhea;
- Drowsiness, disturbances in color perception and vision, weakness, dizziness;
- Thromboembolism, thrombosis, chest pain, tachycardia;
- Urticaria, skin rash, itching.
According to reviews, Tranexam, when administered quickly, can lead to the development of arterial hypotension.
Contraindications
According to the instructions, Tranexam is contraindicated in the following cases:
- Subarachnoid bleeding;
- Individual intolerance to the drug.
With extreme caution, Tranexam should be used in the treatment of patients with myocardial infarction, deep vein or cerebrovascular thrombosis, as well as renal failure.
The use of Tranexam during pregnancy is permissible only in cases where its benefits for the mother's body significantly exceed the possible risk of negative effects on the fetus.
Interaction of Tranexam with other drugs
Tranexam in the form of a solution for intravenous administration should not be mixed with blood products, hypertensive drugs, urokinase, penicillin, diazepam, tetracyclines. With the simultaneous appointment of Tranexam with other hemostatic drugs, a sharp increase in the activity of the thrombus formation process is possible.
Release form and storage conditions
Tranexam is available in the form of film-coated tablets and ampoule solution intended for intravenous administration. The drug is stored in a cool, dry and dark place out of the reach of children. Shelf life of Tranexam is three years.
Tranexam: prices in online pharmacies
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Drug name Price Pharmacy |
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Tranexam 250 mg film-coated tablets 10 pcs. 217 r Buy |
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Tranexam solution for intravenous injection 100mg / ml amp. 5ml 10 pcs 1838 RUB Buy |
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Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
