Synthomycin - Instructions For Use, Indications, Doses

2024 Author: Rachel Wainwright | [email protected]. Last modified: 2023-12-15 07:39

Synthomycin

Instructions for use:

1. 1. Release form and composition
2. 2. Indications for use
3. 3. Contraindications
4. 4. Method of application and dosage
5. 5. Side effects
6. 6. Special instructions
7. 7. Drug interactions
8. 8. Terms and conditions of storage

Prices in online pharmacies:

from 32 rubles.

Buy

Synthomycin is a bacteriostatic drug. Broad-spectrum antibiotic.

Release form and composition

Synthomycin is available in the following dosage forms:

• liniment: white or white with a yellowish tinge, with a specific odor (25 g or 35 g in aluminum tubes, 1 tube in a cardboard box; 25 g, 40 g, 50 g, 800 g or 1800 g in dark glass jars, in cardboard packaging 1 can);
• vaginal suppositories: white or white with a yellowish or creamy tinge, torpedo-shaped, without inclusions in the longitudinal section (5 suppositories in blisters, 2 packs in a cardboard box).

Composition for 1 g of liniment:

• active substance: synthomycin (chloramphenicol) - 100 mg;
• auxiliary components: emulsifier No. 1, castor oil, ethanol, sorbic acid, sodium carmellose, water.

Composition for 1 suppository:

• active substance: synthomycin (chloramphenicol) - 250 mg;
• auxiliary components: witepsol (solid fat).

Indications for use

Liniment

• 2nd and 3rd degree burns;
• trophic ulcers that do not heal for a long time;
• infected wounds in the second phase of the wound process (when there are no necrotic tissues and pus).

Vaginal suppositories

• vaginitis, cervicitis and other bacterial infections of the pelvic organs caused by microorganisms sensitive to syntomycin;
• prevention of purulent-inflammatory infections in gynecology (before and after the procedure for installing an intrauterine device, before gynecological operations and abortion).

Contraindications

• oppression of hematopoiesis in the bone marrow;
• insufficiency of kidney and / or liver function;
• acute intermittent porphyria;
• fungal diseases of the skin or vagina;
• deficiency of glucose-6-phosphate dehydrogenase;
• infected wounds in the first phase of the wound process (for Syntomycin in the form of liniment);
• the period of pregnancy and lactation (for Syntomycin in the form of liniment);
• children's age up to four weeks (for Syntomycin in the form of liniment);
• childhood and adolescence up to puberty (for Syntomycin in the form of suppositories);
• increased individual sensitivity to any component of the drug.

Liniment syntomycin is prescribed with caution in early childhood and in patients who have previously received treatment with cytostatic drugs or have undergone radiation therapy.

Method of administration and dosage

Liniment

Liniment synthomycin is intended for external use. The drug is applied to the wound surface after preliminary surgical treatment of burns and wounds. A sterile gauze bandage is applied on top. Liniment can be applied to the dressing and then applied to the wound. The gauze dressings are changed once every 1-3 days, depending on the speed of wound healing.

After surgical treatment, fistulous passages and purulent wounds are loosely filled with gauze turundas or tampons with Syntomycin.

Vaginal suppositories

Synthomycin in the form of vaginal suppositories is intended for intravaginal use. The drug is administered 2-3 times a day, 1 suppository. The procedure is performed with the patient lying on his back. The suppository is inserted deep into the vagina.

The maximum daily dose is 4 suppositories. For girls who have reached puberty, the dose of Syntomycin is 1 suppository 1–2 times a day.

The duration of therapy varies on average from 8 to 10 days.

Side effects

Allergic reactions (angioedema, skin rash) may occur during the use of Syntomycin. In rare cases, suppression of hematopoiesis is possible (aplastic anemia, reticulocytopenia, agranulocytosis, leukopenia, thrombocytopenia, granulocytopenia, erythropenia).

special instructions

During therapy, it is necessary to control the peripheral blood picture.

During treatment with Synthomycin, especially when liniment is applied to large areas, it is not recommended to use ethanol, since disulfiram-like reactions may occur (vomiting, nausea, convulsions, tachycardia, redness of the skin, reflex cough).

Drug interactions

Synthomycin can weaken the action of clindamycin, erythromycin and lincomycin.

Chloramphenicol reduces the antibacterial effect of cephalosporins and penicillins.

Terms and conditions of storage

Keep out of reach of children at room temperature (no more than 20-25 ° C). Shelf life of liniment - 2 years, suppositories - 3 years.

Synthomycin: prices in online pharmacies

Drug name Price Pharmacy

Synthomycin 250 mg vaginal suppositories 10 pcs. 32 RUB Buy

Synthomycin 10% liniment 25 g 1 pc. RUB 37 Buy

Synthomycin 10% liniment 25 g 1 pc. RUB 38 Buy

Synthomycin 10% liniment 25 g 1 pc. 52 RUB Buy

Synthomycin 250 mg vaginal suppositories 10 pcs. RUB 56 Buy

Synthomycin 250 mg vaginal suppositories 10 pcs. RUB 69 Buy

Synthomycin liniment 10% 25g RUB 71 Buy

Synthomycin supp. vag. 250mg No. 10 RUB 76 Buy

See all offers from pharmacies

Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!