Ksefokam
Instructions for use:
- 1. Pharmacological action
- 2. Indications for use
- 3. Contraindications
- 4. Instructions for use
- 5. Side effects
- 6. Additional information
Prices in online pharmacies:
from 199 rub.
Buy
Ksefokam is an anti-inflammatory and analgesic drug used to relieve pain and symptomatic treatment of rheumatic diseases.
pharmachologic effect
The active ingredient in Ksefokam is lornoxicam.
The anti-inflammatory effect of the drug is due to the ability of lornoxicam to inhibit the synthesis of prostaglandins, which are one of the regulators of biochemical processes in the body, as well as to suppress the release of free radicals that are involved in provoking inflammatory processes.
After oral administration of Ksefokam, the maximum concentration of the drug in the blood can be observed after 1-2 hours. Ksefokam injections act faster - the maximum concentration is noted after 15 minutes.
About 1/3 of the metabolites of larnoxicam are excreted in the urine, and 2/3 in the bile. The half-life of Ksefokam is 4 hours, it does not depend on the concentration level of the drug. Ksefokam, reviews confirm, does not cause drug dependence and addiction.
Indications for use of Ksefokam
Ksefokam tablets are prescribed for:
- moderate and severe pain of various origins: myalgia, pain in the spine, cancer;
- rheumatic diseases for the symptomatic treatment of inflammation and pain.
Ksefokam injections are advisable for short-term treatment of postoperative pain and pain caused by an acute attack of sciatica (pain in the leg as a result of damage to the sciatic nerve) or lumbago (lumbago in the lower back).
Contraindications
According to the instructions, Ksefokam is not prescribed for:
- blood clotting disorders;
- nonspecific ulcerative colitis, stomach or duodenal ulcers in the acute stage;
- severe kidney disease;
- significant violations of hepatic functions;
- hemorrhagic stroke;
- dehydration, hypovolemia (decrease in blood volume);
- bronchial asthma;
- hearing loss;
- heart failure;
- deficiency of glucose-6-phosphate dehydrogenase.
The use of Ksefokam is contraindicated in patients under 18 years of age, pregnant women and patients who are breastfeeding.
Instructions for use Ksefokam
For oral administration, Ksefokam tablets containing 4 mg or 8 mg of lornoxicam are intended.
With moderate or severe pain, 16 mg of the drug is prescribed per day, divided into two doses. On the first day of treatment, if necessary, it is possible to use an additional 16 mg.
For rheumatic diseases, as well as for maintenance therapy, the Ksefokam drug instruction recommends taking 4-8 mg twice a day, depending on the patient's well-being.
Ksefokam injections can be administered intravenously (at least 15 seconds) and intramuscularly (at least 5 seconds). To prepare a solution for injection, take 8 mg of dry powder and dilute in 2 ml of solvent. Ksefokam injections are used for acute pain syndrome: the recommended dose is 8 mg, with an insufficient analgesic effect, 8 mg of the drug is re-administered. Supportive therapy involves the use of Ksefokam 2 times a day, 8 mg.
For patients with renal or hepatic insufficiency, diseases of the digestive tract, with a body weight of less than 50 kg, dose adjustment is not required.
Side effects
Reviews and instructions include undesirable effects of Ksefokam:
- headache, insomnia, dizziness, drowsiness, agitation, migraine, meningitis, hallucinations, neuritis (inflammation of the peripheral nerves);
- conjunctivitis, visual impairment, hearing loss, tinnitus;
- sweating, fluctuations in body weight, chills;
- palpitations, peripheral edema, increased blood pressure;
- abdominal pain, flatulence, vomiting, nausea, dysphagia (difficulty swallowing);
- intestinal and rectal bleeding, peptic ulcers, hepatitis, colitis (inflammation of the large intestine), pancreatitis (inflammation of the pancreas), glossitis (inflammation of the tongue), stomatitis, dry mouth, changes in liver function;
- renal failure, increased urine production, glomerulonephritis (inflammation of tiny filters in the kidneys, called glomeruli), crystalluria (appearance of salt crystals in the urine), nephrotic syndrome (a condition with kidney damage), urinary dysfunction;
- skin rash, allergic rhinitis, shortness of breath, bronchospasm, esfoliative dermatitis (inflammation of the skin surface, expressed in redness and flaking), angiitis (inflammation of the vessels of the subcutaneous tissue and the walls of the skin vessels).
In the reviews about Xefocam, you can find information about the negative effect of the drug on the ability of women to become pregnant, which is explained by the action of lornoxicam, aimed at inhibiting the synthesis of prostaglandins.
Additional Information
The instruction recommends storing Ksefokam in a dark and dry place where the temperature does not rise above 25 ° C.
Ksefokam tablets and powder for solution preparation, subject to storage conditions, will be usable for 5 years. Ready-to-use Xefocam solution should be used throughout the day, after 24 hours it is considered unusable.
Ksefokam: prices in online pharmacies
Drug name Price Pharmacy |
Ksefokam 8 mg film-coated tablets 10 pcs. 199 RUB Buy |
Ksefokam rapid 8 mg film-coated tablets 12 pcs. RUB 200 Buy |
Ksefokam tablets p.p. 8mg 10 pcs. 214 r Buy |
Ksefokam Rapid tablets p.o. 8mg 12 pcs. 326 RUB Buy |
Ksefokam 8 mg film-coated tablets 30 pcs. 413 r Buy |
Ksefokam tablets p.p. 8mg 30 pcs. 469 r Buy |
Ksefokam 8 mg lyophilisate for preparation of a solution for intravenous and intramuscular administration 5 pcs. RUB 525 Buy |
Ksefokam lyof. for prigot. solution for intravenous and intramuscular injection. 8mg 5 pcs. 715 RUB Buy |
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Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!