Polyvalent Dysentery Bacteriophage - Instructions For Use, Indications, Doses

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Polyvalent Dysentery Bacteriophage - Instructions For Use, Indications, Doses
Polyvalent Dysentery Bacteriophage - Instructions For Use, Indications, Doses

Video: Polyvalent Dysentery Bacteriophage - Instructions For Use, Indications, Doses

Video: Polyvalent Dysentery Bacteriophage - Instructions For Use, Indications, Doses
Video: Bacteriophages -- Adam Pettigrew, MD 2024, November
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Dysentery polyvalent bacteriophage

Instructions for use:

  1. 1. Release form and composition
  2. 2. Indications for use
  3. 3. Contraindications
  4. 4. Method of application and dosage
  5. 5. Side effects
  6. 6. Special instructions
  7. 7. Drug interactions
  8. 8. Terms and conditions of storage

Prices in online pharmacies:

from 568 rub.

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Tablets Bacteriophage dysentery polyvalent
Tablets Bacteriophage dysentery polyvalent

Polyvalent dysentery bacteriophage is a drug of antibacterial and immunostimulating action. It causes specific lysis of pathogens of dysentery of bacterial origin.

Release form and composition

Polyvalent dysenteric bacteriophage is produced in the following forms:

  • tablets: round, biconvex, 7 mm in diameter, white with a light brown tint, with a smooth surface (10 pieces in blisters, 5 packs in a cardboard box; 50 pieces in glass bottles, 10 bottles in a cardboard box);
  • solution for oral administration and rectal administration: transparent, yellow (with varying degrees of intensity), sometimes with a greenish tint (20 ml in glass vials, in a cardboard box 4 or 10 bottles; 100 ml in glass bottles, in a cardboard box 1 bottle).

Composition of 1 tablet:

  • active substance: lyophilized concentrate of phagolysate filtrate of bacterial dysentery pathogens (Shigella sonnei and Shigella flexneri 1, 2, 3, 4 and 6 serovariants) - 72 mg;
  • auxiliary components: calcium gluconate monohydrate, purified medical talc, pectin, calcium stearate monohydrate, dextrose monohydrate.

Composition of 20 ml solution:

  • active substance: a mixture of sterile filtrates of phagolysates of bacterial dysentery pathogens (Shigella sonnei and Shigella flexneri 1, 2, 3, 4 and 6 serovariants) - 20 ml;
  • auxiliary components: preservative (8-hydroxyquinoline sulfate monohydrate or 8-hydroxyquinoline sulfate).

Indications for use

Polyvalent dysentery bacteriophage is used for the prevention and treatment of bacterial dysentery caused by Shigella sonnei and Shigella flexneri 1, 2, 3, 4 and 6 serovars.

For effective phage therapy, it is important to first determine the phage sensitivity of the pathogen and start treatment as early as possible.

Contraindications

Pills

  • period of pregnancy;
  • period of breastfeeding;
  • children's age up to 12 months;
  • increased individual sensitivity to components.

Solution for oral administration and rectal administration

A contraindication to the use of the solution is hypersensitivity to the components of the drug.

Method of administration and dosage

Pills

Polyvalent dysentery bacteriophage in the form of tablets is taken orally 1 hour before meals. Frequency rate of application - 3 times a day. Treatment begins from the first day of the disease and continues for 7-10 days.

Recommended single doses:

  • children aged 1-3 years - 1 tablet;
  • children aged 3–8 years old - 1–2 tablets;
  • children over 8 years old and adults - 2-3 tablets.

Solution for oral administration and rectal administration

Polyvalent dysentery bacteriophage in the form of a solution is taken orally 1 hour before meals or is administered rectally. The frequency of administration when taken orally is 3 times a day. Treatment begins from the first day of the disease and continues for 7-10 days.

Recommended single doses for oral administration:

  • children aged 0-6 months - 5 ml;
  • children aged 6-12 months - 10-15 ml;
  • children aged 1–3 years - 15–20 ml;
  • children aged 3–8 years - 20–30 ml;
  • children over 8 years old and adults - 30-40 ml.

Recommended doses for rectal administration:

  • children aged 0-6 months - 10 ml;
  • children aged 6-12 months - 20 ml;
  • children aged 1–3 years - 20–30 ml;
  • children aged 3–8 years - 30–40 ml;
  • children over 8 years old and adults - 50-60 ml.

In case of dysentery with mild colitis syndrome, as well as during the patient's recovery, it is recommended to combine taking tablets (2 times a day) with rectal administration in the form of an enema of liquid bacteriophage in a single dose for adults (1 time per day). Before rectal administration, it is necessary to empty the intestines.

For the prevention of polyvalent dysentery bacteriophage, it is recommended to use it during the period of group diseases in families and organized groups. The drug is taken daily once in a dose according to age. The duration of the preventive course is determined by the conditions of the epidemiological situation.

Side effects

The side effects of the drug have not been established.

special instructions

Polyvalent dysenteric bacteriophage should not be used in the absence of labeling on the packaging and turbidity of the solution (for a liquid bacteriophage).

In the nutrient medium contained in the preparation, bacteria from the environment can multiply, which causes the solution to become cloudy, therefore, when opening the bottle, the following rules must be observed:

  • wash your hands thoroughly;
  • treat the bottle cap with any alcohol-containing solution;
  • carefully remove the cap without opening the plugs;
  • do not put the cork from the bottle with the inside on the table or other surfaces;
  • do not leave the bottle with the solution open;
  • store the opened bottle in the refrigerator.

When using the drug in small doses (2–8 drops), the solution should be taken with a sterile syringe of 0.5–1 ml volume.

A liquid bacteriophage from an opened bottle can be used throughout the shelf life, if there is no turbidity, the storage conditions and rules for using the solution are strictly observed.

The drug does not affect the patient's ability to perform work associated with increased concentration and psychomotor reaction speed.

Drug interactions

Polyvalent dysentery bacteriophage can be used simultaneously with other drugs, including antibiotics.

Terms and conditions of storage

Store in a dry place protected from light at a temperature of 2-8 ° C. Keep out of the reach of children.

Shelf life is 2 years.

Polyvalent dysentery bacteriophage: prices in online pharmacies

Drug name

Price

Pharmacy

Bacteriophage dysentery polyvalent solution for oral administration or for rectal administration 20 ml 4 pcs.

568 r

Buy

Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!

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