Tobradex
Instructions for use:
- 1. Release form and composition
- 2. Indications for use
- 3. Contraindications
- 4. Method of application and dosage
- 5. Side effects
- 6. Special instructions
- 7. Drug interactions
- 8. Analogs
- 9. Terms and conditions of storage
- 10. Terms of dispensing from pharmacies
Prices in online pharmacies:
from 305 rubles.
Buy
Tobradex is a combined local preparation with anti-inflammatory and antibacterial action, used in ophthalmology.
Release form and composition
Dosage forms of Tobradex:
- eye drops: suspension from almost white to white (5 ml in plastic dropper bottles Drop Tainer, in a cardboard box 1 dropper bottle);
- eye ointment: homogeneous, almost white or white (in aluminum tubes of 3.5 g, in a cardboard box 1 tube).
Active ingredients in 1 ml drops and 1000 mg ointment:
- tobramycin - 3 mg;
- dexamethasone - 1 mg.
Auxiliary components:
- drops (1 ml): hydroxyethyl cellulose (hyetellose) - 2.5 mg; benzalkonium chloride - 0.1 mg (in the form of a solution); edetate disodium - 0.1 mg; sodium chloride - 3 mg; tyloxapol - 0.5 mg; anhydrous sodium sulfate - 12 mg; sulfuric acid and / or sodium hydroxide - to adjust the pH; purified water - up to 1 ml;
- ointment: liquid paraffin (mineral oil), chlorobutanol (anhydrous chlorobutanol), white petrolatum.
Indications for use
- inflammatory diseases of the eyes and their appendages, which are caused by pathogens sensitive to the active substances of Tobradex, including keratoconjunctivitis, blepharitis, conjunctivitis, keratitis, blepharoconjunctivitis, iridocyclitis (treatment);
- inflammation in the postoperative period after cataract extraction (treatment and prevention).
Contraindications
- fungal / purulent eye diseases;
- mycobacterial eye infections;
- viral eye diseases, including keratitis caused by Herpes simplex, chickenpox;
- conditions after removal of a corneal foreign body;
- lactation period;
- age up to 12 years (drops) or 18 years (ointment);
- individual intolerance to the components of the drug.
For pregnant women, Tobradex is prescribed only in cases where the expected benefit is higher than the possible harm (due to the lack of necessary clinical data to assess its effectiveness / safety).
Method of administration and dosage
Tobradex is applied topically (in the conjunctival sac).
Eye drops
The recommended dosage regimen: 1-2 drops every 4-6 hours.
In the first 2 days of therapy, the frequency of use can be increased (every 2 hours), then gradually, as the severity of the inflammatory process decreases, the frequency is reduced to standard.
In the treatment of an acute severe infectious process, the following dosing regimen is shown (single dose - 1-2 drops):
- until the severity of the condition decreases: every 60 minutes;
- for 3 days: every 2 hours;
- for 5-8 days: every 4 hours.
If necessary, the course can be continued for another 5–8 days.
For prophylactic purposes in the postoperative period, Tobradex is prescribed 1 drop 4 times a day. Therapy begins on the day of surgery, the duration of the course is 24 days. The total duration of the course does not change in cases where the use of the drug is started 1 day before the operation. If necessary, during the first 2 days after surgery, a single dose can be increased to 2 drops, the frequency of application - every 2 hours.
Shake the bottle with drops before use.
To reduce the likelihood of developing systemic adverse reactions (by reducing the systemic absorption of the drug), after instillation of Tobradex, it is recommended for 1-2 minutes to lightly press with a finger at the inner corner of the eye on the projection area of the lacrimal sacs.
Eye ointment
A single dose of the ointment is a strip 1.5 cm long, the frequency of application is 3-4 times a day. As the severity of the process decreases, the frequency of application is reduced.
Combined use
Scheme of the combined use of Tobradex:
- drops: throughout the day;
- ointment: in the evening before bedtime.
The general frequency of application of the drug is 3-4 times a day.
Side effects
Possible violations (> 10% - very often;> 1% and 0.1% and 0.01% and <0.1% - rarely; <0.01% - very rarely; with an unknown frequency - in cases of impossibility to determine the frequency appearances reportedly):
- local reactions: often - a feeling of discomfort in the eyes, pain and eye irritation; rarely - increased intraocular pressure, allergic reactions and hypersensitivity, keratitis (including pinpoint), erythema of the eyelid, itching, conjunctival hyperemia, blurred vision, foreign body sensation in the eye, conjunctival / eyelid edema, dry eye syndrome, increased lacrimation; with an unknown frequency - a decrease in visual acuity, the development of cataracts and glaucoma, photophobia, mydriasis;
- systemic reactions: rarely - laryngospasm, dysgeusia, headache, rhinorrhea.
With a long course (longer than 24 days) or an increase in the frequency of instillations of Tobradex, the following side reactions can be observed: posterior subcapsular cataract, an increase in intraocular pressure with the possible subsequent occurrence of steroid glaucoma, a slowdown in the wound healing process (in diseases that cause thinning of the cornea, its perforation is possible) …
As a result of the local immunosuppressive action of glucocorticosteroids, secondary bacterial infection can develop. In most cases, fungal corneal lesions occur with prolonged use of glucocorticosteroids. Evidence of the development of a fungal infection is the appearance of non-healing ulcers on the cornea after prolonged treatment with glucocorticosteroids. In case of purulent eye diseases in the acute course, glucocorticosteroids can enhance / mask the existing infectious process.
special instructions
The eye drops contain benzalkonium chloride, which can be absorbed by contact lenses. In this regard, it is recommended to remove contact lenses before using the drug. You can install them again 20 minutes after using the drug.
If therapy is carried out for more than 14 days, monitoring of the state of the cornea is required.
When combined with systemic aminoglycoside antibacterial drugs, it is necessary to control the overall blood picture.
To avoid contamination, do not touch the tip of the dropper bottle containing the drops and the tube containing the ointment to any surface. The bottle and tube must be closed after each use.
In cases of decreased visual acuity after the use of Tobradex, you should not drive vehicles until it is fully restored.
Drug interactions
When combined therapy with other local ophthalmic drugs, the interval between their use should be at least 5 minutes.
Analogs
Analogs of Tobradex are: DexaTobropt, Tobrazon.
Terms and conditions of storage
Store at 8–27 ° C. Keep out of the reach of children. The dropper bottle containing the drops should be stored upright.
Shelf life is 2 years.
Drops after opening the package can be used for 1 month.
Terms of dispensing from pharmacies
Dispensed by prescription.
Tobradex: prices in online pharmacies
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Drug name Price Pharmacy |
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Tobradex eye drops 5 ml 1 pc. 305 RUB Buy |
Information about the drug is generalized, provided for informational purposes only and does not replace the official instructions. Self-medication is hazardous to health!
